Literature DB >> 224947

Inhibition of the degradation of receptor-bound human choriogonadotropin by leupeptin.

M Ascoli.   

Abstract

The ability of leupeptin to block the degradation of receptor-bound human choriogonadotropin has been studied. It was found that this compound inhibited hormone degradation and intracellular cathepsin B activity in a parallel fasion, without affecting hormone-stimulated steroidogenesis.

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Year:  1979        PMID： 224947     DOI： 10.1016/0304-4165(79)90051-5

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  2 in total

1.  Lysosomal accumulation of the hormone-receptor complex during receptor-mediated endocytosis of human choriogonadotropin.

Authors:  M Ascoli
Journal:  J Cell Biol       Date:  1984-10       Impact factor: 10.539

2.  Intracellular degradation of unassembled asialoglycoprotein receptor subunits: a pre-Golgi, nonlysosomal endoproteolytic cleavage.

Authors:  J F Amara; G Lederkremer; H F Lodish
Journal:  J Cell Biol       Date:  1989-12       Impact factor: 10.539
  2 in total

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