| Literature DB >> 22454295 |
Abstract
The enhancement of surface enhanced Raman scattering (SERS) with nanogap-rich silver nanoislands surrounding glass nanopillars at wafer level is reported. High-density hot spots are generated by increasing the number of nanogap-rich nanoislands within a detection volume. The SERS substrate shows a high enhancement factor of over 10(7) with excellent signal uniformity (∼7.8%) and it enables the label-free detection of aqueous DNA base molecules at nanomolar level.Entities:
Mesh:
Substances:
Year: 2012 PMID: 22454295 DOI: 10.1002/adma.201104696
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849