Literature DB >> 22460929

Genetics and psychiatry: a proposal for the application of the precautionary principle.

Corinna Porteri1.   

Abstract

The paper suggests an application of the precautionary principle to the use of genetics in psychiatry focusing on scientific uncertainty. Different levels of uncertainty are taken into consideration--from the acknowledgement that the genetic paradigm is only one of the possible ways to explain psychiatric disorders, via the difficulties related to the diagnostic path and genetic methods, to the value of the results of studies carried out in this field. Considering those uncertainties, some measures for the use of genetics in psychiatry are suggested. Some of those measures are related to the conceptual limits of the genetic paradigm; others are related to present knowledge and should be re-evaluated.

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Year:  2013        PMID： 22460929     DOI： 10.1007/s11019-012-9408-6

Source DB:  PubMed          Journal:  Med Health Care Philos        ISSN： 1386-7423


  16 in total

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Review 2.  Testing hypotheses on specific environmental causal effects on behavior.

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3.  Mental disorders and genetics: the ethical context: conclusions and recommendations.

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Review 4.  Complexity and accountability: the witches' brew of psychiatric genetics.

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Review 6.  Opportunities for psychiatry from genetic findings.

Authors:  M Rutter; R Plomin
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Review 8.  New findings in the genetics of major psychoses.

Authors:  Markus M Nöthen; Vanessa Nieratschker; Sven Cichon; Marcella Rietschel
Journal:  Dialogues Clin Neurosci       Date:  2010       Impact factor: 5.986

9.  Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.

Authors:  S I Shyn; J Shi; J B Kraft; J B Potash; J A Knowles; M M Weissman; H A Garriock; J S Yokoyama; P J McGrath; E J Peters; W A Scheftner; W Coryell; W B Lawson; D Jancic; P V Gejman; A R Sanders; P Holmans; S L Slager; D F Levinson; S P Hamilton
Journal:  Mol Psychiatry       Date:  2009-12-29       Impact factor: 15.992

10.  Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.

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  2 in total

1.  Possible association between suicide committed under influence of ethanol and a variant in the AUTS2 gene.

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2.  Predictive Psychiatric Genetic Testing in Minors: An Exploration of the Non-Medical Benefits.

Authors:  Arianna Manzini; Danya F Vears
Journal:  J Bioeth Inq       Date:  2017-12-11       Impact factor: 1.352
  2 in total

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