Literature DB >> 22441994

What is the prevalence of MRSA colonization in elective spine cases?

Antonia F Chen1, Srinivas Chivukula, Lloydine J Jacobs, Matthew W Tetreault, Joon Y Lee.   

Abstract

BACKGROUND: The incidence of methicillin-resistant Staphylococcus aureus (MRSA) infection is increasing. However, the prevalence of MRSA colonization among patients undergoing spine surgery is unclear. QUESTIONS/PURPOSES: We therefore (1) determined the prevalence of MRSA colonization in a population of patients scheduled for elective spine surgery; and (2) evaluated whether MRSA screening and treatment reduce the rate of early wound complications.
METHODS: We retrospectively reviewed prospectively collected data from 1002 patients undergoing elective spine surgery in 2010. There were 719 primary and 283 revision surgeries. Instrumentation was used in 72.0% cases and autologous iliac crest bone graft was taken in 65.1%. Twelve patients were lost to followup; of the remaining 990 patients, 503 were screened for MRSA and 487 were not. MRSA-colonized patients were treated with mupirocin and chlorhexidine. An early wound complication was defined as wound drainage or the presence of an abscess. Patients were followed for a minimum of 3 months (average, 7 months; range, 3-545 days).
RESULTS: Of the patients undergoing elective spine surgery and screened for MRSA, 14 of 503 (2.8%) were colonized with MRSA. The rates of early wound complications were similar for patients who were screened and pretreated for MRSA (17 of 503 [3.4%]) compared with those who were not (17 of 487 [3.5%]).
CONCLUSIONS: The colonization rate for MRSA in our elective spine surgery population was comparable to that in the arthroplasty literature. LEVEL OF EVIDENCE: Level III, retrospective comparative study. See the Guidelines for Authors for a complete description of levels of evidence.

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Year:  2012        PMID: 22441994      PMCID: PMC3442011          DOI: 10.1007/s11999-012-2316-5

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  19 in total

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4.  Surgical site infection in spinal surgery: detection and management based on serial C-reactive protein measurements.

Authors:  Byung-Uk Kang; Sang-Ho Lee; Yong Ahn; Won-Chul Choi; Young-Geun Choi
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Review 5.  Cost analysis of surgical site infections.

Authors:  Joshua A Urban
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Authors:  M A Weinstein; J P McCabe; F P Cammisa
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7.  Preoperative, intraoperative, and postoperative measures to further reduce spinal infections.

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8.  Infection after total knee arthroplasty.

Authors:  A W Blom; J Brown; A H Taylor; G Pattison; S Whitehouse; G C Bannister
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9.  A preoperative decolonization protocol for staphylococcus aureus prevents orthopaedic infections.

Authors:  Nalini Rao; Barbara Cannella; Lawrence S Crossett; A J Yates; Richard McGough
Journal:  Clin Orthop Relat Res       Date:  2008-04-11       Impact factor: 4.176

Review 10.  The significance of nasal carriage of Staphylococcus aureus and the incidence of postoperative wound infection.

Authors:  R P Wenzel; T M Perl
Journal:  J Hosp Infect       Date:  1995-09       Impact factor: 3.926

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  6 in total

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Authors:  M Daniel Wongworawat
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2.  Editor's Spotlight/Take 5: Vancomycin Prophylaxis for Total Joint Arthroplasty: Incorrectly Dosed and Has a Higher Rate of Periprosthetic Infection Than Cefazolin.

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Journal:  Clin Orthop Relat Res       Date:  2017-05-01       Impact factor: 4.176

Review 3.  Pre-operative Decolonization as a Strategy to Reduce Surgical Site Infection.

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Journal:  Curr Infect Dis Rep       Date:  2019-08-31       Impact factor: 3.725

Review 4.  Staphylococcus aureus screening and decolonization in orthopaedic surgery and reduction of surgical site infections.

Authors:  Antonia F Chen; Charles B Wessel; Nalini Rao
Journal:  Clin Orthop Relat Res       Date:  2013-03-06       Impact factor: 4.176

Review 5.  The use of surveillance and preventative measures for methicillin-resistant staphylococcus aureus infections in surgical patients.

Authors:  Kevin T Kavanagh; Lindsay E Calderon; Daniel M Saman; Said K Abusalem
Journal:  Antimicrob Resist Infect Control       Date:  2014-05-14       Impact factor: 4.887

6.  Burden of Staphylococcus aureus infections after orthopedic surgery in Germany.

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