OBJECTIVE: We sought to study long-term (neuro)developmental and behavioral outcome of pregnancies complicated by intrauterine growth restriction at term in relation to induction of labor or an expectant management. STUDY DESIGN:Parents of 2-year-old children included in the Disproportionate Intrauterine Growth Intervention Trial at Term (DIGITAT) answered the Ages and Stages Questionnaire (ASQ) and Child Behavior Checklist (CBCL). RESULTS: We approached 582 (89.5%) of 650 parents. The response rate was 50%. Of these children, 27% had an abnormal score on the ASQ and 13% on the CBCL. Results of the ASQ and the CBCL for the 2 policies were comparable. Low birthweight, positive Morbidity Assessment Index score, and admission to intermediate care increased the risk of an abnormal outcome of the ASQ. This effect was not seen for the CBCL. CONCLUSION: In women with intrauterine growth restriction at term, neither a policy of induction of labor nor expectant management affect developmental and behavioral outcome when compared to expectant management.
RCT Entities:
OBJECTIVE: We sought to study long-term (neuro)developmental and behavioral outcome of pregnancies complicated by intrauterine growth restriction at term in relation to induction of labor or an expectant management. STUDY DESIGN: Parents of 2-year-old children included in the Disproportionate Intrauterine Growth Intervention Trial at Term (DIGITAT) answered the Ages and Stages Questionnaire (ASQ) and Child Behavior Checklist (CBCL). RESULTS: We approached 582 (89.5%) of 650 parents. The response rate was 50%. Of these children, 27% had an abnormal score on the ASQ and 13% on the CBCL. Results of the ASQ and the CBCL for the 2 policies were comparable. Low birthweight, positive Morbidity Assessment Index score, and admission to intermediate care increased the risk of an abnormal outcome of the ASQ. This effect was not seen for the CBCL. CONCLUSION: In women with intrauterine growth restriction at term, neither a policy of induction of labor nor expectant management affect developmental and behavioral outcome when compared to expectant management.
Authors: Nir Melamed; Ahmet Baschat; Yoav Yinon; Apostolos Athanasiadis; Federico Mecacci; Francesc Figueras; Vincenzo Berghella; Amala Nazareth; Muna Tahlak; H David McIntyre; Fabrício Da Silva Costa; Anne B Kihara; Eran Hadar; Fionnuala McAuliffe; Mark Hanson; Ronald C Ma; Rachel Gooden; Eyal Sheiner; Anil Kapur; Hema Divakar; Diogo Ayres-de-Campos; Liran Hiersch; Liona C Poon; John Kingdom; Roberto Romero; Moshe Hod Journal: Int J Gynaecol Obstet Date: 2021-03 Impact factor: 3.561
Authors: Christoph C Lees; Roberto Romero; Tamara Stampalija; Andrea Dall'Asta; Greggory A DeVore; Federico Prefumo; Tiziana Frusca; Gerard H A Visser; John C Hobbins; Ahmet A Baschat; Caterina M Bilardo; Henry L Galan; Stuart Campbell; Dev Maulik; Francesc Figueras; Wesley Lee; Julia Unterscheider; Herbert Valensise; Fabricio Da Silva Costa; Laurent J Salomon; Liona C Poon; Enrico Ferrazzi; Giancarlo Mari; Giuseppe Rizzo; John C Kingdom; Torvid Kiserud; Kurt Hecher Journal: Am J Obstet Gynecol Date: 2022-01-10 Impact factor: 10.693
Authors: Katarina Guttmannova; Karl G Hill; Jennifer A Bailey; Lacey Hartigan; Candice M Small; J David Hawkins Journal: Infant Child Dev Date: 2016-11-16
Authors: Jorien M Kerstjens; Ard Nijhuis; Christian V Hulzebos; Deirdre E van Imhoff; Aleid G van Wassenaer-Leemhuis; Ingrid C van Haastert; Enrico Lopriore; Titia Katgert; Renate M Swarte; Richard A van Lingen; Twan L Mulder; Céleste R Laarman; Katerina Steiner; Peter H Dijk Journal: PLoS One Date: 2015-07-20 Impact factor: 3.240
Authors: Francesc Figueras; Eduard Gratacos; Marta Rial; Ilan Gull; Ladislav Krofta; Marek Lubusky; Rogelio Cruz-Martinez; Mónica Cruz-Lemini; Miguel Martinez-Rodriguez; Pamela Socias; Cristina Aleuanlli; Mauro C Parra Cordero Journal: BMJ Open Date: 2017-06-15 Impact factor: 2.692
Authors: Diana M Bond; Adrienne Gordon; Jon Hyett; Bradley de Vries; Angela E Carberry; Jonathan Morris Journal: Cochrane Database Syst Rev Date: 2015-11-24