| Literature DB >> 22407226 |
Zinka Bošnjak1, Snježana Džijan, Dinko Pavlinić, Magdalena Perić, Nataša Ružman, Ivana Roksandić Križan, Gordan Lauc, Arlen Antolović-Požgain, Jelena Burazin, Dubravka Vuković.
Abstract
The purpose of this study was to determine prevalence of Chlamydia trachomatis (Ct) urogenital infection and its serotype distribution from clinical samples in north-eastern Croatia. During a 3-year period, 2,379 urogenital samples were analyzed by real-time polymerase chain reaction (A group), while 4,846 genital swabs were analyzed by direct fluorescent antibody test (B group). 132 Ct positive specimens were genotyped by omp1 gene sequencing. The prevalence rate of Ct was 3.2 % in A and 1 % in B group. The most prevalent chlamydial genotype was E (44 %), followed by F (33 %), K (11.5 %), G (8 %), J/UW (5.3 %), D-IC (4.4 %), D-B120 (1.8 %), and B/IU, J/IU, Ia/IU (0.9 % each) serotypes. Single-nucleotide polymorphisms (SNPs) of omp1 gene were detected in E, K, and G serotypes. Some of these SNPs (C/T at position 272 and G/A at position 813 in E strain; C/T at position 884 in D strain) might represent novel omp1 variants.Entities:
Mesh：
Substances：
Year: 2012 PMID： 22407226 DOI： 10.1007/s00284-012-0106-7
Source DB: PubMed Journal: Curr Microbiol ISSN： 0343-8651 Impact factor: 2.188