Literature DB >> 22505781

Pegylated Phthalocyanines: Synthesis and Spectroscopic Properties.

Hairong Li1, Frank R Fronczek, M Graça H Vicente.   

Abstract

The syntheses and spectroscopic properties of a series of pegylated zinc(II)-phthalocyanines (Zn-Pcs) containing one, two or eight tri(ethylene glycol) chains are described. The single molecular structure of a phthalonitrile precursor containing one hydroxyl and one PEG group, and its unique intermolecular hydrogen bonding are presented. The pegylated Pcs are highly soluble in polar organic solvents and have fluorescence quantum yields in the range 0.08-0.28.

Entities:  

Year:  2011        PMID： 22505781      PMCID： PMC3322642          DOI： 10.1016/j.tetlet.2011.10.002

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  22 in total

1.  Synthesis and properties of cell-targeted Zn(II)-phthalocyanine-peptide conjugates.

Authors:  Martha Sibrian-Vazquez; Javier Ortiz; Irina V Nesterova; Fernando Fernandez-Lazaro; Angela Sastre-Santos; Steven A Soper; M Graça H Vicente
Journal:  Bioconjug Chem       Date:  2007-02-06       Impact factor: 4.774

2.  Solid-phase synthesis of asymmetrically substituted "AB3-type" phthalocyanines.

Authors:  S Sibel Erdem; Irina V Nesterova; Steven A Soper; Robert P Hammer
Journal:  J Org Chem       Date:  2008-05-30       Impact factor: 4.354

3.  Synthesis, photophysical and photochemical properties of poly(oxyethylene)-substituted zinc phthalocyanines.

Authors:  Devrim Atilla; Mahmut Durmuş; Ayşe Gül Gürek; Vefa Ahsen; Tebello Nyokong
Journal:  Dalton Trans       Date:  2007-02-16       Impact factor: 4.390

4.  Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium-mediated photodynamic therapy.

Authors:  Timothy C Zhu; Jarod C Finlay; Stephen M Hahn
Journal:  J Photochem Photobiol B       Date:  2004-12-02       Impact factor: 6.252

5.  Targeting of the photocytotoxic compound AlPcS4 to Hela cells by transferrin conjugated PEG-liposomes.

Authors:  Antoon Gijsens; Annelies Derycke; Ludwig Missiaen; Dirk De Vos; Jörg Huwyler; Alex Eberle; Peter de Witte
Journal:  Int J Cancer       Date:  2002-09-01       Impact factor: 7.396

6.  Synthesis and phototoxicity of polyethylene glycol (PEG) substituted metal-free and metallo-porphyrins: effect of PEG chain length, coordinated metal, and axial ligand.

Authors:  Ryan E Mewis; Huguette Savoie; Stephen J Archibald; Ross W Boyle
Journal:  Photodiagnosis Photodyn Ther       Date:  2009-10-09       Impact factor: 3.631

7.  Glycol porphyrin derivatives as potent photodynamic inducers of apoptosis in tumor cells.

Authors:  Jarmila Králová; Tomás Bríza; Irena Moserová; Bohumil Dolenský; Petr Vasek; Pavla Poucková; Zdenek Kejík; Robert Kaplánek; Pavel Martásek; Michal Dvorák; Vladimír Král
Journal:  J Med Chem       Date:  2008-09-13       Impact factor: 7.446

8.  Mixed PEG-PE/vitamin E tumor-targeted immunomicelles as carriers for poorly soluble anti-cancer drugs: improved drug solubilization and enhanced in vitro cytotoxicity.

Authors:  Rupa R Sawant; Rishikesh M Sawant; Vladimir P Torchilin
Journal:  Eur J Pharm Biopharm       Date:  2008-04-29       Impact factor: 5.571

Review 9.  Effective drug delivery by PEGylated drug conjugates.

Authors:  Richard B Greenwald; Yun H Choe; Jeffrey McGuire; Charles D Conover
Journal:  Adv Drug Deliv Rev       Date:  2003-02-10       Impact factor: 15.470

10.  Pegylation of charged polymer-photosensitiser conjugates: effects on photodynamic efficacy.

Authors:  M R Hamblin; J L Miller; I Rizvi; H G Loew; T Hasan
Journal:  Br J Cancer       Date:  2003-09-01       Impact factor: 7.640
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  4 in total

1.  Synthesis, spectroscopic, and cellular properties of α-pegylated cis-A2B2- and A3B-types ZnPcs.

Authors:  Benson G Ongarora; Zehua Zhou; Elizabeth A Okoth; Igor Kolesnichenko; Kevin M Smith; M Graça H Vicente
Journal:  J Porphyr Phthalocyanines       Date:  2014 Oct-Nov       Impact factor: 1.811

2.  Effect of tertiary amino groups in the hydrophobic segment of an amphiphilic block copolymer on zinc phthalocyanine encapsulation and photodynamic activity.

Authors:  Makoto Obata; Eika Ishihara; Shiho Hirohara
Journal:  RSC Adv       Date:  2022-06-21       Impact factor: 4.036

3.  Low-Dose Near-Infrared Light-Activated Mitochondria-Targeting Photosensitizers for PDT Cancer Therapy.

Authors:  Wenyu Wu Klingler; Nadine Giger; Lukas Schneider; Vipin Babu; Christiane König; Patrick Spielmann; Roland H Wenger; Stefano Ferrari; Bernhard Spingler
Journal:  Int J Mol Sci       Date:  2022-08-23       Impact factor: 6.208

4.  Syntheses and Photodynamic Activity of Pegylated Cationic Zn(II)-Phthalocyanines in HEp2 Cells.

Authors:  Benson G Ongarora; Xiaoke Hu; Susan D Verberne-Sutton; Jayne C Garno; M Graça H Vicente
Journal:  Theranostics       Date:  2012-09-20       Impact factor: 11.556
  4 in total

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