Literature DB >> 22510017

The impact of non-severe hypoglycemic events on daytime function and diabetes management among adults with type 1 and type 2 diabetes.

Meryl Brod1, Torsten Christensen, Donald M Bushnell.   

Abstract

OBJECTIVES: To describe daytime non-severe hypoglycemic events (NSHEs), assess their impact on patient functioning and diabetes self-management, and examine if these impacts differ by diabetes type or country.
METHODS: Internet survey to adults with diabetes in the US, UK, Germany, and France.
RESULTS: Of 6756 screened respondents, 2439 reported a daytime NSHE in the past month. NSHEs occurred while active (e.g., running errands) (45.1%), 29.6% while not active (e.g., watching TV), and 23.8% at work. On average, it took half a day to respond and recover from NSHE. Respondents monitored their glucose 5.7 extra times on average over the following week. On the day of event, type 1 respondents tested significantly more often than type 2 (p<0.05). Type 2 were less likely to confirm NSHE with glucose test (p<0.001). Following NSHE, 12.6% of respondents reduced total insulin by an average of 7.6 units (SD=8.3). Total units and days with reduced dosing was significantly less, whilst number of additional glucose tests and time to recover was significantly longer if NSHE occurred at work (p<0.001). Type 1 decreased insulin doses more often (p<0.001); however, type 2 decreased a greater number of units (p<0.01). Compared with other countries, US respondents were more likely to eat a light or full meal and respondents in France took significantly longer than all other countries to recognize (p<0.05), respond to (p<0.001), and recover from (p<0.001) NSHE, used significantly more monitoring tests the day of (p<0.05) and over the subsequent week (p<0.001), and decreased their normal insulin dose more (p<0.001). Limitations of the study include potential recall bias and selection bias.
CONCLUSIONS: NSHEs are associated with a significant impact on patient functioning and diabetes management.

Entities:  

Mesh:

Year:  2012        PMID: 22510017     DOI: 10.3111/13696998.2012.686465

Source DB:  PubMed          Journal:  J Med Econ        ISSN: 1369-6998            Impact factor:   2.448


  7 in total

1.  Assessing the impact of non-severe hypoglycemic events and treatment in adults: development of the Treatment-Related Impact Measure-Non-severe Hypoglycemic Events (TRIM-HYPO).

Authors:  Meryl Brod; Lise Højbjerre; Donald M Bushnell; Charlotte Thim Hansen
Journal:  Qual Life Res       Date:  2015-06-21       Impact factor: 4.147

2.  Estimating the Impact of Diabetes Mellitus on Worker Productivity Using Self-Report, Electronic Health Record and Human Resource Data.

Authors:  David C Tabano; Melissa L Anderson; Debra P Ritzwoller; Arne Beck; Nikki Carroll; Paul A Fishman; David C Grossman
Journal:  J Occup Environ Med       Date:  2018-11       Impact factor: 2.162

3.  Severity of hypoglycaemia and health-related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe.

Authors:  Manjiri Pawaskar; Edward A Witt; Samuel S Engel; Swapnil N Rajpathak; Kristy Iglay
Journal:  Endocrinol Diabetes Metab       Date:  2018-01-19

4.  Predicting Real-world Hypoglycemia Risk in American Adults With Type 1 or 2 Diabetes Mellitus Prescribed Insulin and/or Secretagogues: Protocol for a Prospective, 12-Wave Internet-Based Panel Survey With Email Support (the iNPHORM [Investigating Novel Predictions of Hypoglycemia Occurrence Using Real-world Models] Study).

Authors:  Alexandria Ratzki-Leewing; Bridget L Ryan; Guangyong Zou; Susan Webster-Bogaert; Jason E Black; Kathryn Stirling; Kristina Timcevska; Nadia Khan; John D Buchenberger; Stewart B Harris
Journal:  JMIR Res Protoc       Date:  2022-02-11

5.  The 12-Item Hypoglycemia Impact Profile (HIP12): psychometric validation of a brief measure of the impact of hypoglycemia on quality of life among adults with type 1 or type 2 diabetes.

Authors:  Melanie Broadley; Hannah Chatwin; Uffe Søholm; Stephanie A Amiel; Jill Carlton; Bastiaan E De Galan; Christel Hendrieckx; Rory J McCrimmon; Søren E Skovlund; Frans Pouwer; Jane Speight
Journal:  BMJ Open Diabetes Res Care       Date:  2022-08

6.  A nine country study of the burden of non-severe nocturnal hypoglycaemic events on diabetes management and daily function.

Authors:  M Brod; M Wolden; T Christensen; D M Bushnell
Journal:  Diabetes Obes Metab       Date:  2013-02-25       Impact factor: 6.577

Review 7.  Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report.

Authors:  David M Maahs; Bruce A Buckingham; Jessica R Castle; Ali Cinar; Edward R Damiano; Eyal Dassau; J Hans DeVries; Francis J Doyle; Steven C Griffen; Ahmad Haidar; Lutz Heinemann; Roman Hovorka; Timothy W Jones; Craig Kollman; Boris Kovatchev; Brian L Levy; Revital Nimri; David N O'Neal; Moshe Philip; Eric Renard; Steven J Russell; Stuart A Weinzimer; Howard Zisser; John W Lum
Journal:  Diabetes Care       Date:  2016-07       Impact factor: 19.112

  7 in total

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