Literature DB >> 22456988

Antithrombotic therapy in patients with acute coronary syndrome and diabetes mellitus.

S Farhan1, I Tentzeris, M K Freynhofer, B Vogel, K Huber.   

Abstract

Acute coronary syndrome (ACS) is associated with high mortality even in the acute phase as well as in the post-acute (chronic) phase. Diabetes mellitus type 2 (DM-2), on the other hand, further increases mortality after ACS. Several new antiplatelet and antithrombotic drugs available for clinical use have also been investigated in patients with DM-2, and the guidelines of the European Society of Cardiology (ESC) were recently adapted. However, in daily clinical practice choosing the most suitable regimen is a challenge in many cases. This review article aims to shed light on and simplify antiplatelet and antithrombotic therapy in ACS patients with DM-2 in order to ease the clinician's decision-making.

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Year:  2012        PMID: 22456988     DOI: 10.1007/s00059-012-3610-4

Source DB:  PubMed          Journal:  Herz        ISSN: 0340-9937            Impact factor:   1.443


  121 in total

1.  In vivo effect of insulin on intracellular calcium concentrations: relation to insulin resistance.

Authors:  S Baldi; A Natali; G Buzzigoli; A Q Galvan; A M Sironi; E Ferrannini
Journal:  Metabolism       Date:  1996-11       Impact factor: 8.694

2.  Fibrinolytic activity is highly influenced by long-term glycemic control in Type 1 diabetic patients.

Authors:  I Seljeflot; J R Larsen; K Dahl-Jørgensen; K F Hanssen; H Arnesen
Journal:  J Thromb Haemost       Date:  2006-03       Impact factor: 5.824

3.  High-risk patients with acute coronary syndromes treated with low-molecular-weight or unfractionated heparin: outcomes at 6 months and 1 year in the SYNERGY trial.

Authors:  Kenneth W Mahaffey; Marc Cohen; Jyotsna Garg; Elliott Antman; Neal S Kleiman; Shaun G Goodman; Lisa G Berdan; Craig J Reist; Anatoly Langer; Harvey D White; Philip E Aylward; Jacques J Col; James J Ferguson; Robert M Califf
Journal:  JAMA       Date:  2005-11-23       Impact factor: 56.272

4.  Study design and rationale of a comparison of prasugrel and clopidogrel in medically managed patients with unstable angina/non-ST-segment elevation myocardial infarction: the TaRgeted platelet Inhibition to cLarify the Optimal strateGy to medicallY manage Acute Coronary Syndromes (TRILOGY ACS) trial.

Authors:  Chee Tang Chin; Matthew T Roe; Keith A A Fox; Dorairaj Prabhakaran; Debra A Marshall; Helene Petitjean; Yuliya Lokhnygina; Eileen Brown; Paul W Armstrong; Harvey D White; E Magnus Ohman
Journal:  Am Heart J       Date:  2010-07       Impact factor: 4.749

5.  Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial.

Authors:  Jonas Oldgren; Andrzej Budaj; Christopher B Granger; Yasser Khder; Juliet Roberts; Agneta Siegbahn; Jan G P Tijssen; Frans Van de Werf; Lars Wallentin
Journal:  Eur Heart J       Date:  2011-05-07       Impact factor: 29.983

6.  Blood glucose may condition factor VII levels in diabetic and normal subjects.

Authors:  A Ceriello; D Giugliano; A Quatraro; P Dello Russo; R Torella
Journal:  Diabetologia       Date:  1988-12       Impact factor: 10.122

7.  Drug-eluting stenting followed by cilostazol treatment reduces late restenosis in patients with diabetes mellitus the DECLARE-DIABETES Trial (A Randomized Comparison of Triple Antiplatelet Therapy with Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation in Diabetic Patients).

Authors:  Seung-Whan Lee; Seong-Wook Park; Young-Hak Kim; Sung-Cheol Yun; Duk-Woo Park; Cheol Whan Lee; Myeong-Ki Hong; Hyun-Sook Kim; Jae-Ki Ko; Jae-Hyeong Park; Jae-Hwan Lee; Si Wan Choi; In-Whan Seong; Yoon Haeng Cho; Nae-Hee Lee; June Hong Kim; Kook-Jin Chun; Seung-Jung Park
Journal:  J Am Coll Cardiol       Date:  2008-03-25       Impact factor: 24.094

8.  Bivalirudin in patients undergoing primary angioplasty for acute myocardial infarction (HORIZONS-AMI): 1-year results of a randomised controlled trial.

Authors:  Roxana Mehran; Alexandra J Lansky; Bernhard Witzenbichler; Giulio Guagliumi; Jan Z Peruga; Bruce R Brodie; Dariusz Dudek; Ran Kornowski; Franz Hartmann; Bernard J Gersh; Stuart J Pocock; S Chiu Wong; Eugenia Nikolsky; Louise Gambone; Lynn Vandertie; Helen Parise; George D Dangas; Gregg W Stone
Journal:  Lancet       Date:  2009-08-28       Impact factor: 79.321

Review 9.  Platelet hyperactivity in type 2 diabetes: role of antiplatelet agents.

Authors:  Arun Natarajan; Azfar G Zaman; Sally M Marshall
Journal:  Diab Vasc Dis Res       Date:  2008-06       Impact factor: 3.291

10.  Intravenous platelet blockade with cangrelor during PCI.

Authors:  Deepak L Bhatt; A Michael Lincoff; C Michael Gibson; Gregg W Stone; Steven McNulty; Gilles Montalescot; Neal S Kleiman; Shaun G Goodman; Harvey D White; Kenneth W Mahaffey; Charles V Pollack; Steven V Manoukian; Petr Widimsky; Derek P Chew; Fernando Cura; Ivan Manukov; Frantisek Tousek; M Zubair Jafar; Jaspal Arneja; Simona Skerjanec; Robert A Harrington
Journal:  N Engl J Med       Date:  2009-12-10       Impact factor: 91.245

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