Literature DB >> 22414944

Obesity and the brain: how convincing is the addiction model?

Hisham Ziauddeen1, I Sadaf Farooqi, Paul C Fletcher.   

Abstract

An increasingly influential perspective conceptualizes both obesity and overeating as a food addiction accompanied by corresponding brain changes. Because there are far-reaching implications for clinical practice and social policy if it becomes widely accepted, a critical evaluation of this model is important. We examine the current evidence for the link between addiction and obesity, identifying several fundamental shortcomings in the model, as well as weaknesses and inconsistencies in the empirical support for it from human neuroscientific research.

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Year:  2012        PMID: 22414944     DOI: 10.1038/nrn3212

Source DB:  PubMed          Journal:  Nat Rev Neurosci        ISSN: 1471-003X            Impact factor:   34.870


  99 in total

1.  An fMRI study of obesity, food reward, and perceived caloric density. Does a low-fat label make food less appealing?

Authors:  Janet Ng; Eric Stice; Sonja Yokum; Cara Bohon
Journal:  Appetite       Date:  2011-04-08       Impact factor: 3.868

Review 2.  Compulsive overeating as an addiction disorder. A review of theory and evidence.

Authors:  Caroline Davis; Jacqueline C Carter
Journal:  Appetite       Date:  2009-06-12       Impact factor: 3.868

3.  Altered temporal difference learning in bulimia nervosa.

Authors:  Guido K W Frank; Jeremy R Reynolds; Megan E Shott; Randall C O'Reilly
Journal:  Biol Psychiatry       Date:  2011-06-29       Impact factor: 13.382

4.  The influence of trait and induced state impulsivity on food intake in normal-weight healthy women.

Authors:  Ramona Guerrieri; Chantal Nederkoorn; Kasia Stankiewicz; Hugo Alberts; Nicole Geschwind; Carolien Martijn; Anita Jansen
Journal:  Appetite       Date:  2006-12-23       Impact factor: 3.868

5.  Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell.

Authors:  P Rada; N M Avena; B G Hoebel
Journal:  Neuroscience       Date:  2005       Impact factor: 3.590

6.  The obese brain: association of body mass index and insulin sensitivity with resting state network functional connectivity.

Authors:  Stephanie Kullmann; Martin Heni; Ralf Veit; Caroline Ketterer; Fritz Schick; Hans-Ulrich Häring; Andreas Fritsche; Hubert Preissl
Journal:  Hum Brain Mapp       Date:  2011-04-21       Impact factor: 5.038

Review 7.  Sugar and fat bingeing have notable differences in addictive-like behavior.

Authors:  Nicole M Avena; Pedro Rada; Bartley G Hoebel
Journal:  J Nutr       Date:  2009-01-28       Impact factor: 4.798

Review 8.  Impulsivity as a vulnerability marker for substance-use disorders: review of findings from high-risk research, problem gamblers and genetic association studies.

Authors:  Antonio Verdejo-García; Andrew J Lawrence; Luke Clark
Journal:  Neurosci Biobehav Rev       Date:  2008-01-17       Impact factor: 8.989

Review 9.  Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction.

Authors:  Barry J Everitt; David Belin; Daina Economidou; Yann Pelloux; Jeffrey W Dalley; Trevor W Robbins
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2008-10-12       Impact factor: 6.237

10.  Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement.

Authors:  Jeffrey W Dalley; Tim D Fryer; Laurent Brichard; Emma S J Robinson; David E H Theobald; Kristjan Lääne; Yolanda Peña; Emily R Murphy; Yasmene Shah; Katrin Probst; Irina Abakumova; Franklin I Aigbirhio; Hugh K Richards; Young Hong; Jean-Claude Baron; Barry J Everitt; Trevor W Robbins
Journal:  Science       Date:  2007-03-02       Impact factor: 47.728

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  150 in total

1.  Tossing the baby out with the bathwater after a brief rinse? The potential downside of dismissing food addiction based on limited data.

Authors:  Nicole M Avena; Ashley N Gearhardt; Mark S Gold; Gene-Jack Wang; Marc N Potenza
Journal:  Nat Rev Neurosci       Date:  2012-06-20       Impact factor: 34.870

Review 2.  Shared and unique mechanisms underlying binge eating disorder and addictive disorders.

Authors:  Erica M Schulte; Carlos M Grilo; Ashley N Gearhardt
Journal:  Clin Psychol Rev       Date:  2016-02-04

Review 3.  Changes in Reward after Gastric Bypass: the Advantages and Disadvantages.

Authors:  Samantha Scholtz; Anthony P Goldstone; Carel W le Roux
Journal:  Curr Atheroscler Rep       Date:  2015-10       Impact factor: 5.113

Review 4.  The Macronutrients, Appetite, and Energy Intake.

Authors:  Alicia L Carreiro; Jaapna Dhillon; Susannah Gordon; Kelly A Higgins; Ashley G Jacobs; Breanna M McArthur; Benjamin W Redan; Rebecca L Rivera; Leigh R Schmidt; Richard D Mattes
Journal:  Annu Rev Nutr       Date:  2016-07-17       Impact factor: 11.848

5.  Obesity, food, and addiction: emerging neuroscience and clinical and public health implications.

Authors:  Marc N Potenza
Journal:  Neuropsychopharmacology       Date:  2014-01       Impact factor: 7.853

Review 6.  Stress and eating behaviors.

Authors:  Y H C Yau; M N Potenza
Journal:  Minerva Endocrinol       Date:  2013-09       Impact factor: 2.184

7.  Neuropsychological assessment as a predictor of weight loss in obese adolescents.

Authors:  M Kulendran; I Vlaev; C Sugden; D King; H Ashrafian; P Gately; A Darzi
Journal:  Int J Obes (Lond)       Date:  2013-10-29       Impact factor: 5.095

8.  Should pathological gambling and obesity be considered addictive disorders? A factor analytic study in a nationally representative sample.

Authors:  Carlos Blanco; María García-Anaya; Melanie Wall; José Carlos Pérez de Los Cobos; Ewelina Swierad; Shuai Wang; Nancy M Petry
Journal:  Drug Alcohol Depend       Date:  2015-02-25       Impact factor: 4.492

9.  Exploration of "food addiction" in overweight and obese treatment-seeking adults.

Authors:  Dawn M Eichen; Michelle R Lent; Edie Goldbacher; Gary D Foster
Journal:  Appetite       Date:  2013-03-25       Impact factor: 3.868

Review 10.  Comparing the effects of food restriction and overeating on brain reward systems.

Authors:  Nicole M Avena; Susan Murray; Mark S Gold
Journal:  Exp Gerontol       Date:  2013-03-25       Impact factor: 4.032

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