Literature DB >> 22461285

Mechanism of action of strontium ranelate: what are the facts?

João Eurico Fonseca1, Maria Luisa Brandi.   

Abstract

Year:  2010        PMID: 22461285      PMCID: PMC2898000     

Source DB:  PubMed          Journal:  Clin Cases Miner Bone Metab        ISSN: 1724-8914


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  17 in total

1.  Osteoblasts play key roles in the mechanisms of action of strontium ranelate.

Authors:  T C Brennan; M S Rybchyn; W Green; S Atwa; A D Conigrave; R S Mason
Journal:  Br J Pharmacol       Date:  2009-06-25       Impact factor: 8.739

2.  Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study.

Authors:  J Y Reginster; E Seeman; M C De Vernejoul; S Adami; J Compston; C Phenekos; J P Devogelaer; M Diaz Curiel; A Sawicki; S Goemaere; O H Sorensen; D Felsenberg; P J Meunier
Journal:  J Clin Endocrinol Metab       Date:  2005-02-22       Impact factor: 5.958

3.  Theoretical model for the interpretation of BMD scans in patients stopping strontium ranelate treatment.

Authors:  Glen M Blake; Ignac Fogelman
Journal:  J Bone Miner Res       Date:  2006-09       Impact factor: 6.741

4.  Strontium ranelate inhibits bone resorption while maintaining bone formation in alveolar bone in monkeys (Macaca fascicularis).

Authors:  J Buehler; P Chappuis; J L Saffar; Y Tsouderos; A Vignery
Journal:  Bone       Date:  2001-08       Impact factor: 4.398

5.  Induction of a program gene expression during osteoblast differentiation with strontium ranelate.

Authors:  Ling-Ling Zhu; Samir Zaidi; Yuanzhen Peng; Hang Zhou; Baljit S Moonga; Alexia Blesius; Isabelle Dupin-Roger; Mone Zaidi; Li Sun
Journal:  Biochem Biophys Res Commun       Date:  2007-01-30       Impact factor: 3.575

6.  S12911-2 reduces bone loss induced by short-term immobilization in rats.

Authors:  M Hott; P Deloffre; Y Tsouderos; P J Marie
Journal:  Bone       Date:  2003-07       Impact factor: 4.398

7.  Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants.

Authors:  S D Bain; C Jerome; V Shen; I Dupin-Roger; P Ammann
Journal:  Osteoporos Int       Date:  2008-12-19       Impact factor: 4.507

8.  Histomorphometric and microCT analysis of bone biopsies from postmenopausal osteoporotic women treated with strontium ranelate.

Authors:  Monique E Arlot; Yebin Jiang; Harry K Genant; Jenny Zhao; Brigitte Burt-Pichat; Jean-Paul Roux; Pierre D Delmas; Pierre J Meunier
Journal:  J Bone Miner Res       Date:  2008-02       Impact factor: 6.741

9.  An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats.

Authors:  P J Marie; M Hott; D Modrowski; C De Pollak; J Guillemain; P Deloffre; Y Tsouderos
Journal:  J Bone Miner Res       Date:  1993-05       Impact factor: 6.741

10.  Strontium ranelate treatment improves trabecular and cortical intrinsic bone tissue quality, a determinant of bone strength.

Authors:  Patrick Ammann; Isabelle Badoud; Sébastien Barraud; Romain Dayer; René Rizzoli
Journal:  J Bone Miner Res       Date:  2007-09       Impact factor: 6.741

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  8 in total

Review 1.  Bone-seeking agents for the treatment of bone disorders.

Authors:  Jacqueline Cawthray; Ellen Wasan; Kishor Wasan
Journal:  Drug Deliv Transl Res       Date:  2017-08       Impact factor: 4.617

2.  The effect of strontium ranelate on the healing of a fractured ulna with bone gap in rabbit.

Authors:  Mohd Rafiq Mohd Ibrahim; Simmrat Singh; Azhar Mahmood Merican; Hanumantha Rao Balaji Raghavendran; Malliga Raman Murali; Sangeetha Vasudevaraj Naveen; Tunku Kamarul
Journal:  BMC Vet Res       Date:  2016-06-16       Impact factor: 2.741

3.  The Effect of Strontium Ranelate Gel on Bone Formation in Calvarial Critical Size Defects.

Authors:  Hani El Nahass; Nada Nour El Din; Sherine Adel Nasry
Journal:  Open Access Maced J Med Sci       Date:  2017-12-12

4.  Effect of strontium ranelate on pain behavior in an experimental model of osteoarthritis.

Authors:  T A Rodrigues; A J B Sampaio; I D P Nunes; M S S Cartágenes; J B S Garcia
Journal:  Braz J Med Biol Res       Date:  2017-08-07       Impact factor: 2.590

Review 5.  Strontium ranelate as a possible disease-modifying osteoarthritis drug: a systematic review.

Authors:  T A Rodrigues; A O Freire; B F Bonfim; M S S Cartágenes; J B S Garcia
Journal:  Braz J Med Biol Res       Date:  2018-06-18       Impact factor: 2.590

6.  The Effect of Strontium Ranelate on Fracture Healing: An Animal Study.

Authors:  Ourania I Koukou; Lampros D Pappas; Pelagia Chloropoulou; Maria A Kouroupi; Konstantinos I Koukos; Georgia Karpathiou; Antonios A Galanos; Georgios I Drosos; Evaggelos Magnisalis; Alexandra N Giatromanolaki; Dionysios Alexandros Verettas
Journal:  Biomed Res Int       Date:  2020-11-24       Impact factor: 3.411

7.  Prophylactic and Therapeutic Use of Strontium Ranelate Reduces the Progression of Experimental Osteoarthritis.

Authors:  Thiago A Rodrigues; Abner de Oliveira Freire; Heetor C O Carvalho; Gyl E B Silva; José W Vasconcelos; Rosane N M Guerra; Maria do Socorro de Sousa Cartágenes; João B S Garcia
Journal:  Front Pharmacol       Date:  2018-09-19       Impact factor: 5.810

8.  In vitro cellular testing of strontium/calcium substituted phosphate glass discs and microspheres shows potential for bone regeneration.

Authors:  Uresha Patel; Laura Macri-Pellizzeri; Kazi M Zakir Hossain; Brigitte E Scammell; David M Grant; Colin A Scotchford; Alex C Hannon; Andrew R Kennedy; Emma R Barney; Ifty Ahmed; Virginie Sottile
Journal:  J Tissue Eng Regen Med       Date:  2019-02-17       Impact factor: 3.963

  8 in total

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