Literature DB >> 22447723

A potential role for zinc alterations in the pathogenesis of Alzheimer's disease.

Ganna Lyubartseva1, Mark A Lovell.   

Abstract

Alzheimer's disease (AD), one of the major causes of disability and mortality in Western societies, is a progressive age-related neurodegenerative disorder. Increasing evidence suggests that the etiology of AD may involve disruptions of zinc (Zn) homeostasis. This review discusses current evidence supporting a potential role of Zn and zinc transporters (ZnTs) in processing of the amyloid beta protein precursor (APP) and amyloid beta (Aβ) peptide generation and aggregation.
Copyright © 2012 International Union of Biochemistry and Molecular Biology, Inc.

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Year:  2012        PMID： 22447723      PMCID： PMC3635097          DOI： 10.1002/biof.199

Source DB:  PubMed          Journal:  Biofactors        ISSN： 0951-6433            Impact factor:   6.113


  115 in total

1.  Alterations of zinc transporter proteins ZnT-1, ZnT-4 and ZnT-6 in preclinical Alzheimer's disease brain.

Authors:  Ganna Lyubartseva; Jennifer L Smith; William R Markesbery; Mark A Lovell
Journal:  Brain Pathol       Date:  2009-04-07       Impact factor: 6.508

2.  Decline in verbal memory during preclinical Alzheimer's disease: examination of the effect of APOE genotype.

Authors:  Kelly L Lange; Mark W Bondi; David P Salmon; Douglas Galasko; Dean C Delis; Ronald G Thomas; Leon J Thal
Journal:  J Int Neuropsychol Soc       Date:  2002-11       Impact factor: 2.892

Review 3.  Alzheimer's disease and post-operative cognitive dysfunction.

Authors:  Zhongcong Xie; Rudolph E Tanzi
Journal:  Exp Gerontol       Date:  2006-03-27       Impact factor: 4.032

Review 4.  Metals and amyloid-beta in Alzheimer's disease.

Authors:  Christa J Maynard; Ashley I Bush; Colin L Masters; Roberto Cappai; Qiao-Xin Li
Journal:  Int J Exp Pathol       Date:  2005-06       Impact factor: 1.925

Review 5.  Mammalian zinc transporters.

Authors:  R J McMahon; R J Cousins
Journal:  J Nutr       Date:  1998-04       Impact factor: 4.798

6.  Serum zinc in the progression of Alzheimer's disease.

Authors:  Jiang Dong; J David Robertson; William R Markesbery; Mark A Lovell
Journal:  J Alzheimers Dis       Date:  2008-11       Impact factor: 4.472

7.  The Montgomery-Asberg Depression Rating Scale and the Cornell Scale for Depression in Dementia: a validation study with patients exhibiting early-onset dementia.

Authors:  Ruslan Leontjevas; Susan van Hooren; Ans Mulders
Journal:  Am J Geriatr Psychiatry       Date:  2009-01       Impact factor: 4.105

8.  Neuronal zinc exchange with the blood vessel wall promotes cerebral amyloid angiopathy in an animal model of Alzheimer's disease.

Authors:  Avi L Friedlich; Joo-Yong Lee; Thomas van Groen; Robert A Cherny; Irene Volitakis; Toby B Cole; Richard D Palmiter; Jae-Young Koh; Ashley I Bush
Journal:  J Neurosci       Date:  2004-03-31       Impact factor: 6.167

9.  Alzheimer disease in the US population: prevalence estimates using the 2000 census.

Authors:  Liesi E Hebert; Paul A Scherr; Julia L Bienias; David A Bennett; Denis A Evans
Journal:  Arch Neurol       Date:  2003-08

10.  Metal concentrations in plasma and cerebrospinal fluid in patients with Alzheimer's disease.

Authors:  Lars Gerhardsson; Thomas Lundh; Lennart Minthon; Elisabet Londos
Journal:  Dement Geriatr Cogn Disord       Date:  2008-05-05       Impact factor: 2.959
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  8 in total

1.  Does SCFD1 rs10139154 Polymorphism Decrease Alzheimer's Disease Risk?

Authors:  Polyxeni Stamati; Vasileios Siokas; Athina-Maria Aloizou; Emmanouil Karampinis; Stylianos Arseniou; Valerii N Rakitskii; Aristidis Tsatsakis; Demetrios A Spandidos; Illana Gozes; Panayiotis D Mitsias; Dimitrios P Bogdanos; Georgios M Hadjigeorgiou; Efthimios Dardiotis
Journal:  J Mol Neurosci       Date:  2019-07-02       Impact factor: 3.444

Review 2.  Zinc and its effects on oxidative stress in Alzheimer's disease.

Authors:  Ye Yuan; Fenglan Niu; Ya Liu; Na Lu
Journal:  Neurol Sci       Date:  2014-02-13       Impact factor: 3.307

3.  Zinc homeostasis and neurodegenerative disorders.

Authors:  Bernadeta Szewczyk
Journal:  Front Aging Neurosci       Date:  2013-07-19       Impact factor: 5.750

4.  Obesity and age-related alterations in the gene expression of zinc-transporter proteins in the human brain.

Authors:  R H Olesen; T M Hyde; J E Kleinman; K Smidt; J Rungby; A Larsen
Journal:  Transl Psychiatry       Date:  2016-06-14       Impact factor: 6.222

Review 5.  Perspectives for New and More Efficient Multifunctional Ligands for Alzheimer's Disease Therapy.

Authors:  Agnieszka Zagórska; Anna Jaromin
Journal:  Molecules       Date:  2020-07-23       Impact factor: 4.411

Review 6.  Critical Role of Zinc as Either an Antioxidant or a Prooxidant in Cellular Systems.

Authors:  Sung Ryul Lee
Journal:  Oxid Med Cell Longev       Date:  2018-03-20       Impact factor: 6.543

7.  Greater Circulating Copper Concentrations and Copper/Zinc Ratios are Associated with Lower Psychological Distress, But Not Cognitive Performance, in a Sample of Australian Older Adults.

Authors:  Michelle Mravunac; Ewa A Szymlek-Gay; Robin M Daly; Blaine R Roberts; Melissa Formica; Jenny Gianoudis; Stella L O'Connell; Caryl A Nowson; Barbara R Cardoso
Journal:  Nutrients       Date:  2019-10-17       Impact factor: 5.717

8.  Mechanism of Zn2+ and Ca2+ Binding to Human S100A1.

Authors:  Viktoriia E Baksheeva; Andrei Yu Roman; Claude Villard; François Devred; Deborah Byrne; Dahbia Yatoui; Arthur O Zalevsky; Alisa A Vologzhannikova; Andrey S Sokolov; Sergei E Permyakov; Andrey V Golovin; Gary S Shaw; Philipp O Tsvetkov; Evgeni Yu Zernii
Journal:  Biomolecules       Date:  2021-12-03
  8 in total

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