Literature DB >> 2242290

A computerised technique for the quantitative assessment of resorption cavities in trabecular bone.

N J Garrahan1, P I Croucher, J E Compston.   

Abstract

A computerised technique is described for the quantitative assessment of resorption cavities in iliac trabecular bone. Using an Ibas II image analyser, the original bone surface, eroded by bone resorbing cells, is reconstructed using a curve fitting technique that maintains a smooth continuity with the trabecular bone on either side of the cavity. Resorption depths are measured using an interactive elastic circle; all identified cavities are measured regardless of whether or not resorption is complete, and the measurements made include mean and maximum cavity depth, cavity length, area, and adjacent trabecular widths. Results in 13 normal subjects are presented. The technique is reproducible, simple to operate, relatively rapid, and can be applied to less sophisticated image analysis systems.

Mesh:

Year:  1990        PMID: 2242290     DOI: 10.1016/8756-3282(90)90076-b

Source DB:  PubMed          Journal:  Bone        ISSN: 1873-2763            Impact factor:   4.398


  10 in total

Review 1.  Mechanisms of bone loss and gain in untreated and treated osteoporosis.

Authors:  Juliet Compston
Journal:  Endocrine       Date:  2002-02       Impact factor: 3.633

2.  Bone adaptation in osteoporosis.

Authors:  Mei-Shu Shih
Journal:  Curr Osteoporos Rep       Date:  2012-09       Impact factor: 5.096

3.  Age-related changes in resorption cavity characteristics in human trabecular bone.

Authors:  P I Croucher; N J Garrahan; R W Mellish; J E Compston
Journal:  Osteoporos Int       Date:  1991-09       Impact factor: 4.507

4.  Histomorphometric interpretation of bone biopsies for the evaluation of osteoporosis treatment.

Authors:  Juliet E Compston
Journal:  Bonekey Rep       Date:  2012-04-04

5.  Three-dimensional characterization of resorption cavity size and location in human vertebral trabecular bone.

Authors:  M G Goff; C R Slyfield; S R Kummari; E V Tkachenko; S E Fischer; Y H Yi; M G Jekir; T M Keaveny; C J Hernandez
Journal:  Bone       Date:  2012-04-03       Impact factor: 4.398

Review 6.  From histology to micro-CT: Measuring and modeling resorption cavities and their relation to bone competence.

Authors:  Jef Vanderoost; G Harry van Lenthe
Journal:  World J Radiol       Date:  2014-09-28

7.  Reduced bone formation in patients with osteoporosis associated with inflammatory bowel disease.

Authors:  P I Croucher; S Vedi; R J Motley; N J Garrahan; M R Stanton; J E Compston
Journal:  Osteoporos Int       Date:  1993-09       Impact factor: 4.507

8.  Bone turnover in non-steroid treated rheumatoid arthritis.

Authors:  J E Compston; S Vedi; P I Croucher; N J Garrahan; M M O'Sullivan
Journal:  Ann Rheum Dis       Date:  1994-03       Impact factor: 19.103

9.  Voxel size and measures of individual resorption cavities in three-dimensional images of cancellous bone.

Authors:  Evgeniy V Tkachenko; Craig R Slyfield; Ryan E Tomlinson; Justin R Daggett; David L Wilson; Christopher John Hernandez
Journal:  Bone       Date:  2009-05-28       Impact factor: 4.398

Review 10.  Interest of Bone Histomorphometry in Bone Pathophysiology Investigation: Foundation, Present, and Future.

Authors:  Pascale Chavassieux; Roland Chapurlat
Journal:  Front Endocrinol (Lausanne)       Date:  2022-07-28       Impact factor: 6.055

  10 in total

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