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Literature DB >> 22473061

FUNCTIONAL NANOPARTICLES FOR MOLECULAR IMAGING GUIDED GENE DELIVERY.

Gang Liu¹, Magdalena Swierczewska, Seulki Lee, Xiaoyuan Chen.

Abstract

Gene therapy has great potential to bring tremendous changes in treatment of various diseases and disorders. However, one of the impediments to successful gene therapy is the inefficient delivery of genes to target tissues and the inability to monitor delivery of genes and therapeutic responses at the targeted site. The emergence of molecular imaging strategies has been pivotal in optimizing gene therapy; since it can allow us to evaluate the effectiveness of gene delivery noninvasively and spatiotemporally. Due to the unique physiochemical properties of nanomaterials, numerous functional nanoparticles show promise in accomplishing gene delivery with the necessary feature of visualizing the delivery. In this review, recent developments of nanoparticles for molecular imaging guided gene delivery are summarized.

Entities: CellLine Chemical Disease Gene Species

Year: 2010 PMID： 22473061 PMCID： PMC3004232 DOI： 10.1016/j.nantod.2010.10.005

Source DB: PubMed Journal: Nano Today ISSN： 1748-0132 Impact factor: 20.722

131 in total

1. Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking.

Authors: Maxime Dahan; Sabine Lévi; Camilla Luccardini; Philippe Rostaing; Béatrice Riveau; Antoine Triller
Journal: Science Date: 2003-10-17 Impact factor: 47.728

2. Recent advances in magnetofection and its potential to deliver siRNAs in vitro.

Authors: Olga Mykhaylyk; Olivier Zelphati; Edelburga Hammerschmid; Martina Anton; Joseph Rosenecker; Christian Plank
Journal: Methods Mol Biol Date: 2009

3. Intrinsically fluorescent carbon nanospheres as a nuclear targeting vector: delivery of membrane-impermeable molecule to modulate gene expression in vivo.

Authors: B Ruthrotha Selvi; Dinesh Jagadeesan; B S Suma; G Nagashankar; M Arif; K Balasubramanyam; M Eswaramoorthy; Tapas K Kundu
Journal: Nano Lett Date: 2008-09-19 Impact factor: 11.189

4. Assembly of polyethylenimine-based magnetic iron oxide vectors: insights into gene delivery.

Authors: Maria Arsianti; May Lim; Christopher P Marquis; Rose Amal
Journal: Langmuir Date: 2010-05-18 Impact factor: 3.882

Review 5. Nanoparticle-based theranostic agents.

Authors: Jin Xie; Seulki Lee; Xiaoyuan Chen
Journal: Adv Drug Deliv Rev Date: 2010-08-04 Impact factor: 15.470

6. Quantum-dot based nanoparticles for targeted silencing of HER2/neu gene via RNA interference.

Authors: Wee Beng Tan; Shan Jiang; Yong Zhang
Journal: Biomaterials Date: 2006-12-11 Impact factor: 12.479

Review 7. Neuronal nicotinic receptors: from structure to pathology.

Authors: C Gotti; F Clementi
Journal: Prog Neurobiol Date: 2004-12 Impact factor: 11.685

8. Artificial nanopores that mimic the transport selectivity of the nuclear pore complex.

Authors: Tijana Jovanovic-Talisman; Jaclyn Tetenbaum-Novatt; Anna Sophia McKenney; Anton Zilman; Reiner Peters; Michael P Rout; Brian T Chait
Journal: Nature Date: 2008-12-21 Impact factor: 49.962

9. Paramagnetic lipid-coated silica nanoparticles with a fluorescent quantum dot core: a new contrast agent platform for multimodality imaging.

Authors: Rolf Koole; Matti M van Schooneveld; Jan Hilhorst; Karolien Castermans; David P Cormode; Gustav J Strijkers; Celso de Mello Donegá; Daniel Vanmaekelbergh; Arjan W Griffioen; Klaas Nicolay; Zahi A Fayad; Andries Meijerink; Willem J M Mulder
Journal: Bioconjug Chem Date: 2008-12 Impact factor: 4.774

Review 10. Nanobioimaging and sensing of infectious diseases.

Authors: Padmavathy Tallury; Astha Malhotra; Logan M Byrne; Swadeshmukul Santra
Journal: Adv Drug Deliv Rev Date: 2009-11-25 Impact factor: 15.470

36 in total

Review 1. Theranostic nanoplatforms for simultaneous cancer imaging and therapy: current approaches and future perspectives.

Authors: Ki Young Choi; Gang Liu; Seulki Lee; Xiaoyuan Chen
Journal: Nanoscale Date: 2011-12-01 Impact factor: 7.790

Review 2. Functional magnetic nanoparticles for non-viral gene delivery and MR imaging.

Authors: Ruijun Xing; Gang Liu; Jinghan Zhu; Yanglong Hou; Xiaoyuan Chen
Journal: Pharm Res Date: 2013-09-25 Impact factor: 4.200

Review 3. Combinatorial approaches in post-polymerization modification for rational development of therapeutic delivery systems.

Authors: Yuanbo Zhong; Brian J Zeberl; Xu Wang; Juntao Luo
Journal: Acta Biomater Date: 2018-04-12 Impact factor: 8.947

FUNCTIONAL NANOPARTICLES FOR MOLECULAR IMAGING GUIDED GENE DELIVERY.

1. Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking.

2. Recent advances in magnetofection and its potential to deliver siRNAs in vitro.

3. Intrinsically fluorescent carbon nanospheres as a nuclear targeting vector: delivery of membrane-impermeable molecule to modulate gene expression in vivo.

4. Assembly of polyethylenimine-based magnetic iron oxide vectors: insights into gene delivery.

Review 5. Nanoparticle-based theranostic agents.

6. Quantum-dot based nanoparticles for targeted silencing of HER2/neu gene via RNA interference.

Review 7. Neuronal nicotinic receptors: from structure to pathology.

8. Artificial nanopores that mimic the transport selectivity of the nuclear pore complex.

9. Paramagnetic lipid-coated silica nanoparticles with a fluorescent quantum dot core: a new contrast agent platform for multimodality imaging.

Review 10. Nanobioimaging and sensing of infectious diseases.

Review 1. Theranostic nanoplatforms for simultaneous cancer imaging and therapy: current approaches and future perspectives.

Review 2. Functional magnetic nanoparticles for non-viral gene delivery and MR imaging.

Review 3. Combinatorial approaches in post-polymerization modification for rational development of therapeutic delivery systems.

Review 4. Prospects of nano-material in breast cancer management.

5. Inorganic nanovectors for nucleic acid delivery.

6. PEGylation of therapeutic oligonucletides: From linear to highly branched PEG architectures.

Review 7. Functional probes for cardiovascular molecular imaging.

8. Biomimetic RNA-silencing nanocomplexes: overcoming multidrug resistance in cancer cells.

9. Co-delivery of siRNA and therapeutic agents using nanocarriers to overcome cancer resistance.

10. DNA micelle flares for intracellular mRNA imaging and gene therapy.