BACKGROUND: The phosphaturic mesenchymal tumor of the craniofacial sinuses (mixed connective tissue variant) is an extremely rare, distinctive paraneoplastic syndrome that is frequently associated with oncogenic osteomalacia. METHODS: In this report is presented a case of 22 years old man indicated four years of progressive generalized pain and weakness, eventually becoming wheel-chair bound. His current presentation was for chest pain resulting from atraumatic rib fractures. RESULTS: Imaging showed osteoporosis and multiple insufficiency fractures. CT and MRI showed an ethmoid mass. He had no symptoms referable to his nose or sinuses. CONCLUSIONS: The ethmoid lesion was completely excised, the patient's laboratory parameters returned to normal levels and the patient's symptoms disappeared.
BACKGROUND: The phosphaturic mesenchymal tumor of the craniofacial sinuses (mixed connective tissue variant) is an extremely rare, distinctive paraneoplastic syndrome that is frequently associated with oncogenic osteomalacia. METHODS: In this report is presented a case of 22 years old man indicated four years of progressive generalized pain and weakness, eventually becoming wheel-chair bound. His current presentation was for chest pain resulting from atraumatic rib fractures. RESULTS: Imaging showed osteoporosis and multiple insufficiency fractures. CT and MRI showed an ethmoid mass. He had no symptoms referable to his nose or sinuses. CONCLUSIONS: The ethmoid lesion was completely excised, the patient's laboratory parameters returned to normal levels and the patient's symptoms disappeared.
Authors: X Gonzalez-Compta; M Mañós-Pujol; M Foglia-Fernandez; E Peral; E Condom; T Claveguera; M Dicenta-Sousa Journal: J Laryngol Otol Date: 1998-04 Impact factor: 1.469