Literature DB >> 22476015

High beam current operation of a PETtrace™ cyclotron for 18F- production.

S Eberl1, T Eriksson, O Svedberg, J Norling, D Henderson, P Lam, M Fulham.   

Abstract

Upgrades and optimisation achieved 160 μA total target current operation of a GE PETtrace cyclotron in dual target mode for the routine production of [(18)F]FDG for >2 years. Approximately 900 GBq of (18)F(-) and >500 GBq of [(18)F]FDG can be produced routinely in a single production run, meeting the routine [(18)F]FDG requirements with our customer base and achieving economies of scale. Production of >1 TBq of (18)F(-) in a single run was achieved. Reliability, saturation and synthesis yields were not adversely affected. Crown
Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 22476015     DOI: 10.1016/j.apradiso.2012.03.007

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  5 in total

1.  Synthesis and 18F-radiolabeling of thymidine AMBF3 conjugates.

Authors:  Antonio A W L Wong; Jerome Lozada; Mathieu L Lepage; Chengcheng Zhang; Helen Merkens; Jutta Zeisler; Kuo-Shyan Lin; François Bénard; David M Perrin
Journal:  RSC Med Chem       Date:  2020-04-23

2.  Synthesis of [18F]PS13 and Evaluation as a PET Radioligand for Cyclooxygenase-1 in Monkey.

Authors:  Carlotta Taddei; Cheryl L Morse; Min-Jeong Kim; Jeih-San Liow; Jose Montero Santamaria; Andrea Zhang; Lester S Manly; Paolo Zanotti-Fregonara; Robert L Gladding; Sami S Zoghbi; Robert B Innis; Victor W Pike
Journal:  ACS Chem Neurosci       Date:  2021-01-25       Impact factor: 5.780

3.  One-Step 18F-Labeling and Preclinical Evaluation of Prostate-Specific Membrane Antigen Trifluoroborate Probes for Cancer Imaging.

Authors:  Hsiou-Ting Kuo; Mathieu L Lepage; Kuo-Shyan Lin; Jinhe Pan; Zhengxing Zhang; Zhibo Liu; Alla Pryyma; Chengcheng Zhang; Helen Merkens; Aron Roxin; David M Perrin; François Bénard
Journal:  J Nucl Med       Date:  2019-02-08       Impact factor: 10.057

4.  Imaging biomarkers or biomarker imaging?

Authors:  Markus Mitterhauser; Wolfgang Wadsak
Journal:  Pharmaceuticals (Basel)       Date:  2014-06-25

Review 5.  Nucleophilic Synthesis of 6-l-[18F]FDOPA. Is Copper-Mediated Radiofluorination the Answer?

Authors:  Raisa N Krasikova
Journal:  Molecules       Date:  2020-09-23       Impact factor: 4.411

  5 in total

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