Literature DB >> 22440162

Ocular surface changes in eyes with glaucoma filtering blebs.

Celso Ricardo Neves Mendes1, Richard Yudi Hida, Niro Kasahara.   

Abstract

PURPOSE: To analyse the ocular surface changes in eyes with functioning filtering blebs and to correlate with the size of the bleb.
MATERIALS AND METHODS: Forty eyes of 40 glaucomatous patients with functioning blebs and 40 normal control subjects underwent double vital staining for ocular surface evaluation, tear film break-up-time (BUT) and Schirmer I-test in a standardized fashion. Mann-Whitney U-test and Spearman's rank correlation were used to correlate bleb height and horizontal extent with BUT, Schirmer I-test, rose bengal and fluorescein staining scores.
RESULTS: Eyes with functioning blebs presented minimal, but significantly, higher rose bengal and fluorescein staining than controls (p < 0.000). The staining correlated poorly with the height and extent of the bleb. The Schirmer test in the study group showed greater measurements than controls, however, BUT showed shorter values in the study group as compared to controls (p < 0.05).
CONCLUSION: Filtering blebs can interfere with the ocular surface stability causing few dry eyes like signs.

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Year:  2012        PMID: 22440162     DOI: 10.3109/02713683.2011.635400

Source DB:  PubMed          Journal:  Curr Eye Res        ISSN: 0271-3683            Impact factor:   2.424


  8 in total

1.  Meibomian gland loss due to trabeculectomy.

Authors:  Hideto Sagara; Tetsuju Sekiryu; Hiroki Noji; Masashi Ogasawara; Yukinori Sugano; Hiroko Horikiri
Journal:  Jpn J Ophthalmol       Date:  2014-05-24       Impact factor: 2.447

2.  Relationship between OSDI questionnaire and ocular surface changes in glaucomatous patients.

Authors:  Adriano Guarnieri; Elena Carnero; Anne-Marie Bleau; Belén Alfonso-Bartolozzi; Javier Moreno-Montañés
Journal:  Int Ophthalmol       Date:  2019-12-07       Impact factor: 2.031

3.  Effect of chronic anti-glaucoma medications and trabeculectomy on tear osmolarity.

Authors:  S-Y Lee; T T Wong; J Chua; C Boo; Y F Soh; L Tong
Journal:  Eye (Lond)       Date:  2013-07-12       Impact factor: 3.775

4.  Ocular lubricant use in medically and surgically treated glaucoma: a retrospective longitudinal analysis.

Authors:  Jayant Venkatramani Iyer; Yang Zhao; Fiona Pin Miao Lim; Louis Tong; Tina Tzee Ling Wong
Journal:  Clin Ophthalmol       Date:  2017-06-23

Review 5.  Clinical Tear Fluid Proteomics-A Novel Tool in Glaucoma Research.

Authors:  Janika Nättinen; Ulla Aapola; Praveena Nukareddy; Hannu Uusitalo
Journal:  Int J Mol Sci       Date:  2022-07-23       Impact factor: 6.208

Review 6.  Confocal Microscopy and Anterior Segment Optical Coherence Tomography Imaging of the Ocular Surface and Bleb Morphology in Medically and Surgically Treated Glaucoma Patients: A Review.

Authors:  Carmela Carnevale; Ivano Riva; Gloria Roberti; Manuele Michelessi; Lucia Tanga; Alice C Verticchio Vercellin; Luca Agnifili; Gianluca Manni; Alon Harris; Luciano Quaranta; Francesco Oddone
Journal:  Pharmaceuticals (Basel)       Date:  2021-06-18

7.  Dry Eye Disease in Patients with Functioning Filtering Blebs after Trabeculectomy.

Authors:  Hong Ji; Yingting Zhu; Yingying Zhang; Zuohong Li; Jian Ge; Yehong Zhuo
Journal:  PLoS One       Date:  2016-03-31       Impact factor: 3.240

8.  The ocular surface after successful glaucoma filtration surgery: a clinical, in vivo confocal microscopy, and immune-cytology study.

Authors:  Luca Agnifili; Lorenza Brescia; Francesco Oddone; Matteo Sacchi; Erminia D'Ugo; Guido Di Marzio; Fabiana Perna; Ciro Costagliola; Rodolfo Mastropasqua
Journal:  Sci Rep       Date:  2019-08-05       Impact factor: 4.379

  8 in total

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