Literature DB >> 22444690

Elevated HIF-1α expression of acute myelogenous leukemia stem cells in the endosteal hypoxic zone may be a cause of minimal residual disease in bone marrow after chemotherapy.

T Matsunaga, O Imataki, E Torii, T Kameda, K Shide, H Shimoda, A Kamiunten, M Sekine, Y Taniguchi, S Yamamoto, T Hidaka, K Katayose, Y Kubuki, H Dobashi, S Bandoh, H Ohnishi, F Fukai, K Shimoda.   

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Year:  2012        PMID： 22444690     DOI： 10.1016/j.leukres.2012.02.028

Source DB:  PubMed          Journal:  Leuk Res        ISSN： 0145-2126            Impact factor:   3.156


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  18 in total

1.  AML1/ETO cooperates with HIF1α to promote leukemogenesis through DNMT3a transactivation.

Authors:  X N Gao; F Yan; J Lin; L Gao; X L Lu; S C Wei; N Shen; J X Pang; Q Y Ning; Y Komeno; A L Deng; Y H Xu; J L Shi; Y H Li; D E Zhang; C Nervi; S J Liu; L Yu
Journal:  Leukemia       Date:  2015-03-02       Impact factor: 11.528

2.  Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA.

Authors:  Itaru Kato; Yoko Nishinaka; Masahiro Nakamura; Ayse U Akarca; Akira Niwa; Hiroki Ozawa; Kenichi Yoshida; Makiko Mori; Dapeng Wang; Makiko Morita; Hiroo Ueno; Yusuke Shiozawa; Yuichi Shiraishi; Satoru Miyano; Rajeev Gupta; Katsutsugu Umeda; Kenichiro Watanabe; Katsuyoshi Koh; Souichi Adachi; Toshio Heike; Megumu K Saito; Masashi Sanada; Seishi Ogawa; Teresa Marafioti; Akira Watanabe; Tatsutoshi Nakahata; Tariq Enver
Journal:  Blood       Date:  2017-04-19       Impact factor: 22.113

3.  Phase I/II study of the hypoxia-activated prodrug PR104 in refractory/relapsed acute myeloid leukemia and acute lymphoblastic leukemia.

Authors:  Marina Konopleva; Peter F Thall; Cecilia Arana Yi; Gautam Borthakur; Andrew Coveler; Carlos Bueso-Ramos; Juliana Benito; Sergej Konoplev; Yongchuan Gu; Farhad Ravandi; Elias Jabbour; Stefan Faderl; Deborah Thomas; Jorge Cortes; Tapan Kadia; Steven Kornblau; Naval Daver; Naveen Pemmaraju; Hoang Q Nguyen; Jennie Feliu; Hongbo Lu; Caimiao Wei; William R Wilson; Teresa J Melink; John C Gutheil; Michael Andreeff; Elihu H Estey; Hagop Kantarjian
Journal:  Haematologica       Date:  2015-02-14       Impact factor: 9.941

Review 4.  Integration of hypoxic HIF-α signaling in blood cancers.

Authors:  L Schito; S Rey; M Konopleva
Journal:  Oncogene       Date:  2017-05-22       Impact factor: 9.867

5.  AKR1C3 is a biomarker of sensitivity to PR-104 in preclinical models of T-cell acute lymphoblastic leukemia.

Authors:  Donya Moradi Manesh; Jad El-Hoss; Kathryn Evans; Jennifer Richmond; Cara E Toscan; Lauryn S Bracken; Ashlee Hedrick; Rosemary Sutton; Glenn M Marshall; William R Wilson; Raushan T Kurmasheva; Catherine Billups; Peter J Houghton; Malcolm A Smith; Hernan Carol; Richard B Lock
Journal:  Blood       Date:  2015-06-26       Impact factor: 22.113

6.  Targeting hypoxia in the leukemia microenvironment.

Authors:  Juliana Benito; Zhihong Zeng; Marina Konopleva; William R Wilson
Journal:  Int J Hematol Oncol       Date:  2013-08-01

7.  Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models.

Authors:  Juliana Benito; Marc S Ramirez; Niki Zacharias Millward; Juliana Velez; Karine G Harutyunyan; Hongbo Lu; Yue-Xi Shi; Polina Matre; Rodrigo Jacamo; Helen Ma; Sergej Konoplev; Teresa McQueen; Andrei Volgin; Marina Protopopova; Hong Mu; Jaehyuk Lee; Pratip K Bhattacharya; Joseph R Marszalek; R Eric Davis; James A Bankson; Jorge E Cortes; Charles P Hart; Michael Andreeff; Marina Konopleva
Journal:  Clin Cancer Res       Date:  2015-11-24       Impact factor: 12.531

8.  Inhibiting autophagy targets human leukemic stem cells and hypoxic AML blasts by disrupting mitochondrial homeostasis.

Authors:  Kaitlyn M Dykstra; Hannah R S Fay; Ashish C Massey; Neng Yang; Matthew Johnson; Scott Portwood; Monica L Guzman; Eunice S Wang
Journal:  Blood Adv       Date:  2021-04-27

Review 9.  Driving CAR T Stem Cell Targeting in Acute Myeloid Leukemia: The Roads to Success.

Authors:  Ilaria M Michelozzi; Efstratios Kirtsios; Alice Giustacchini
Journal:  Cancers (Basel)       Date:  2021-06-05       Impact factor: 6.639

Review 10.  The Role of Hypoxic Bone Marrow Microenvironment in Acute Myeloid Leukemia and Future Therapeutic Opportunities.

Authors:  Samantha Bruno; Manuela Mancini; Sara De Santis; Cecilia Monaldi; Michele Cavo; Simona Soverini
Journal:  Int J Mol Sci       Date:  2021-06-25       Impact factor: 5.923
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