Literature DB >> 2250290

Vaccination of mice with lipopolysaccharide (LPS) and LPS-derived immuno-conjugates from Leptospira interrogans.

A Midwinter1, S Faine, B Adler.   

Abstract

Mice were vaccinated with lipopolysaccharide (LPS) from Leptospira interrogans serovar pomona or hardjo, or with the polysaccharide (PS) fraction of the LPS, or with an immunoconjugate of PS and diphtheria toxoid (DT). Maximum agglutinin titres were found 6-10 weeks after vaccination with LPS or PS-DT conjugate; the latter elicited antibody titres at least 10 times higher than those produced in response to LPS. Animals failed to react significantly to PS. Titres elicited by antigens of serovar pomona were higher than those elicited by serovar hardjo.

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Year:  1990        PMID： 2250290     DOI： 10.1099/00222615-33-3-199

Source DB:  PubMed          Journal:  J Med Microbiol        ISSN： 0022-2615            Impact factor:   2.472


  13 in total

1.  Characterization of an antigenic oligosaccharide from Leptospira interrogans serovar pomona and its role in immunity.

Authors:  A Midwinter; T Vinh; S Faine; B Adler
Journal:  Infect Immun       Date:  1994-12       Impact factor: 3.441

2.  Leptospiral outer membrane proteins OmpL1 and LipL41 exhibit synergistic immunoprotection.

Authors:  D A Haake; M K Mazel; A M McCoy; F Milward; G Chao; J Matsunaga; E A Wagar
Journal:  Infect Immun       Date:  1999-12       Impact factor: 3.441

3.  Global analysis of outer membrane proteins from Leptospira interrogans serovar Lai.

Authors:  Paul A Cullen; Stuart J Cordwell; Dieter M Bulach; David A Haake; Ben Adler
Journal:  Infect Immun       Date:  2002-05       Impact factor: 3.441

4.  Identification and characterization of the dTDP-rhamnose biosynthesis and transfer genes of the lipopolysaccharide-related rfb locus in Leptospira interrogans serovar Copenhageni.

Authors:  M Mitchison; D M Bulach; T Vinh; K Rajakumar; S Faine; B Adler
Journal:  J Bacteriol       Date:  1997-02       Impact factor: 3.490

Review 5.  Outer membrane proteins of pathogenic spirochetes.

Authors:  Paul A Cullen; David A Haake; Ben Adler
Journal:  FEMS Microbiol Rev       Date:  2004-06       Impact factor: 16.408

6.  The terminal portion of leptospiral immunoglobulin-like protein LigA confers protective immunity against lethal infection in the hamster model of leptospirosis.

Authors:  Everton F Silva; Marco A Medeiros; Alan J A McBride; Jim Matsunaga; Gabriela S Esteves; João G R Ramos; Cleiton S Santos; Júlio Croda; Akira Homma; Odir A Dellagostin; David A Haake; Mitermayer G Reis; Albert I Ko
Journal:  Vaccine       Date:  2007-06-14       Impact factor: 3.641

7.  Leptospirosis vaccines.

Authors:  Zhijun Wang; Li Jin; Alicja Wegrzyn
Journal:  Microb Cell Fact       Date:  2007-12-11       Impact factor: 5.328

8.  Immunogenicity comparison of conjugate vaccines composed of alginate and lipopolysaccharide of Pseudomonas aeruginosa bound to diphtheria toxoid.

Authors:  Faezeh Najafzadeh; Ghazaleh Jaberi; Reza Shapouri; Mehdi Rahnema; Ashraf Karimi-Nik; Anvarsadat Kianmehr
Journal:  Iran J Microbiol       Date:  2014-10

9.  Pseudomonas aeruginosa PAO-1 Lipopolysaccharide-Diphtheria Toxoid Conjugate Vaccine: Preparation, Characterization and Immunogenicity.

Authors:  Faezeh Najafzadeh; Reza Shapouri; Mehdi Rahnema; Shadi Rokhsartalab Azar; Anvarsadat Kianmehr
Journal:  Jundishapur J Microbiol       Date:  2015-06-27       Impact factor: 0.747

10.  Synthesis, characterization and immunological properties of Escherichia coli 0157:H7 lipopolysaccharide- diphtheria toxoid conjugate vaccine.

Authors:  Shadi Rokhsartalab-Azar; Reza Shapouri; Mehdi Rahnema; Faezeh Najafzadeh; Anvarsadat Kianmehr
Journal:  Iran J Microbiol       Date:  2015-06
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