[Studies on the antidiabetic effect of konjac glucomannan with different molecular chains on experimental diabetes mice].

The antidiabetic effect of konjac glucomannan with different molecular chains on experimental diabetes mice was studied. The result showed that KGM- I, KGM-II, KGM-III and konjac flour can lower blood sugar of alloxan-induced hyperglycemic mice. When the dose was 1.5 g/kg, the decrease rates of blood sugar was 55.37%, 80.60%, 33.44% and 40.9%, respectively. It also showed that KGM-II (Po, 0.2 g/kg. d x 7d) can significantly intensify DTH induced by DNFB and improve phagocytosing function of peritoneal macrophage (PM phi) separetely.