Literature DB >> 22475440

Unique presentation of a giant mediastinal tumor as kyphosis: a case report.

Eleftherios D Spartalis1, Theodore Karatzas, Petros Konofaos, Grigorios Karagkiouzis, Gregory Kouraklis, Periklis Tomos.   

Abstract

INTRODUCTION: Although posture distortion is a common problem in elderly patients, spinal deformity caused by a thymoma has not been previously reported. Thymomas are slowly growing tumors that predominantly cause respiratory symptoms. CASE
PRESENTATION: We report the case of an 83-year-old woman who was admitted with a giant mediastinal mass that had caused progressive spinal distortion and weight loss to our department. The clinical and laboratory investigations that followed revealed one of the largest thymomas ever reported in the medical literature, presenting as a mass lesion placed at the left hemithorax. She underwent complete surgical excision of the tumor via a median sternotomy. Two years after the operation, she showed significant improvement in her posture, no pulmonary discomfort, and a gain of 20 kg; she remains disease free based on radiographic investigations.
CONCLUSIONS: In this case, a chronic asymmetric load on the spine resulted in an abnormal vertebral curvature deformity that presented as kyphosis.

Entities:  

Year:  2012        PMID: 22475440      PMCID: PMC3348087          DOI: 10.1186/1752-1947-6-99

Source DB:  PubMed          Journal:  J Med Case Rep        ISSN: 1752-1947


  16 in total

1.  The effect of load carriage on normal standing in man.

Authors:  D P THOMAS
Journal:  J Anat       Date:  1959-01       Impact factor: 2.610

Review 2.  The adult scoliosis.

Authors:  Max Aebi
Journal:  Eur Spine J       Date:  2005-11-18       Impact factor: 3.134

3.  MYASTHENIA GRAVIS AND TUMORS OF THE THYMIC REGION: REPORT OF A CASE IN WHICH THE TUMOR WAS REMOVED.

Authors:  A Blalock; M F Mason; H J Morgan; S S Riven
Journal:  Ann Surg       Date:  1939-10       Impact factor: 12.969

4.  [Radical surgery of a giant mediastinal thymoma].

Authors:  Paula Moreno; Antonio Alvarez; Dionisio Espinosa; Carlos Baamonde; Angel Salvatierra
Journal:  Cir Esp       Date:  2009-06-13       Impact factor: 1.653

5.  Severe postoperative hemorrhage after neoadjuvant chemotherapy for invasive thymoma.

Authors:  F Venuta; E A Rendina; T De Giacomo; A M Ciccone; G F Coloni
Journal:  Ann Thorac Surg       Date:  1998-09       Impact factor: 4.330

6.  Ectopic pleural thymoma presenting as a giant mass in the thoracic cavity.

Authors:  Koji Yamazaki; Ichiro Yoshino; Taro Oba; Tomofumi Yohena; Toshifumi Kameyama; Tetsuzo Tagawa; Daigo Kawano; Hidenori Koso; Yoshihiko Maehara
Journal:  Ann Thorac Surg       Date:  2007-01       Impact factor: 4.330

Review 7.  Thymoma: a focus on current therapeutic management.

Authors:  Nicolas Girard; Françoise Mornex; Paul Van Houtte; Jean-François Cordier; Paul van Schil
Journal:  J Thorac Oncol       Date:  2009-01       Impact factor: 15.609

8.  Giant thymoma in the anterior-inferior mediastinum.

Authors:  Stefan Limmer; Hartmut Merz; Peter Kujath
Journal:  Interact Cardiovasc Thorac Surg       Date:  2009-12-29

9.  Ectopic thymoma: a case for median sternotomy for complete thymectomy.

Authors:  E K Sim; C N Lee; C A Mestres; O A Adebo
Journal:  Singapore Med J       Date:  1992-08       Impact factor: 1.858

Review 10.  The management of thymoma: a systematic review and practice guideline.

Authors:  Conrad B Falkson; Andrea Bezjak; Gail Darling; Richard Gregg; Richard Malthaner; Donna E Maziak; Edward Yu; Christopher A Smith; Sheila McNair; Yee C Ung; William K Evans
Journal:  J Thorac Oncol       Date:  2009-07       Impact factor: 15.609

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  5 in total

Review 1.  Surgical management of spinal metastases of thymic carcinoma: A case report and literature review.

Authors:  Shuzhong Liu; Xi Zhou; An Song; Zhen Huo; William A Li; Radhika Rastogi; Yipeng Wang; Yong Liu
Journal:  Medicine (Baltimore)       Date:  2019-01       Impact factor: 1.817

2.  Surgical treatment of giant mediastinal tumors.

Authors:  Yu Fang; Zhiming Qin
Journal:  Turk Gogus Kalp Damar Cerrahisi Derg       Date:  2021-01-13       Impact factor: 0.332

3.  Giant thymoma presenting as a large bilateral intrathoracic mass: A case report and a comparison between median sternotomy and hemiclamshell approach.

Authors:  Daoud Daoud; Bassam Darwish; Sarmad Zahra; Monir Qaddoura
Journal:  Ann Med Surg (Lond)       Date:  2021-09-13

4.  Giant thymoma successfully resected via anterolateral thoracotomy: a case report.

Authors:  Takahiro Saito; Takashi Makino; Yoshinobu Hata; Satoshi Koezuka; Hajime Otsuka; Kazutoshi Isobe; Naobumi Tochigi; Kazutoshi Shibuya; Sakae Homma; Akira Iyoda
Journal:  J Cardiothorac Surg       Date:  2015-09-01       Impact factor: 1.637

5.  Giant thymoma successfully resected via median sternotomy and anterolateral thoracotomy: a case report.

Authors:  Yoko Azuma; Hajime Otsuka; Takashi Makino; Satoshi Koezuka; Yoichi Anami; Sota Sadamoto; Megumi Wakayama; Naobumi Tochigi; Kazutoshi Shibuya; Akira Iyoda
Journal:  J Cardiothorac Surg       Date:  2018-04-10       Impact factor: 1.637

  5 in total

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