Literature DB >> 22482594

Real-time scintillation array dosimetry for radiotherapy: the advantages of photomultiplier detectors.

Paul Z Y Liu1, Natalka Suchowerska, Peter Abolfathi, David R McKenzie.   

Abstract

PURPOSE: In this paper, a photomultiplier tube (PMT) array dosimetry system has been developed and tested for the real-time readout of multiple scintillation signals from fiber optic dosimeters. It provides array dosimetry with the advantages in sensitivity provided by a PMT, but without the need for a separate PMT for each detector element.
METHODS: The PMT array system consisted of a multianode PMT, a multichannel data acquisition system, housing and optic fiber connections suitable for clinical use. The reproducibility, channel uniformity, channel crosstalk, acquisition speed, and sensitivity of the PMT array were quantified using a constant light source. Its performance was compared to other readout systems used in scintillation dosimetry. An in vivo HDR brachytherapy treatment was used as an example of a clinical application of the dosimetry system to the measurement of dose at multiple sites in the rectum. The PMT array system was also tested in the pulsed beam of a linear accelerator to test its response speed and its application with two separate methods of Cerenkov background removal.
RESULTS: The PMT array dosimetry system was highly reproducible with a measurement uncertainty of 0.13% for a 10 s acquisition period. Optical crosstalk between neighboring channels was accounted for by omitting every second channel. A mathematical procedure was used to account for the crosstalk in next-neighbor channels. The speed and sensitivity of the PMT array system were found be superior to CCD cameras, allowing for measurement of more rapid changes in dose rate. This was further demonstrated by measuring the dose delivered by individual photon pulses of a linear accelerator beam.
CONCLUSIONS: The PMT array system has advantages over CCD camera-based systems for the readout of scintillation light. It provided a more sensitive, more accurate, and faster response to meet the demands of future developments in treatment delivery.

Mesh:

Year:  2012        PMID: 22482594     DOI: 10.1118/1.3690465

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  3 in total

1.  Real-time dosimetry in external beam radiation therapy.

Authors:  Ramachandran Prabhakar
Journal:  World J Radiol       Date:  2013-10-28

Review 2.  A review of recent advances in optical fibre sensors for in vivo dosimetry during radiotherapy.

Authors:  S O'Keeffe; D McCarthy; P Woulfe; M W D Grattan; A R Hounsell; D Sporea; L Mihai; I Vata; G Leen; E Lewis
Journal:  Br J Radiol       Date:  2015-03-11       Impact factor: 3.039

3.  Small field detector correction factors: effects of the flattening filter for Elekta and Varian linear accelerators.

Authors:  Madelaine K Tyler; Paul Z Y Liu; Christopher Lee; David R McKenzie; Natalka Suchowerska
Journal:  J Appl Clin Med Phys       Date:  2016-05-08       Impact factor: 2.102

  3 in total

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