Jin-Woo Park1, Tae-Geon Kwon, Jo-Young Suh. 1. Department of Periodontology, School of Dentistry, Kyungpook National University, Jung-Gu, Daegu, Korea. jinwoo@knu.ac.kr
Abstract
OBJECTIVE: It is unclear whether surface bioactive chemistry or hydrophilicity plays a more dominant role in the osseointegration of micro-structured titanium implants having the same surface topography at the micrometer and submicrometer scales. To understand their comparative effect on enhancing the early osseointegration of micro-rough-surfaced implants, this study compared the bone healing-promoting effect of surface strontium (Sr) chemistry that has been shown in numerous studies to super-hydrophilicity in the early osseointegration of moderately rough-surfaced clinical oral implants (SLA(®) implant) in rabbit cancellous bone. MATERIAL AND METHODS: Hydrothermal treatment was performed to incorporate Sr ions into the surface of clinical SLA implants (SLA/Sr implant). The surface characteristics were evaluated by using field emission-scanning electron microscopy, X-ray photoelectron spectroscopy and optical profilometry. Twenty screw implants (10 control and 10 experimental) were placed in the femoral condyles of 10 New Zealand White rabbits. The early osseointegration of the SLA/Sr implant was compared with a chemically modified super-hydrophilic SLA implant (SLActive(®) implant) by histomorphometric and resonance frequency analysis after 2 weeks of implantation. RESULTS: The SLA/Sr and SLActive implants exhibited an identical surface topography and average R(a) values at the micron and submicron scales. The SLA/Sr implant displayed a high amount of surface Sr content (15.6 at.%). There was no significant difference in the implant stability quotient (ISQ) values between the two groups. However, histomorphometric analysis revealed a significantly higher bone-to-implant contact percentage in the SLA/Sr implants compared with the SLActive implants in rabbit cancellous bone (P < 0.01). CONCLUSION: The results indicate that the surface Sr chemistry surpasses the effect of super-hydrophilicity in promoting the early bone apposition of moderately rough Ti surface in cancellous bone.
OBJECTIVE: It is unclear whether surface bioactive chemistry or hydrophilicity plays a more dominant role in the osseointegration of micro-structured titanium implants having the same surface topography at the micrometer and submicrometer scales. To understand their comparative effect on enhancing the early osseointegration of micro-rough-surfaced implants, this study compared the bone healing-promoting effect of surface strontium (Sr) chemistry that has been shown in numerous studies to super-hydrophilicity in the early osseointegration of moderately rough-surfaced clinical oral implants (SLA(®) implant) in rabbit cancellous bone. MATERIAL AND METHODS: Hydrothermal treatment was performed to incorporate Sr ions into the surface of clinical SLA implants (SLA/Sr implant). The surface characteristics were evaluated by using field emission-scanning electron microscopy, X-ray photoelectron spectroscopy and optical profilometry. Twenty screw implants (10 control and 10 experimental) were placed in the femoral condyles of 10 New Zealand White rabbits. The early osseointegration of the SLA/Sr implant was compared with a chemically modified super-hydrophilic SLA implant (SLActive(®) implant) by histomorphometric and resonance frequency analysis after 2 weeks of implantation. RESULTS: The SLA/Sr and SLActive implants exhibited an identical surface topography and average R(a) values at the micron and submicron scales. The SLA/Sr implant displayed a high amount of surface Sr content (15.6 at.%). There was no significant difference in the implant stability quotient (ISQ) values between the two groups. However, histomorphometric analysis revealed a significantly higher bone-to-implant contact percentage in the SLA/Sr implants compared with the SLActive implants in rabbit cancellous bone (P < 0.01). CONCLUSION: The results indicate that the surface Sr chemistry surpasses the effect of super-hydrophilicity in promoting the early bone apposition of moderately rough Ti surface in cancellous bone.
Authors: Andreas Pabst; Ashraf Asran; Steffen Lüers; Markus Laub; Christopher Holfeld; Victor Palarie; Daniel G E Thiem; Philipp Becker; Amely Hartmann; Diana Heimes; Bilal Al-Nawas; Peer W Kämmerer Journal: Biomedicines Date: 2022-04-19
Authors: Manuel M Romero-Ruiz; Francisco Javier Gil-Mur; José Vicente Ríos-Santos; Pedro Lázaro-Calvo; Blanca Ríos-Carrasco; Mariano Herrero-Climent Journal: Int J Mol Sci Date: 2019-05-09 Impact factor: 5.923
Authors: Vincent Offermanns; Ole Zoffmann Andersen; Gregor Riede; Inge Hald Andersen; Klaus Pagh Almtoft; Søren Sørensen; Michael Sillassen; Christian Sloth Jeppesen; Michael Rasse; Morten Foss; Frank Kloss Journal: Int J Nanomedicine Date: 2016-05-30
Authors: Roland Seidling; Lars J Lehmann; Manuel Lingner; Eckhard Mauermann; Udo Obertacke; Markus L R Schwarz Journal: J Orthop Surg Res Date: 2016-10-17 Impact factor: 2.359
Authors: Vincent Offermanns; Ole Z Andersen; Michael Sillassen; Klaus P Almtoft; Inge H Andersen; Frank Kloss; Morten Foss Journal: Int J Nanomedicine Date: 2018-04-11