Literature DB >> 22386729

Seroreactivity to LGL leukemia-specific epitopes in aplastic anemia, myelodysplastic syndrome and paroxysmal nocturnal hemoglobinuria: results of a bone marrow failure consortium study.

Susan Bell Nyland1, Daniel J Krissinger, Michael J Clemente, Rosalyn B Irby, Kendall Thomas Baab, Nancy Ruth Jarbadan, Lubomir Sokol, Eric Schaefer, Jason Liao, David Cuthbertson, Pearlie Epling-Burnette, Ronald Paquette, Alan F List, Jaroslaw P Maciejewski, Thomas P Loughran.   

Abstract

Large granular lymphocyte (LGL) leukemia is characterized by clonal expansion of antigen-activated cytotoxic T cells (CTL). Patients frequently exhibit seroreactivity against a human T-cell leukemia virus (HTLV) epitope, BA21. Aplastic anemia, paroxysmal nocturnal hemoglobinuria and myelodysplastic syndrome are bone marrow failure diseases that can also be associated with similar aberrant CTL activation (LGL-BMF). We identified a BA21 peptide that was specifically reactive with LGL leukemia sera and found significantly elevated antibody reactivity against the same peptide in LGL-BMF sera. This finding of shared seroreactivity in LGL-BMF conditions and LGL leukemia suggests that these diseases might share a common pathogenesis. Copyright Â
© 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 22386729      PMCID： PMC3312981          DOI： 10.1016/j.leukres.2012.02.001

Source DB:  PubMed          Journal:  Leuk Res        ISSN： 0145-2126            Impact factor:   3.156


  30 in total

1.  Constitutive expression of cytotoxic proteases and down-regulation of protease inhibitors in LGL leukemia.

Authors:  Ravi Kothapalli; Ratna D Bailey; Irina Kusmartseva; Shrikant Mane; P K Epling-Burnette; Thomas P Loughran
Journal:  Int J Oncol       Date:  2003-01       Impact factor: 5.650

Review 2.  The human leucocyte antigen (HLA) system.

Authors:  D Turner
Journal:  Vox Sang       Date:  2004-07       Impact factor: 2.144

3.  Absence of evidence of infection with divergent primate T-lymphotropic viruses in United States blood donors who have seroindeterminate HTLV test results.

Authors:  M P Busch; W M Switzer; E L Murphy; R Thomson; W Heneine
Journal:  Transfusion       Date:  2000-04       Impact factor: 3.157

4.  Monoclonal large granular lymphocyte proliferation in SLE with HTLV-I seroreactivity.

Authors:  P Marlton; K Taylor; S Elliott; J McCormack
Journal:  Aust N Z J Med       Date:  1992-02

Review 5.  Large granular lymphocytic leukaemia pathogenesis and management.

Authors:  Claire Dearden
Journal:  Br J Haematol       Date:  2010-12-15       Impact factor: 6.998

6.  Prevalence and clinical association of clonal T-cell expansions in Myelodysplastic Syndrome.

Authors:  P K Epling-Burnette; J S Painter; D E Rollison; E Ku; D Vendron; R Widen; D Boulware; J X Zou; F Bai; A F List
Journal:  Leukemia       Date:  2007-02-15       Impact factor: 11.528

7.  Mapping of immunogenic regions of human T cell leukemia virus type I (HTLV-I) gp46 and gp21 envelope glycoproteins with env-encoded synthetic peptides and a monoclonal antibody to gp46.

Authors:  T J Palker; M E Tanner; R M Scearce; R D Streilein; M E Clark; B F Haynes
Journal:  J Immunol       Date:  1989-02-01       Impact factor: 5.422

8.  CD3+ CD8+ CD56- clonal large granular lymphocyte leukaemia and HIV infection.

Authors:  M Pulik; F Lionnet; P Genet; C Petitdidier; L Jary; C Fourcade
Journal:  Br J Haematol       Date:  1997-08       Impact factor: 6.998

9.  Detection of human T-cell leukemia/lymphoma virus, type II, in a patient with large granular lymphocyte leukemia.

Authors:  T P Loughran; T Coyle; M P Sherman; G Starkebaum; G D Ehrlich; F W Ruscetti; B J Poiesz
Journal:  Blood       Date:  1992-09-01       Impact factor: 22.113

10.  CD20- and CD56-positive T-cell large granular lymphocyte leukemia in a human T-cell leukemia virus type 1 carrier.

Authors:  Sonoko Nakano-Akamatsu; Ryoichi Takahashi; Yukiko Sekioka; Yohei Hosokawa; Tohru Inaba
Journal:  Int J Hematol       Date:  2007-11       Impact factor: 2.490
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  6 in total

1.  Retroviral sero-reactivity in LGL leukaemia patients and family members.

Authors:  Susan B Nyland; David J Feith; Mary Poss; Thomas L Olson; Daniel J Krissinger; Bernard J Poiesz; Francis W Ruscetti; Thomas P Loughran
Journal:  Br J Haematol       Date:  2019-10-14       Impact factor: 6.998

2.  A paroxysmal nocturnal haemoglobinuria progress with waldenström macroglobulinemia along with T cell monoclonal expansion.

Authors:  Hongying Liu; Chuan He; Huanling Zhu; Xianglong Li; Chunli Yang; Dewan Zhao; Xiujin Wu
Journal:  Indian J Hematol Blood Transfus       Date:  2014-01-24       Impact factor: 0.900

3.  Frequent STAT3 mutations in CD8+ T cells from patients with pure red cell aplasia.

Authors:  Toru Kawakami; Nodoka Sekiguchi; Jun Kobayashi; Tatsuya Imi; Kazuyuki Matsuda; Taku Yamane; Sayaka Nishina; Yasushi Senoo; Hitoshi Sakai; Toshiro Ito; Tomonobu Koizumi; Makoto Hirokawa; Shinji Nakao; Hideyuki Nakazawa; Fumihiro Ishida
Journal:  Blood Adv       Date:  2018-10-23

Review 4.  Clinical Features, Pathogenesis, and Treatment of Large Granular Lymphocyte Leukemias.

Authors:  Kazuo Oshimi
Journal:  Intern Med       Date:  2017-07-15       Impact factor: 1.271

5.  Retrovirus insertion site analysis of LGL leukemia patient genomes.

Authors:  Weiling Li; Lei Yang; Robert S Harris; Lin Lin; Thomas L Olson; Cait E Hamele; David J Feith; Thomas P Loughran; Mary Poss
Journal:  BMC Med Genomics       Date:  2019-06-17       Impact factor: 3.063

6.  Lack of Viral Load Within Chronic Lymphoproliferative Disorder of Natural Killer Cells: What Is Outside the Leukemic Clone?

Authors:  Edoardo Giussani; Andrea Binatti; Giulia Calabretto; Vanessa Rebecca Gasparini; Antonella Teramo; Cristina Vicenzetto; Gregorio Barilà; Monica Facco; Alessandro Coppe; Gianpietro Semenzato; Stefania Bortoluzzi; Renato Zambello
Journal:  Front Oncol       Date:  2021-01-18       Impact factor: 6.244
  6 in total

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