Literature DB >> 22413127

A simple fluorometric assay for DNA exonuclease activity based on graphene oxide.

Jieon Lee1, Dal-Hee Min.   

Abstract

A new assay platform for DNA exonuclease activity is developed based on the preferential binding of single-stranded DNA (ssDNA) over double-stranded DNA (dsDNA) to graphene oxide. This approach allows a simple and quantitative activity measurement in a short time at low cost.

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Year:  2012        PMID： 22413127     DOI： 10.1039/c2an16214h

Source DB:  PubMed          Journal:  Analyst        ISSN： 0003-2654            Impact factor:   4.616


  6 in total

1.  Quantitative Microplate Assay for Real-Time Nuclease Kinetics.

Authors:  Jonas Eriksson; Ülo Langel
Journal:  PLoS One       Date:  2016-04-21       Impact factor: 3.240

Review 2.  Deoxyribonucleases and Their Applications in Biomedicine.

Authors:  Lucia Lauková; Barbora Konečná; Ľubica Janovičová; Barbora Vlková; Peter Celec
Journal:  Biomolecules       Date:  2020-07-11

Review 3.  Biosensors based on graphene oxide and its biomedical application.

Authors:  Jieon Lee; Jungho Kim; Seongchan Kim; Dal-Hee Min
Journal:  Adv Drug Deliv Rev       Date:  2016-06-11       Impact factor: 15.470

4.  Discovery of Hepatitis C Virus NS3 Helicase Inhibitors by a Multiplexed, High-Throughput Helicase Activity Assay Based on Graphene Oxide.

Authors:  Hongje Jang; Soo-Ryoon Ryoo; Young-Kwan Kim; Soojin Yoon; Henna Kim; Sang Woo Han; Byong-Seok Choi; Dong-Eun Kim; Dal-Hee Min
Journal:  Angew Chem Weinheim Bergstr Ger       Date:  2013-01-25

Review 5.  A new helicase assay based on graphene oxide for anti-viral drug development.

Authors:  Hongje Jang; Soo-Ryoon Ryoo; Min Jae Lee; Sang Woo Han; Dal-Hee Min
Journal:  Mol Cells       Date:  2013-03-11       Impact factor: 5.034

6.  Discovery of hepatitis C virus NS3 helicase inhibitors by a multiplexed, high-throughput helicase activity assay based on graphene oxide.

Authors:  Hongje Jang; Soo-Ryoon Ryoo; Young-Kwan Kim; Soojin Yoon; Henna Kim; Sang Woo Han; Byong-Seok Choi; Dong-Eun Kim; Dal-Hee Min
Journal:  Angew Chem Int Ed Engl       Date:  2013-01-25       Impact factor: 15.336
  6 in total

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