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Literature DB >> 22469827

A numbers game underpins cytoplasmic mRNA transport.

Abstract

Microtubule-based mRNA transport participates in the establishment of cell asymmetries. An in vitro reconstitution assay demonstrates that localization signals present in an mRNA influence motor copy number on single RNA molecule cargoes, ultimately leading to highly polarized distributions of transcripts.

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Year: 2012 PMID： 22469827 DOI： 10.1038/ncb2475

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

16 in total

1. Processive bidirectional motion of dynein-dynactin complexes in vitro.

Authors: Jennifer L Ross; Karen Wallace; Henry Shuman; Yale E Goldman; Erika L F Holzbaur
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2. Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles.

Authors: Marina Chekulaeva; Matthias W Hentze; Anne Ephrussi
Journal: Cell Date: 2006-02-10 Impact factor: 41.582

3. The role of fs(1)K10 in the localization of the mRNA of the TGF alpha homolog gurken within the Drosophila oocyte.

Authors: T L Serano; M Karlin-McGinness; R S Cohen
Journal: Mech Dev Date: 1995-06 Impact factor: 1.882

4. Organelle, bead, and microtubule translocations promoted by soluble factors from the squid giant axon.

Authors: R D Vale; B J Schnapp; T S Reese; M P Sheetz
Journal: Cell Date: 1985-03 Impact factor: 41.582

Review 5. mRNA localization: gene expression in the spatial dimension.

Authors: Kelsey C Martin; Anne Ephrussi
Journal: Cell Date: 2009-02-20 Impact factor: 41.582

6. Multiple Myo4 motors enhance ASH1 mRNA transport in Saccharomyces cerevisiae.

Authors: Sunglan Chung; Peter A Takizawa
Journal: J Cell Biol Date: 2010-05-10 Impact factor: 10.539

7. Guidance of bidirectional motor complexes by mRNA cargoes through control of dynein number and activity.

Authors: Simon L Bullock; Alastair Nicol; Steven P Gross; Daniel Zicha
Journal: Curr Biol Date: 2006-07-25 Impact factor: 10.834

8. Independent localization of MAP2, CaMKIIα and β-actin RNAs in low copy numbers.

Authors: Martin Mikl; Georgia Vendra; Michael A Kiebler
Journal: EMBO Rep Date: 2011-09-30 Impact factor: 8.807

9. Single-molecule assays reveal that RNA localization signals regulate dynein-dynactin copy number on individual transcript cargoes.

Authors: Mamta Amrute-Nayak; Simon L Bullock
Journal: Nat Cell Biol Date: 2012-02-26 Impact factor: 28.824

10. Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for an active role of microtubules in cytoplasmic transport.

Authors: R D Allen; D G Weiss; J H Hayden; D T Brown; H Fujiwake; M Simpson
Journal: J Cell Biol Date: 1985-05 Impact factor: 10.539

2 in total

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Authors: Esperanza Fernández; Nicholas Rajan; Claudia Bagni
Journal: Front Neurosci Date: 2013-10-24 Impact factor: 4.677

Review 2. Learning and behavioral deficits associated with the absence of the fragile X mental retardation protein: what a fly and mouse model can teach us.

Authors: Ana Rita Santos; Alexandros K Kanellopoulos; Claudia Bagni
Journal: Learn Mem Date: 2014-09-16 Impact factor: 2.460

2 in total