| Literature DB >> 22455748 |
Yves S Y Hsieh1, Brendan L Wilkinson, Mitchell R O'Connell, Joel P Mackay, Jacqueline M Matthews, Richard J Payne.
Abstract
The synthesis of sublancin 168, a unique S-glucosylated bacteriocin antibiotic, is described. The natural product and two S-glycosylated variants were successfully prepared via native chemical ligation followed by folding. The synthetic glycopeptides were shown to possess primarily an α-helical secondary structure by CD and NMR studies.Entities:
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Year: 2012 PMID: 22455748 DOI: 10.1021/ol300557g
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005