Literature DB >> 22504591

Emergence of fluoroquinolone resistance in Neisseria gonorrhoeae isolates from four clinics in three regions of Kenya.

Philippe R S Lagace-Wiens1, Sarah Duncan, Joshua Kimani, Alexander Thiong'o, Juma Shafi, Scott McClelland, Eduard J Sanders, George Zhanel, Nicholas Muraguri, Supriya D Mehta.   

Abstract

We have recently reported high levels of fluoroquinolone resistance in a single region of Kenya. In this article, we report high prevalence of fluoroquinolone resistance (53.2%) in Neisseria gonorrhoeae isolates from 4 clinics in 3 additional regions of Kenya. These findings highlight the need to change first-line treatment in these settings and the need to evaluate empirical management guidelines for treatment of gonococcal infection in Kenya.

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Year:  2012        PMID: 22504591      PMCID: PMC3328140          DOI: 10.1097/OLQ.0b013e318248a85f

Source DB:  PubMed          Journal:  Sex Transm Dis        ISSN: 0148-5717            Impact factor:   2.830


  17 in total

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2.  What management is there for gonorrhea in the postquinolone era?

Authors:  John W Tapsall
Journal:  Sex Transm Dis       Date:  2006-01       Impact factor: 2.830

3.  High prevalence of quinolone resistance in Neisseria gonorrhoeae in coastal Kenya.

Authors:  Sarah Duncan; Alexander N Thiong'o; Michael Macharia; Lorraine Wamuyu; Salim Mwarumba; Benedict Mvera; Adrian D Smith; Susan Morpeth; Susan M Graham; Eduard J Sanders
Journal:  Sex Transm Infect       Date:  2011-02-09       Impact factor: 3.519

4.  Azithromycin and erythromycin resistant Neisseria gonorrhoeae following treatment with azithromycin.

Authors:  H Young; A Moyes; A McMillan
Journal:  Int J STD AIDS       Date:  1997-05       Impact factor: 1.359

5.  Emergence of quinolone resistance and cephalosporin MIC creep in Neisseria gonorrhoeae isolates from a cohort of young men in Kisumu, Kenya, 2002 to 2009.

Authors:  Supriya D Mehta; Ian Maclean; Jeckoniah O Ndinya-Achola; Stephen Moses; Irene Martin; Allan Ronald; Lawrence Agunda; Ruth Murugu; Robert C Bailey; Johan Melendez; Jonathan M Zenilman
Journal:  Antimicrob Agents Chemother       Date:  2011-05-23       Impact factor: 5.191

6.  Sexually transmitted diseases treatment guidelines, 2010.

Authors:  Kimberly A Workowski; Stuart Berman
Journal:  MMWR Recomm Rep       Date:  2010-12-17

7.  Evaluation of in vitro spectra of activity of azithromycin, clarithromycin, and erythromycin tested against strains of Neisseria gonorrhoeae by reference agar dilution, disk diffusion, and Etest methods.

Authors:  P C Mehaffey; S D Putnam; M S Barrett; R N Jones
Journal:  J Clin Microbiol       Date:  1996-02       Impact factor: 5.948

8.  Escalation in the relative prevalence of ciprofloxacin-resistant gonorrhoea among men with urethral discharge in two South African cities: association with HIV seropositivity.

Authors:  D A Lewis; L Scott; M Slabbert; S Mhlongo; A van Zijl; M Sello; N du Plessis; F Radebe; E Wasserman
Journal:  Sex Transm Infect       Date:  2008-07-02       Impact factor: 3.519

9.  Two cases of failed ceftriaxone treatment in pharyngeal gonorrhoea verified by molecular microbiological methods.

Authors:  John Tapsall; Phillip Read; Christopher Carmody; Christopher Bourne; Sanghamitra Ray; Athena Limnios; Theo Sloots; David Whiley
Journal:  J Med Microbiol       Date:  2009-05       Impact factor: 2.472

10.  Ceftriaxone-resistant Neisseria gonorrhoeae, Japan.

Authors:  Makoto Ohnishi; Takeshi Saika; Shinji Hoshina; Kazuhiro Iwasaku; Shu-ichi Nakayama; Haruo Watanabe; Jo Kitawaki
Journal:  Emerg Infect Dis       Date:  2011-01       Impact factor: 6.883

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  9 in total

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Authors:  Jenell Stewart; Elizabeth Bukusi; Fredericka A Sesay; Kevin Oware; Deborah Donnell; Olusegun O Soge; Connie Celum; Josephine Odoyo; Zachary A Kwena; Caitlin W Scoville; Lauren R Violette; Susan Morrison; Jane Simoni; R Scott McClelland; Ruanne Barnabas; Monica Gandhi; Jared M Baeten
Journal:  Trials       Date:  2022-06-16       Impact factor: 2.728

2.  Molecular screening for Neisseria gonorrhoeae antimicrobial resistance markers in Nigerian men who have sex with men and transgender women.

Authors:  Justin Hardick; Trevor A Crowell; Kara Lombardi; Akindiran Akintunde; Sunday Odeyemi; Andrew Ivo; George Eluwa; Jean Njab; Stefan D Baral; Rebecca G Nowak; Thomas C Quinn; Kent Barbian; Sarah Anzick; Sylvia Adebajo; Manhattan E Charurat; Julie Ake; Charlotte A Gaydos
Journal:  Int J STD AIDS       Date:  2018-07-04       Impact factor: 1.359

3.  Epidemiology of curable sexually transmitted infections among women at increased risk for HIV in northwestern Tanzania: inadequacy of syndromic management.

Authors:  Suzanna C Francis; Trong T Ao; Fiona M Vanobberghen; Joseph Chilongani; Ramadhan Hashim; Aura Andreasen; Deborah Watson-Jones; John Changalucha; Saidi Kapiga; Richard J Hayes
Journal:  PLoS One       Date:  2014-07-15       Impact factor: 3.240

4.  Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines.

Authors:  Emilie Alirol; Teodora E Wi; Manju Bala; Maria Luiza Bazzo; Xiang-Sheng Chen; Carolyn Deal; Jo-Anne R Dillon; Ranmini Kularatne; Jutta Heim; Rob Hooft van Huijsduijnen; Edward W Hook; Monica M Lahra; David A Lewis; Francis Ndowa; William M Shafer; Liz Tayler; Kimberly Workowski; Magnus Unemo; Manica Balasegaram
Journal:  PLoS Med       Date:  2017-07-26       Impact factor: 11.069

5.  Antimicrobial resistance (AMR) and molecular characterization of Neisseria gonorrhoeae in Ghana, 2012-2015.

Authors:  Naiki Attram; Bright Agbodzi; Helena Dela; Eric Behene; Edward O Nyarko; Nicholas N A Kyei; John A Larbi; Bernard W L Lawson; Kennedy K Addo; Mercy J Newman; Christopher A Duplessis; Nehkonti Adams; Magnus Unemo; Andrew G Letizia
Journal:  PLoS One       Date:  2019-10-10       Impact factor: 3.240

6.  Neisseria gonorrhoeae infection in female sex workers in an STI clinic in Nairobi, Kenya.

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7.  A systematic review of antimicrobial resistance in Neisseria gonorrhoeae and Mycoplasma genitalium in sub-Saharan Africa.

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Journal:  J Antimicrob Chemother       Date:  2022-07-28       Impact factor: 5.758

8.  Cross-sectional survey of treatment practices for urethritis at pharmacies, private clinics and government health facilities in coastal Kenya: many missed opportunities for HIV prevention.

Authors:  Peter M Mugo; Sarah Duncan; Samuel W Mwaniki; Alexander N Thiong'o; Evanson Gichuru; Haile Selassie Okuku; Elise M van der Elst; Adrian D Smith; Susan M Graham; Eduard J Sanders
Journal:  Sex Transm Infect       Date:  2013-05-22       Impact factor: 3.519

9.  Evaluation of WHO screening algorithm for the presumptive treatment of asymptomatic rectal gonorrhoea and chlamydia infections in at-risk MSM in Kenya.

Authors:  Eduard J Sanders; Elizabeth Wahome; Haile Selassie Okuku; Alexander N Thiong'o; Adrian D Smith; Sarah Duncan; John Mwambi; Juma Shafi; R Scott McClelland; Susan M Graham
Journal:  Sex Transm Infect       Date:  2013-12-10       Impact factor: 3.519

  9 in total

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