Literature DB >> 2246074

Anti-inflammatory effects of onions: inhibition of chemotaxis of human polymorphonuclear leukocytes by thiosulfinates and cepaenes.

W Dorsch1, E Schneider, T Bayer, W Breu, H Wagner.   

Abstract

Seven different synthetic thiosulfinates, and cepaene- and/or thiosulfinate-rich onion extracts were found to inhibit in vitro the chemotaxis of human granulocytes induced by formyl-methionine-leucine-phenylalanine in a dose-dependent manner and at a concentration range of 0.1-100 microM. Diphenylthiosulfinate showed the highest activity and was found to be more active than prednisolone. The anti-inflammatory properties of onion extracts are related, at least in part, to the inhibition of inflammatory cell influx by thiosulfinates and cepaenes.

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Year:  1990        PMID： 2246074     DOI： 10.1159/000235221

Source DB:  PubMed          Journal:  Int Arch Allergy Appl Immunol        ISSN： 0020-5915


  5 in total

1.  A new proprietary onion extract gel improves the appearance of new scars: a randomized, controlled, blinded-investigator study.

Authors:  Zoe D Draelos; Leslie Baumann; Alan B Fleischer; Stefan Plaum; Edward V Avakian; Bhushan Hardas
Journal:  J Clin Aesthet Dermatol       Date:  2012-06

2.  Determination of anti-inflammatory activities of standardised preparations of plant- and mushroom-based foods.

Authors:  Dhanushka Gunawardena; Kirubakaran Shanmugam; Mitchell Low; Louise Bennett; Suresh Govindaraghavan; Richard Head; Lezanne Ooi; Gerald Münch
Journal:  Eur J Nutr       Date:  2013-05-08       Impact factor: 5.614

3.  A rethinking on the benefits and drawbacks of common antioxidants and a proposal to look for the antioxidants in allium products as ideal agents: a review.

Authors:  K T Augusti; Regi Jose; G R Sajitha; Paul Augustine
Journal:  Indian J Clin Biochem       Date:  2011-08-09

4.  Discovery and characterization of a novel lachrymatory factor synthase in Petiveria alliacea and its influence on alliinase-mediated formation of biologically active organosulfur compounds.

Authors:  Rabi A Musah; Quan He; Roman Kubec
Journal:  Plant Physiol       Date:  2009-08-19       Impact factor: 8.340

Review 5.  A review of anti-inflammatory, antioxidant, and immunomodulatory effects of Allium cepa and its main constituents.

Authors:  Narges Marefati; Vahideh Ghorani; Farzaneh Shakeri; Marzie Boskabady; Farzaneh Kianian; Ramin Rezaee; Mohammad Hosein Boskabady
Journal:  Pharm Biol       Date:  2021-12       Impact factor: 3.503
  5 in total

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