Literature DB >> 22493634

The efficacy of arm node preserving surgery using axillary reverse mapping for preventing lymphedema in patients with breast cancer.

Jung Woo Han1, Yu Jeong Seo, Jung Eun Choi, Su Hwan Kang, Young Kyung Bae, Soo Jung Lee.   

Abstract

PURPOSE: The axillary reverse mapping (ARM) technique to identify and preserve arm nodes during sentinel lymph node biopsy (SLNB) or axillary lymph node dissection (ALND) was developed to prevent lymphedema. The purpose of this study was to investigate the location and metastatic rate of the arm node, and to evaluate the short term incidence of lymphedema after arm node preserving surgery.
METHODS: From January 2009 to October 2010, 97 breast cancer patients who underwent ARM were included. Blue-dye (2.5 mL) was injected into the ipsilateral upper-inner arm. At least 20 minutes after injection, SLNB or ALND was performed and blue-stained arm nodes and/or lymphatics were identified. Patients were divided into two groups, an arm node preserved group (70 patients had ALND, 10 patients had SLNB) and an unpreserved group (13 patients had ALND, 4 patients had SLNB). The difference in arm circumference between preoperative and postoperative time points was checked in both groups.
RESULTS: The mean number of identified blue stained arm nodes was 1.4±0.6. In the majority of patients (92%), arm nodes were located between the lower level of the axillary vein and just below the second intercostobrachial nerve. In the arm node unpreserved group, 2 patients had metastasis in their arm node. Among ALND patients, in the arm node preserved group, the difference in arm circumference between preoperative and postoperative time points in ipsilateral and contralateral arms was 0.27 cm and 0.07 cm, respectively, whereas it was 0.47 cm and -0.03 cm in the unpreserved group; one case of lymphedema was found after 6 months. No difference was found between arm node preserved and unpreserved group among SLNB patients.
CONCLUSION: Arm node preserving was possible in all breast cancer patients with identifiable arm nodes, during ALND or SLNB, except for those with high surgical N stage, and lymphedema did not develop in patients with arm node preserving surgery.

Entities:  

Keywords:  Arm; Breast neoplasms; Lymphedema; Sentinel lymph node biopsy

Year:  2012        PMID: 22493634      PMCID: PMC3318181          DOI: 10.4048/jbc.2012.15.1.91

Source DB:  PubMed          Journal:  J Breast Cancer        ISSN: 1738-6756            Impact factor:   3.588


  25 in total

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Authors:  C Peter; D Hongwan; A Küpfer; B H Lauterburg
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2.  Bioelectrical impedance analysis: proven utility in lymphedema risk assessment and therapeutic monitoring.

Authors:  Leigh C Ward
Journal:  Lymphat Res Biol       Date:  2006       Impact factor: 2.589

3.  Scientific Impact Award: Axillary reverse mapping (ARM) to identify and protect lymphatics draining the arm during axillary lymphadenectomy.

Authors:  Cristiano Boneti; Soheila Korourian; Zuleika Diaz; Carlos Santiago; Sheila Mumford; Laura Adkins; V Suzanne Klimberg
Journal:  Am J Surg       Date:  2009-10       Impact factor: 2.565

4.  Self-reported arm-lymphedema and functional impairment after breast cancer treatment--a nationwide study of prevalence and associated factors.

Authors:  Rune Gärtner; Maj-Britt Jensen; Lise Kronborg; Marianne Ewertz; Henrik Kehlet; Niels Kroman
Journal:  Breast       Date:  2010-06-18       Impact factor: 4.380

5.  Lymphedema complicated by pain and psychological distress: a case with complex treatment needs.

Authors:  M L Newman; M Brennan; S Passik
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6.  Axillary reverse mapping (ARM): a new concept to identify and enhance lymphatic preservation.

Authors:  Margaret Thompson; Soheila Korourian; Ronda Henry-Tillman; Laura Adkins; Sheilah Mumford; Kent C Westbrook; V Suzanne Klimberg
Journal:  Ann Surg Oncol       Date:  2007-05-04       Impact factor: 5.344

7.  Axillary reverse mapping: mapping and preserving arm lymphatics may be important in preventing lymphedema during sentinel lymph node biopsy.

Authors:  Cristiano Boneti; Soheila Korourian; Keiva Bland; Kristin Cox; Laura L Adkins; Ronda S Henry-Tillman; V Suzanne Klimberg
Journal:  J Am Coll Surg       Date:  2008-03-03       Impact factor: 6.113

8.  Surgical complications associated with sentinel lymph node biopsy: results from a prospective international cooperative group trial.

Authors:  Lee Gravatt Wilke; Linda M McCall; Katherine E Posther; Pat W Whitworth; Douglas S Reintgen; A Marilyn Leitch; Sheryl G A Gabram; Anthony Lucci; Charles E Cox; Kelly K Hunt; James E Herndon; Armando E Giuliano
Journal:  Ann Surg Oncol       Date:  2006-03-02       Impact factor: 5.344

9.  Prevalence of lymphedema in women with breast cancer 5 years after sentinel lymph node biopsy or axillary dissection: objective measurements.

Authors:  Sarah A McLaughlin; Mary J Wright; Katherine T Morris; Gladys L Giron; Michelle R Sampson; Julia P Brockway; Karen E Hurley; Elyn R Riedel; Kimberly J Van Zee
Journal:  J Clin Oncol       Date:  2008-10-06       Impact factor: 44.544

10.  Feasibility of axillary reverse mapping during sentinel lymph node biopsy in breast cancer patients.

Authors:  Federico Casabona; Stefano Bogliolo; Mario Valenzano Menada; Paolo Sala; Giuseppe Villa; Simone Ferrero
Journal:  Ann Surg Oncol       Date:  2009-06-09       Impact factor: 5.344

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  14 in total

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Authors:  Funda Meric-Bernstam; John C Rasmussen; Savitri Krishnamurthy; I-Chih Tan; Banghe Zhu; Jamie L Wagner; Gildy V Babiera; Elizabeth A Mittendorf; Eva M Sevick-Muraca
Journal:  Biomed Opt Express       Date:  2013-12-13       Impact factor: 3.732

Review 2.  Breast cancer-related lymphedema: risk factors, precautionary measures, and treatments.

Authors:  Tessa C Gillespie; Hoda E Sayegh; Cheryl L Brunelle; Kayla M Daniell; Alphonse G Taghian
Journal:  Gland Surg       Date:  2018-08

3.  The effectiveness of axillary reverse mapping in preventing breast cancer-related lymphedema: a meta-analysis based on randomized controlled trials.

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4.  Partial axillary lymph node dissection inferior to the intercostobrachial nerves complements sentinel node biopsy in patients with clinically node-negative breast cancer.

Authors:  Jianyi Li; Shi Jia; Wenhai Zhang; Fang Qiu; Yang Zhang; Xi Gu; Jinqi Xue
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Review 5.  The Feasibility and Oncological Safety of Axillary Reverse Mapping in Patients with Breast Cancer: A Systematic Review and Meta-Analysis of Prospective Studies.

Authors:  Chao Han; Ben Yang; Wen-Shu Zuo; Gang Zheng; Li Yang; Mei-Zhu Zheng
Journal:  PLoS One       Date:  2016-02-26       Impact factor: 3.240

6.  Lymphoscintigraphy detecting alterations of upper limb lymphatic flow following early sentinel lymph node biopsy in breast cancer.

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Journal:  Breast Cancer (Dove Med Press)       Date:  2017-04-19

7.  Prevention of lymphedema via axillary reverse mapping for arm lymph-node preservation following breast cancer surgery: a randomized controlled trial.

Authors:  Mohammed Faisal; Mohamed Gamal Sayed; Kerolos Antonious; Ahmmed Abo Bakr; Sherif Hussein Farag
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8.  Evaluation of the metastatic status of lymph nodes identified using axillary reverse mapping in breast cancer patients.

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9.  Prospective study evaluating oncological safety of axillary reverse mapping.

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Journal:  Ann Surg Oncol       Date:  2014-03-06       Impact factor: 5.344

10.  Relationship between Upper Extremity Lymphatic Drainage and Sentinel Lymph Nodes in Patients with Breast Cancer.

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Journal:  J Oncol       Date:  2019-04-01       Impact factor: 4.375

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