Literature DB >> 22500837

The 1-1-1 fallacy.

Shane Crotty1.   

Abstract

T-cell help to B cells is a fundamental aspect of adaptive immunity and the generation of B-cell memory (memory B cells and plasma cells). Follicular helper CD4(+) T (Tfh) cells are the specialized providers of B-cell help, and Tfh cells depend on Bcl6 for their differentiation. This review discusses Tfh cell functions, transcription factors, and induction signals, with particular focus on the richness of the underlying biology and assessing the simplicity or complexity of each of these processes.
© 2012 John Wiley & Sons A/S.

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Year:  2012        PMID： 22500837     DOI： 10.1111/j.1600-065X.2012.01117.x

Source DB:  PubMed          Journal:  Immunol Rev        ISSN： 0105-2896            Impact factor:   12.988


  27 in total

Review 1.  Distinctive features of CD4+ T cell dysfunction in chronic viral infections.

Authors:  Antigoni Morou; Brent E Palmer; Daniel E Kaufmann
Journal:  Curr Opin HIV AIDS       Date:  2014-09       Impact factor: 4.283

Review 2.  Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? Complexities of Interpretation due to the Heterogeneity of Memory CD4 T Cells, Including T Follicular Helper Cells.

Authors:  Shane Crotty
Journal:  Cold Spring Harb Perspect Biol       Date:  2018-03-01       Impact factor: 10.005

Review 3.  Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes.

Authors:  Michael Bonelli; Han-Yu Shih; Kiyoshi Hirahara; Kentner Singelton; Arian Laurence; Amanda Poholek; Tim Hand; Yohei Mikami; Golnaz Vahedi; Yuka Kanno; John J O'Shea
Journal:  Curr Top Microbiol Immunol       Date:  2014       Impact factor: 4.291

4.  In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation.

Authors:  Runqiang Chen; Simon Bélanger; Megan A Frederick; Bin Li; Robert J Johnston; Nengming Xiao; Yun-Cai Liu; Sonia Sharma; Bjoern Peters; Anjana Rao; Shane Crotty; Matthew E Pipkin
Journal:  Immunity       Date:  2014-08-21       Impact factor: 31.745

5.  Antigen-presenting cell-derived IL-6 restricts the expression of GATA3 and IL-4 by follicular helper T cells.

Authors:  Mélanie Hercor; Maelle Anciaux; Sébastien Denanglaire; Delphine Debuisson; Oberdan Leo; Fabienne Andris
Journal:  J Leukoc Biol       Date:  2016-07-29       Impact factor: 4.962

6.  A Novel Rabies Vaccine Expressing CXCL13 Enhances Humoral Immunity by Recruiting both T Follicular Helper and Germinal Center B Cells.

Authors:  Zhao Wang; Mingming Li; Ming Zhou; Yajing Zhang; Jie Yang; Yandi Cao; Kunlun Wang; Min Cui; Huanchun Chen; Zhen F Fu; Ling Zhao
Journal:  J Virol       Date:  2017-01-18       Impact factor: 5.103

Review 7.  Harnessing CD4⁺ T cell responses in HIV vaccine development.

Authors:  Hendrik Streeck; M Patricia D'Souza; Dan R Littman; Shane Crotty
Journal:  Nat Med       Date:  2013-02-06       Impact factor: 53.440

8.  Ezrin tunes the magnitude of humoral immunity.

Authors:  Debasis Pore; Neetha Parameswaran; Ken Matsui; Matthew B Stone; Ichiko Saotome; Andrea I McClatchey; Sarah L Veatch; Neetu Gupta
Journal:  J Immunol       Date:  2013-09-16       Impact factor: 5.422

9.  Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression.

Authors:  Wei Liao; Rosanne Spolski; Peng Li; Ning Du; Erin E West; Min Ren; Suman Mitra; Warren J Leonard
Journal:  Proc Natl Acad Sci U S A       Date:  2014-02-18       Impact factor: 11.205

10.  Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation.

Authors:  Youn Soo Choi; Danelle Eto; Jessica A Yang; Christopher Lao; Shane Crotty
Journal:  J Immunol       Date:  2013-02-27       Impact factor: 5.422
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