Literature DB >> 22510881

A new tumour suppressor enters the network of intestinal progenitor cell homeostasis.

Ee Hong Tan1, Owen James Sansom.   

Abstract

In this issue of The EMBO Journal, Wilson et al (2012) elegantly discovered an important new axis for intestinal homeostasis and cancer, using an RNAi screen to enhance the RAS-induced multivulva (MUV) phenotype in Caenorhabditis elegans.

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Year:  2012        PMID： 22510881      PMCID： PMC3365419          DOI： 10.1038/emboj.2012.115

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  11 in total

1.  Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration.

Authors:  Owen J Sansom; Karen R Reed; Anthony J Hayes; Heather Ireland; Hannah Brinkmann; Ian P Newton; Eduard Batlle; Patricia Simon-Assmann; Hans Clevers; Inke S Nathke; Alan R Clarke; Douglas J Winton
Journal:  Genes Dev       Date:  2004-06-15       Impact factor: 11.361

2.  PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas.

Authors:  Hongwu Zheng; Haoqiang Ying; Ruprecht Wiedemeyer; Haiyan Yan; Steven N Quayle; Elena V Ivanova; Ji-Hye Paik; Hailei Zhang; Yonghong Xiao; Samuel R Perry; Jian Hu; Anant Vinjamoori; Boyi Gan; Ergun Sahin; Milan G Chheda; Cameron Brennan; Y Alan Wang; William C Hahn; Lynda Chin; Ronald A DePinho
Journal:  Cancer Cell       Date:  2010-05-18       Impact factor: 31.743

3.  Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues.

Authors:  Konrad Hochedlinger; Yasuhiro Yamada; Caroline Beard; Rudolf Jaenisch
Journal:  Cell       Date:  2005-05-06       Impact factor: 41.582

4.  Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB.

Authors:  Eduard Batlle; Jeffrey T Henderson; Harry Beghtel; Maaike M W van den Born; Elena Sancho; Gerwin Huls; Jan Meeldijk; Jennifer Robertson; Marc van de Wetering; Tony Pawson; Hans Clevers
Journal:  Cell       Date:  2002-10-18       Impact factor: 41.582

5.  Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity.

Authors:  Penny Hayward; Keith Brennan; Phil Sanders; Tina Balayo; Ramanuj DasGupta; Norbert Perrimon; Alfonso Martinez Arias
Journal:  Development       Date:  2005-03-16       Impact factor: 6.868

6.  Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies.

Authors:  Seth A Ettenberg; Olga Charlat; Michael P Daley; Shanming Liu; Karen J Vincent; Darrin D Stuart; Alwin G Schuller; Jing Yuan; Beatriz Ospina; John Green; Qunyan Yu; Renee Walsh; Sharon Li; Rita Schmitz; Holger Heine; Sanela Bilic; Lance Ostrom; Rebecca Mosher; K Felix Hartlepp; Zhenping Zhu; Stephen Fawell; Yung-Mae Yao; David Stover; Peter M Finan; Jeffery A Porter; William R Sellers; Ingo M Klagge; Feng Cong
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-16       Impact factor: 11.205

7.  Acute overexpression of Myc in intestinal epithelium recapitulates some but not all the changes elicited by Wnt/beta-catenin pathway activation.

Authors:  Andrew J Finch; Laura Soucek; Melissa R Junttila; Lamorna Brown Swigart; Gerard I Evan
Journal:  Mol Cell Biol       Date:  2009-07-27       Impact factor: 4.272

8.  Identification of stem cells in small intestine and colon by marker gene Lgr5.

Authors:  Nick Barker; Johan H van Es; Jeroen Kuipers; Pekka Kujala; Maaike van den Born; Miranda Cozijnsen; Andrea Haegebarth; Jeroen Korving; Harry Begthel; Peter J Peters; Hans Clevers
Journal:  Nature       Date:  2007-10-14       Impact factor: 49.962

9.  A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesis.

Authors:  Madhuri Warren; Wei Wang; Sarah Spiden; Dongrong Chen-Murchie; David Tannahill; Karen P Steel; Allan Bradley
Journal:  Genesis       Date:  2007-01       Impact factor: 2.487

10.  Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation.

Authors:  Catherine H Wilson; Catriona Crombie; Louise van der Weyden; George Poulogiannis; Alistair G Rust; Mercedes Pardo; Tannia Gracia; Lu Yu; Jyoti Choudhary; Gino B Poulin; Rebecca E McIntyre; Douglas J Winton; H Nikki March; Mark J Arends; Andrew G Fraser; David J Adams
Journal:  EMBO J       Date:  2012-04-17       Impact factor: 11.598
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  3 in total

1.  NRBP1 is downregulated in breast cancer and NRBP1 overexpression inhibits cancer cell proliferation through Wnt/β-catenin signaling pathway.

Authors:  Hong Wei; Hongbin Wang; Qiao Ji; Jiawei Sun; Lin Tao; Xianli Zhou
Journal:  Onco Targets Ther       Date:  2015-12-14       Impact factor: 4.147

2.  Nuclear receptor binding protein 1 correlates with better prognosis and induces caspase-dependent intrinsic apoptosis through the JNK signalling pathway in colorectal cancer.

Authors:  Yi Liao; Zihuan Yang; Jintuan Huang; Hao Chen; Jun Xiang; Senmao Li; Chunyu Chen; Xuan He; Feng Lin; Zuli Yang; Jianping Wang
Journal:  Cell Death Dis       Date:  2018-04-01       Impact factor: 8.469

3.  NRBP1 negatively regulates SALL4 to reduce the invasion and migration, promote apoptosis and increase the sensitivity to chemotherapy drugs of breast cancer cells.

Authors:  Chao Yang; Xiangmei Zhang; Chao Gao; Kaiye Du; Yunjiang Liu
Journal:  Oncol Lett       Date:  2022-03-02       Impact factor: 2.967
  3 in total

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