Literature DB >> 22395567

The controversy regarding the need for hormonal treatment in boys with unilateral cryptorchidism goes on: a review of the literature.

Barbara Ludwikowski1, Ricardo González.   

Abstract

Hormonal treatment for unilateral undescended testes continues to be recommended in some countries. We reviewed the literature in favor and against this recommendation. Since the paternity rate of men with a history of unilateral undescended testes only treated with surgery is normal, the effectiveness of hormonal treatment to produce testicular descent is low, the cost is considerable, and there are potential adverse effects, hormonal treatment for boys with unilateral undescended testes should no longer be recommended.

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Year:  2012        PMID: 22395567     DOI: 10.1007/s00431-012-1711-y

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  40 in total

1.  Importance of early postnatal germ cell maturation for fertility of cryptorchid males.

Authors:  F Hadziselimovic; B Herzog
Journal:  Horm Res       Date:  2001

2.  The single testis: paternity after presentation as unilateral cryptorchidism.

Authors:  Peter A Lee; Michael T Coughlin
Journal:  J Urol       Date:  2002-10       Impact factor: 7.450

3.  Fertility in undescended testes.

Authors:  P J Retief
Journal:  S Afr Med J       Date:  1977-10-01

Review 4.  Nordic consensus on treatment of undescended testes.

Authors:  E Martin Ritzén; A Bergh; R Bjerknes; P Christiansen; D Cortes; S E Haugen; N Jörgensen; C Kollin; S Lindahl; G Läckgren; K M Main; A Nordenskjöld; E Rajpert-De Meyts; O Söder; S Taskinen; A Thorsson; J Thorup; J Toppari; H Virtanen
Journal:  Acta Paediatr       Date:  2007-02-26       Impact factor: 2.299

5.  Cryptorchidism, orchiopexy and infertility: a critical long-term retrospective analysis.

Authors:  M Cendron; M A Keating; D S Huff; C E Koop; H M Snyder; J W Duckett
Journal:  J Urol       Date:  1989-08       Impact factor: 7.450

6.  Age at surgery for undescended testis and risk of testicular cancer.

Authors:  Andreas Pettersson; Lorenzo Richiardi; Agneta Nordenskjold; Magnus Kaijser; Olof Akre
Journal:  N Engl J Med       Date:  2007-05-03       Impact factor: 91.245

Review 7.  World Health Organization reference values for human semen characteristics.

Authors:  Trevor G Cooper; Elizabeth Noonan; Sigrid von Eckardstein; Jacques Auger; H W Gordon Baker; Hermann M Behre; Trine B Haugen; Thinus Kruger; Christina Wang; Michael T Mbizvo; Kirsten M Vogelsong
Journal:  Hum Reprod Update       Date:  2009-11-24       Impact factor: 15.610

Review 8.  Epidemiology and pathogenesis of cryptorchidism.

Authors:  H E Virtanen; J Toppari
Journal:  Hum Reprod Update       Date:  2007-11-21       Impact factor: 15.610

9.  Neoadjuvant gonadotropin-releasing hormone therapy before surgery and effect on fertility index in unilateral undescended testes: a prospective randomized trial.

Authors:  Mohamed Jallouli; Tarek Rebai; Nouha Abid; Mahdi Bendhaou; Mondher Kassis; Riadh Mhiri
Journal:  Urology       Date:  2009-04-15       Impact factor: 2.649

Review 10.  Undescended testis: current theories of etiology.

Authors:  Julia S Barthold
Journal:  Curr Opin Urol       Date:  2008-07       Impact factor: 2.309

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  8 in total

Review 1.  [Undescended testis: current treatment guidelines].

Authors:  B Haid
Journal:  Urologe A       Date:  2016-01       Impact factor: 0.639

Review 2.  A systematic review and meta-analysis of comparative studies assessing the efficacy of luteinizing hormone-releasing hormone therapy for children with cryptorchidism.

Authors:  Tao Li; Liang Gao; Peng Chen; Siyuan Bu; Dehong Cao; Lu Yang; Qiang Wei
Journal:  Int Urol Nephrol       Date:  2016-02-22       Impact factor: 2.370

3.  The timing of surgery for undescended testis - a retrospective multicenter analysis.

Authors:  Georg Hrivatakis; Wolfgang Astfalk; Andreas Schmidt; Andreas Hartwig; Thomas Kugler; Thomas Heim; Axel Clausner; Albrecht Frunder; Harduin Weber; Steffan Loff; Joerg Fuchs; Verena Ellerkamp
Journal:  Dtsch Arztebl Int       Date:  2014-09-26       Impact factor: 5.594

4.  Effects on normalized testicular atrophy index (TAIn) in cryptorchid infants treated with GnRHa pre and post-operative vs surgery alone: a prospective randomized trial and long-term follow-up on 62 cases.

Authors:  Claudio Spinelli; Silvia Strambi; Marga Busetto; Valentina Pucci; Francesco Bianco
Journal:  Pediatr Surg Int       Date:  2014-08-09       Impact factor: 1.827

5.  Operative management of cryptorchidism: guidelines and reality--a 10-year observational analysis of 3587 cases.

Authors:  Kai O Hensel; Tawa Caspers; Andreas C Jenke; Ekkehard Schuler; Stefan Wirth
Journal:  BMC Pediatr       Date:  2015-09-10       Impact factor: 2.125

6.  A cross-sectional study of cryptorchidism in children: testicular volume and hormonal function at 18 years of age.

Authors:  R Varela-Cives; R Mendez-Gallart; E Estevez-Martinez; P Rodriguez-Barca; A Bautista-Casasnovas; M Pombo-Arias; R Tojo-Sierra
Journal:  Int Braz J Urol       Date:  2015 Jan-Feb       Impact factor: 1.541

Review 7.  Congenital Hypopituitarism During the Neonatal Period: Epidemiology, Pathogenesis, Therapeutic Options, and Outcome.

Authors:  Laura Bosch I Ara; Harshini Katugampola; Mehul T Dattani
Journal:  Front Pediatr       Date:  2021-02-02       Impact factor: 3.418

8.  Neoadjuvant human Chorionic Gonadotropin (hCG) therapy may improve the position of undescended testis: a preliminary report.

Authors:  Piotr Kucharski; Jerzy Niedzielski
Journal:  Cent European J Urol       Date:  2013-08-13
  8 in total

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