Literature DB >> 224970

Electron spin resonance (esr) investigations on blood of patients with leukemia.

W Lohmann, J Schreiber, H Gerhardt, H Breithaupt, H Löffler, H Pralle.   

Abstract

ESR investigations of lyophilized blood of patients with acute lymphatic leukemia exhibit an increase in spin concentration and an additional peak not present in control samples. This peak disappears almost completely concomittantly with a reduction in spin concentration after treating the patients with prednisolone, vincristine, and doxorubicin or after addition of 5mM of CuCl2 to blood samples. The results show that the ESR spectra of lyophilized blood samples can be utilized to follow the effect of therapy. Moreover, they suggest that the leukemic blood possesses a high concentration of antioxidants.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 224970     DOI： 10.1007/bf01008090

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  7 in total

1.  CARCINOGENIC AZO DYES, DYE-BINDING AND LIVER GLUTATHIONE.

Authors:  W J NEISH; H M DAVIES; P M REEVE
Journal:  Biochem Pharmacol       Date:  1964-09       Impact factor: 5.858

2.  AZO DYES AND RAT LIVER GLUTATHIONE.

Authors:  W J NEISH; A RYLETT
Journal:  Biochem Pharmacol       Date:  1963-08       Impact factor: 5.858

3.  Effects of oxidized fatty acids on ascites tumor metabolism.

Authors:  C W SHUSTER
Journal:  Proc Soc Exp Biol Med       Date:  1955-11

4.  Possible implications of reducing substances on the development of leukemia.

Authors:  W Lohmann; H Löffler
Journal:  Blut       Date:  1977-05

5.  A unifying biochemical theory of cancer, senescence and maximal life span.

Authors:  J Duchesne
Journal:  J Theor Biol       Date:  1977-05-07       Impact factor: 2.691

Review 6.  The sulfhydryl group and carcinogenesis.

Authors:  J S Harington
Journal:  Adv Cancer Res       Date:  1967       Impact factor: 6.242

7.  Copper as a hypoxic cell sensitizer of mammalian cells.

Authors:  I P Hesslewood; W A Cramp; D C McBrien; P Williamson; A K Lott
Journal:  Br J Cancer Suppl       Date:  1978-06
  7 in total
  3 in total

1.  On the possible involvement of ascorbic acid and copper proteins in leukemia: I. Electron spin resonance (ESR) investigations on native blood, erythrocytes, and leukocytes.

Authors:  W Lohmann; J Schreiber; W Strobelt; C Müller-Eckhardt
Journal:  Blut       Date:  1979-11

2.  On the possible involvement of ascorbic acid and copper proteins in leukemia: II. Electron spin resonance (ESR) and atomic absorption investigations on erythrocyte ghosts and plasma.

Authors:  W Lohmann; W Greulich; G Döll
Journal:  Blut       Date:  1979-11

3.  The nature of the ESR signal in lyophilized tissue and its relevance to malignancy.

Authors:  N J Dodd; H M Swartz
Journal:  Br J Cancer       Date:  1984-01       Impact factor: 7.640
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.