Literature DB >> 22398213

Internal scatter, the unavoidable major component of the peripheral dose in photon-beam radiotherapy.

Ndimofor Chofor1, Dietrich Harder, Kay C Willborn, Björn Poppe.   

Abstract

In clinical photon beams, the dose outside the geometrical field limits is produced by photons originating from (i) head leakage, (ii) scattering at the beam collimators and the flattening filter (head scatter) and (iii) scattering from the directly irradiated region of the patient or phantom (internal scatter). While the first two components can be modified, e.g. by reinforcement of shielding components or by re-modeling the filter system, internal scatter remains an unavoidable contributor to the peripheral dose. Its relative magnitude compared to the other components, its numerical variation with beam energy, field size and off-axis distance as well as its spectral distribution are evaluated in this study. We applied a detailed Monte Carlo (MC) model of our 6/15 MV Siemens Primus linear accelerator beam head, provided with ideal head leakage shielding conditions (multi-leaf collimator without gaps) to assess the head scatter contribution. Experimental values obtained under real shielding conditions were used to evaluate the head leakage contribution. It was found that the MC-computed internal scatter doses agree with the results of our previous measurements, that internal scatter is the major contributor to the peripheral dose in the near periphery while head leakage prevails in the far periphery, and that the lateral decline of the internal scatter dose can be represented by the sum of two exponentials, with an asymptotic tenth value of 18 to 19 cm. Internal scatter peripheral doses from various elementary beams are additive, so that their sum increases approximately in proportion with field size. The ratio between normalized internal scatter doses at 6 and 15 MV is approximately 2:1. The energy fluence spectra of the internal scatter component at all points of interest outside the field have peaks near 500 keV. The fact that the energy-shifted internal scatter constitutes the major contributor to the dose in the near periphery has a general bearing for dosimetry, i.e. for energy-dependent detector responses and dose conversion factors, for the relative biological effectiveness and for second primary malignancy risk estimates in the peripheral region.
© 2012 Institute of Physics and Engineering in Medicine

Entities:  

Mesh:

Year:  2012        PMID: 22398213     DOI: 10.1088/0031-9155/57/6/1733

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  12 in total

1.  Lack of Relevant Haemogram Changes During Percutaneous Radiotherapy of Localised Prostate Cancer.

Authors:  Felix Zwicker; Benedict Swartman; Peter E Huber; Klaus Herfarth; Jürgen Debus; Henrik Hauswald
Journal:  In Vivo       Date:  2020 May-Jun       Impact factor: 2.155

2.  A simple and fast physics-based analytical method to calculate therapeutic and stray doses from external beam, megavoltage x-ray therapy.

Authors:  Lydia J Jagetic; Wayne D Newhauser
Journal:  Phys Med Biol       Date:  2015-06-04       Impact factor: 3.609

3.  The out-of-field dose in radiation therapy induces delayed tumorigenesis by senescence evasion.

Authors:  Erwan Goy; Maxime Tomezak; Caterina Facchin; Nathalie Martin; Emmanuel Bouchaert; Jerome Benoit; Clementine de Schutter; Joe Nassour; Laure Saas; Claire Drullion; Priscille M Brodin; Alexandre Vandeputte; Olivier Molendi-Coste; Laurent Pineau; Gautier Goormachtigh; Olivier Pluquet; Albin Pourtier; Fabrizio Cleri; Eric Lartigau; Nicolas Penel; Corinne Abbadie
Journal:  Elife       Date:  2022-03-18       Impact factor: 8.140

4.  Calculating and estimating second cancer risk from breast radiotherapy using Monte Carlo code with internal body scatter for each out-of-field organ.

Authors:  Takeshi Takata; Kenshiro Shiraishi; Shinobu Kumagai; Norikazu Arai; Takenori Kobayashi; Hiroshi Oba; Takahide Okamoto; Jun'ichi Kotoku
Journal:  J Appl Clin Med Phys       Date:  2020-10-30       Impact factor: 2.102

5.  In vivo measurement of dose distribution in patients' lymphocytes: helical tomotherapy versus step-and-shoot IMRT in prostate cancer.

Authors:  Felix Zwicker; Benedict Swartman; Falk Roeder; Florian Sterzing; Henrik Hauswald; Christian Thieke; Klaus-Josef Weber; Peter E Huber; Kai Schubert; Jürgen Debus; Klaus Herfarth
Journal:  J Radiat Res       Date:  2014-10-31       Impact factor: 2.724

6.  Development of clinical application program for radiotherapy induced cancer risk calculation using Monte Carlo engine in volumetric-modulated arc therapy.

Authors:  Dong-Jin Kang; Young-Joo Shin; Seonghoon Jeong; Jae-Yong Jung; Hakjae Lee; Boram Lee
Journal:  Radiat Oncol       Date:  2021-06-12       Impact factor: 3.481

7.  Monte Carlo Study of Fetal Dosimetry Parameters for 6 MV Photon Beam.

Authors:  Maryam Atarod; Parvaneh Shokrani
Journal:  J Med Signals Sens       Date:  2013-01

8.  Imaging dose in breast radiotherapy: does breast size affect the dose to the organs at risk and the risk of secondary cancer to the contralateral breast?

Authors:  Vikneswary Batumalai; Alexandra Quinn; Michael Jameson; Geoff Delaney; Lois Holloway
Journal:  J Med Radiat Sci       Date:  2015-01-07

9.  Commissioning of a PTW 34070 large-area plane-parallel ionization chamber for small field megavoltage photon dosimetry.

Authors:  Tom Kupfer; Joerg Lehmann; Duncan J Butler; Ganesan Ramanathan; Tracy E Bailey; Rick D Franich
Journal:  J Appl Clin Med Phys       Date:  2017-10-04       Impact factor: 2.102

10.  Evaluation of a new foetal shielding device for pregnant brain tumour patients.

Authors:  Seonghee Kang; Kyeong-Hyeon Kim; Sang-Won Kang; Dong-Seok Shin; Seungwan Lee; Jin-Beom Chung
Journal:  Radiat Oncol       Date:  2021-06-13       Impact factor: 3.481

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.