UNLABELLED: Modest energy restriction combined with resistance training (RT) has been shown in nonlactating women to protect bone during periods of weight loss. However, there is a paucity of research on dietary interventions and exercise in lactating women aimed at promoting bone health and weight loss. PURPOSE: This study aimed to investigate the effects of energy restriction and exercise on bone mineral density (BMD) and hormones during lactation. METHODS: At 4 wk postpartum, participants were randomized to either a 16-wk intervention (diet restricted by 500 kcal and RT 3 d·wk) group (IG = 14) or minimal care group (CG = 13). Measurements included BMD by DXA, three 24-h dietary recalls, and hormones. Repeated-measures ANOVA was used to test for group differences over time. RESULTS:Energy intake decreased more in IG (613 ± 521 kcal) than CG (171 ± 435 kcal) (P = 0.03). IG lost more weight (5.8 ± 3.5 kg vs CG = 1.6 ± 5.4 kg, P = 0.02). BMD decreased over time, P < 0.01, with no group differences in lumbar spine (IG = 3.4% ± 2.5%, CG = 3.7% ± 3.3%) or hip (IG and CG = 3.1 ± 1.8%). Prolactin and estradiol decreased over time in both groups, P < 0.01. Basal growth hormone remained stable; however, there was a significant increase in growth hormone response to exercise in IG. CONCLUSIONS: These results suggest that moderate energy restriction combined with RT promotes weight loss with no adverse effects on BMD during lactation.
RCT Entities:
UNLABELLED: Modest energy restriction combined with resistance training (RT) has been shown in nonlactating women to protect bone during periods of weight loss. However, there is a paucity of research on dietary interventions and exercise in lactating women aimed at promoting bone health and weight loss. PURPOSE: This study aimed to investigate the effects of energy restriction and exercise on bone mineral density (BMD) and hormones during lactation. METHODS: At 4 wk postpartum, participants were randomized to either a 16-wk intervention (diet restricted by 500 kcal and RT 3 d·wk) group (IG = 14) or minimal care group (CG = 13). Measurements included BMD by DXA, three 24-h dietary recalls, and hormones. Repeated-measures ANOVA was used to test for group differences over time. RESULTS: Energy intake decreased more in IG (613 ± 521 kcal) than CG (171 ± 435 kcal) (P = 0.03). IG lost more weight (5.8 ± 3.5 kg vs CG = 1.6 ± 5.4 kg, P = 0.02). BMD decreased over time, P < 0.01, with no group differences in lumbar spine (IG = 3.4% ± 2.5%, CG = 3.7% ± 3.3%) or hip (IG and CG = 3.1 ± 1.8%). Prolactin and estradiol decreased over time in both groups, P < 0.01. Basal growth hormone remained stable; however, there was a significant increase in growth hormone response to exercise in IG. CONCLUSIONS: These results suggest that moderate energy restriction combined with RT promotes weight loss with no adverse effects on BMD during lactation.
Authors: Jodie M Dodd; Andrea R Deussen; Cecelia M O'Brien; Danielle A J M Schoenaker; Amanda Poprzeczny; Adrienne Gordon; Suzanne Phelan Journal: Nutr Rev Date: 2018-08-01 Impact factor: 7.110
Authors: Sheila Bornstein; Sue A Brown; Phuong T Le; Xunde Wang; Victoria DeMambro; Mark C Horowitz; Ormond MacDougald; Roland Baron; Sutada Lotinun; Gerard Karsenty; Wei Wei; Mathieu Ferron; Christopher S Kovacs; David Clemmons; Yihong Wan; Clifford J Rosen Journal: Endocrinology Date: 2014-06-10 Impact factor: 4.736