BACKGROUND: The COPD Assessment Test (CAT) is a recently introduced instrument to assess health-related quality of life in COPD. We aimed to evaluate the longitudinal change in CAT following Pulmonary Rehabilitation (PR), and test the relationship between CAT and CRQ-Self Report (SR) over time. We hypothesised that the CAT would show similar responsiveness to PR as the CRQ-SR both in the short and medium-term. METHODS: 118 COPD patients completed an eight-week outpatient multidisciplinary PR programme. CAT, CRQ-SR and the incremental shuttle walk (ISW) were measured prior to starting PR (T1), completion of PR (T2) and 6 months after completion of PR (T3). RESULTS: There was a significant improvement in CAT, CRQ-SR and ISW immediately following PR (p < 0.001). Although there was decline between T2 and T3, CAT, CRQ-SR and ISW remained significantly better at T3 compared with T1 (ANOVA p < 0.001). Both between T1-T2 and between T2-T3, change in CAT correlated significantly with change in CRQ (both r = -0.44 and p < 0.001). The slope of the relationship between CAT change and CRQ-SR change at T1-T2 and T2-T3 was not significantly different (ANCOVA: intercept p = 0.79, interaction effect p = 0.95). CONCLUSIONS: In COPD, the CAT score is immediately responsive to PR and remains improved at 6 months. There is no significant difference in the short and medium term changes in the CAT and CRQ-SR following PR. We propose that for most clinical indications for assessing health-related quality of life in COPD, the CAT is a robust and practical alternative to longer-established instruments such as the CRQ-SR.
BACKGROUND: The COPD Assessment Test (CAT) is a recently introduced instrument to assess health-related quality of life in COPD. We aimed to evaluate the longitudinal change in CAT following Pulmonary Rehabilitation (PR), and test the relationship between CAT and CRQ-Self Report (SR) over time. We hypothesised that the CAT would show similar responsiveness to PR as the CRQ-SR both in the short and medium-term. METHODS: 118 COPD patients completed an eight-week outpatient multidisciplinary PR programme. CAT, CRQ-SR and the incremental shuttle walk (ISW) were measured prior to starting PR (T1), completion of PR (T2) and 6 months after completion of PR (T3). RESULTS: There was a significant improvement in CAT, CRQ-SR and ISW immediately following PR (p < 0.001). Although there was decline between T2 and T3, CAT, CRQ-SR and ISW remained significantly better at T3 compared with T1 (ANOVA p < 0.001). Both between T1-T2 and between T2-T3, change in CAT correlated significantly with change in CRQ (both r = -0.44 and p < 0.001). The slope of the relationship between CAT change and CRQ-SR change at T1-T2 and T2-T3 was not significantly different (ANCOVA: intercept p = 0.79, interaction effect p = 0.95). CONCLUSIONS: In COPD, the CAT score is immediately responsive to PR and remains improved at 6 months. There is no significant difference in the short and medium term changes in the CAT and CRQ-SR following PR. We propose that for most clinical indications for assessing health-related quality of life in COPD, the CAT is a robust and practical alternative to longer-established instruments such as the CRQ-SR.
Authors: Guilherme F da Silva; Maria Tereza A Morano; Maria Penha U Sales; Natalia B Olegário; Antonio George M Cavalcante; Eanes D B Pereira Journal: Qual Life Res Date: 2013-11-01 Impact factor: 4.147
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Authors: MeiLan K Han; Hana Muellerova; Douglas Curran-Everett; Mark T Dransfield; George R Washko; Elizabeth A Regan; Russell P Bowler; Terri H Beaty; John E Hokanson; David A Lynch; Paul W Jones; Antonio Anzueto; Fernando J Martinez; James D Crapo; Edwin K Silverman; Barry J Make Journal: Lancet Respir Med Date: 2012-09-03 Impact factor: 30.700
Authors: Jose Luis Lopez-Campos; Alberto Fernandez-Villar; Carmen Calero-Acuña; Cristina Represas-Represas; Cecilia Lopez-Ramírez; Virginia Leiro Fernández; Juan Jose Soler-Cataluña; Ricard Casamor Journal: Int J Chron Obstruct Pulmon Dis Date: 2015-05-27
Authors: Afroditi K Boutou; Rebecca J Tanner; Victoria M Lord; Lauren Hogg; Jane Nolan; Helen Jefford; Evelyn J Corner; Christine Falzon; Cassandra Lee; Rachel Garrod; Michael I Polkey; Nicholas S Hopkinson Journal: BMJ Open Respir Res Date: 2014-11-03