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Literature DB >> 19239891

mRNA localization: gene expression in the spatial dimension.

Abstract

The localization of mRNAs to subcellular compartments provides a mechanism for regulating gene expression with exquisite temporal and spatial control. Recent studies suggest that a large fraction of mRNAs localize to distinct cytoplasmic domains. In this Review, we focus on cis-acting RNA localization elements, RNA-binding proteins, and the assembly of mRNAs into granules that are transported by molecular motors along cytoskeletal elements to their final destination in the cell.

Entities: Chemical Disease Gene Species

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Year: 2009 PMID： 19239891 PMCID： PMC2819924 DOI： 10.1016/j.cell.2009.01.044

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

92 in total

1. RNA-RNA interaction is required for the formation of specific bicoid mRNA 3' UTR-STAUFEN ribonucleoprotein particles.

Authors: D Ferrandon; I Koch; E Westhof; C Nüsslein-Volhard
Journal: EMBO J Date: 1997-04-01 Impact factor: 11.598

2. Redundant RNA recognition events in bicoid mRNA localization.

Authors: P M Macdonald; K Kerr
Journal: RNA Date: 1997-12 Impact factor: 4.942

3. Characterization of a beta-actin mRNA zipcode-binding protein.

Authors: A F Ross; Y Oleynikov; E H Kislauskis; K L Taneja; R H Singer
Journal: Mol Cell Biol Date: 1997-04 Impact factor: 4.272

4. Localization of Xenopus Vg1 mRNA by Vera protein and the endoplasmic reticulum.

Authors: J O Deshler; M I Highett; B J Schnapp
Journal: Science Date: 1997-05-16 Impact factor: 47.728

5. hnRNP A2 selectively binds the cytoplasmic transport sequence of myelin basic protein mRNA.

Authors: K S Hoek; G J Kidd; J H Carson; R Smith
Journal: Biochemistry Date: 1998-05-12 Impact factor: 3.162

6. Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA.

Authors: R M Long; R H Singer; X Meng; I Gonzalez; K Nasmyth; R P Jansen
Journal: Science Date: 1997-07-18 Impact factor: 47.728

7. Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast.

Authors: P A Takizawa; A Sil; J R Swedlow; I Herskowitz; R D Vale
Journal: Nature Date: 1997-09-04 Impact factor: 49.962

8. The mammalian staufen protein localizes to the somatodendritic domain of cultured hippocampal neurons: implications for its involvement in mRNA transport.

Authors: M A Kiebler; I Hemraj; P Verkade; M Köhrmann; P Fortes; R M Marión; J Ortín; C G Dotti
Journal: J Neurosci Date: 1999-01-01 Impact factor: 6.167

9. Role for mRNA localization in translational activation but not spatial restriction of nanos RNA.

Authors: S E Bergsten; E R Gavis
Journal: Development Date: 1999-02 Impact factor: 6.868

10. Transport and localization elements in myelin basic protein mRNA.

Authors: K Ainger; D Avossa; A S Diana; C Barry; E Barbarese; J H Carson
Journal: J Cell Biol Date: 1997-09-08 Impact factor: 10.539

446 in total

1. Three-dimensional tracking of single mRNA particles in Saccharomyces cerevisiae using a double-helix point spread function.

Authors: Michael A Thompson; Jason M Casolari; Majid Badieirostami; Patrick O Brown; W E Moerner
Journal: Proc Natl Acad Sci U S A Date: 2010-10-04 Impact factor: 11.205

mRNA localization: gene expression in the spatial dimension.

1. RNA-RNA interaction is required for the formation of specific bicoid mRNA 3' UTR-STAUFEN ribonucleoprotein particles.

2. Redundant RNA recognition events in bicoid mRNA localization.

3. Characterization of a beta-actin mRNA zipcode-binding protein.

4. Localization of Xenopus Vg1 mRNA by Vera protein and the endoplasmic reticulum.

5. hnRNP A2 selectively binds the cytoplasmic transport sequence of myelin basic protein mRNA.

6. Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA.

7. Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast.

8. The mammalian staufen protein localizes to the somatodendritic domain of cultured hippocampal neurons: implications for its involvement in mRNA transport.

9. Role for mRNA localization in translational activation but not spatial restriction of nanos RNA.

10. Transport and localization elements in myelin basic protein mRNA.

1. Three-dimensional tracking of single mRNA particles in Saccharomyces cerevisiae using a double-helix point spread function.

2. Organizing the oocyte: RNA localization meets phase separation.

Review 3. Local RNA translation at the synapse and in disease.

4. Dynamics of native β-actin mRNA transport in the cytoplasm.

Review 5. LKB1 signaling in advancing cell differentiation.

6. Primary role for endoplasmic reticulum-bound ribosomes in cellular translation identified by ribosome profiling.

7. Dimerization of oskar 3' UTRs promotes hitchhiking for RNA localization in the Drosophila oocyte.

8. Neuronal mRNAs travel singly into dendrites.

9. Identification of a cis-acting element that localizes mRNA to synapses.

10. Understanding the photophysics of the spinach-DFHBI RNA aptamer-fluorogen complex to improve live-cell RNA imaging.