OBJECTIVES: Multiple randomised trials have demonstrated lower perioperative mortality after endovascular aneurysm repair (EVAR) compared to open surgical repair for infrarenal abdominal aortic aneurysms (AAAs). However, in these trials the mortality advantage for EVAR is being lost within 2 years of repair and the patients evaluated are relatively older with no study specifically comparing EVAR and open repair for patients younger than 60 years of age. DESIGN: A retrospective analysis of prospectively collected data. MATERIALS AND METHODS: Patients younger than 60 years of age who underwent EVAR and open surgical repair for elective infrarenal AAA were identified from the 2007-09 National Surgical Quality Improvement Program (NSQIP) - a prospective database maintained at 237 centres across the United States. Univariate and multivariate analyses were performed. RESULTS: Of the 651 patients, 369 (56.7%) underwent EVAR and 282 (43.3%) underwent open repair. Thirty-day mortality for EVAR and open repair were 1.1% and 0.4%, respectively. This was not significantly different on univariate (P = 0.22) as well as multivariate (P = 0.69) analysis after controlling for other co-morbidities. On multivariate analysis, body mass index, history of stroke and bleeding disorder prior to surgery were associated with a higher 30-day mortality after AAA repair (combined open and EVAR). CONCLUSIONS: These contemporary results demonstrate that the 30-day mortality rate after open repair is similar to that after EVAR in patients younger than 60 years with infrarenal AAA. Published by Elsevier Ltd.
OBJECTIVES: Multiple randomised trials have demonstrated lower perioperative mortality after endovascular aneurysm repair (EVAR) compared to open surgical repair for infrarenal abdominal aortic aneurysms (AAAs). However, in these trials the mortality advantage for EVAR is being lost within 2 years of repair and the patients evaluated are relatively older with no study specifically comparing EVAR and open repair for patients younger than 60 years of age. DESIGN: A retrospective analysis of prospectively collected data. MATERIALS AND METHODS:Patients younger than 60 years of age who underwent EVAR and open surgical repair for elective infrarenal AAA were identified from the 2007-09 National Surgical Quality Improvement Program (NSQIP) - a prospective database maintained at 237 centres across the United States. Univariate and multivariate analyses were performed. RESULTS: Of the 651 patients, 369 (56.7%) underwent EVAR and 282 (43.3%) underwent open repair. Thirty-day mortality for EVAR and open repair were 1.1% and 0.4%, respectively. This was not significantly different on univariate (P = 0.22) as well as multivariate (P = 0.69) analysis after controlling for other co-morbidities. On multivariate analysis, body mass index, history of stroke and bleeding disorder prior to surgery were associated with a higher 30-day mortality after AAA repair (combined open and EVAR). CONCLUSIONS: These contemporary results demonstrate that the 30-day mortality rate after open repair is similar to that after EVAR in patients younger than 60 years with infrarenal AAA. Published by Elsevier Ltd.
Authors: Karl Y Bilimoria; Mark E Cohen; Angela M Ingraham; David J Bentrem; Karen Richards; Bruce L Hall; Clifford Y Ko Journal: Ann Surg Date: 2010-07 Impact factor: 12.969
Authors: Jan D Blankensteijn; Sjors E C A de Jong; Monique Prinssen; Arie C van der Ham; Jaap Buth; Steven M M van Sterkenburg; Hence J M Verhagen; Erik Buskens; Diederick E Grobbee Journal: N Engl J Med Date: 2005-06-09 Impact factor: 91.245
Authors: Monique Prinssen; Eric L G Verhoeven; Jaap Buth; Philippe W M Cuypers; Marc R H M van Sambeek; Ron Balm; Erik Buskens; Diederick E Grobbee; Jan D Blankensteijn Journal: N Engl J Med Date: 2004-10-14 Impact factor: 91.245
Authors: Brian J Manning; Sean M O'Neill; Syed N Haider; Mary P Colgan; Prakash Madhavan; Dermot J Moore Journal: J Vasc Surg Date: 2008-10-01 Impact factor: 4.268
Authors: Marc L Schermerhorn; A James O'Malley; Ami Jhaveri; Philip Cotterill; Frank Pomposelli; Bruce E Landon Journal: N Engl J Med Date: 2008-01-31 Impact factor: 91.245
Authors: Kristina A Giles; Marc L Schermerhorn; A James O'Malley; Philip Cotterill; Ami Jhaveri; Frank B Pomposelli; Bruce E Landon Journal: J Vasc Surg Date: 2009-02-26 Impact factor: 4.268
Authors: Carlo Setacci; Pasqualino Sirignano; Vittorio Fineschi; Paola Frati; Giovanna Ricci; Francesco Speziale Journal: Ann Med Surg (Lond) Date: 2017-02-20
Authors: Dustin M Thomas; Edward A Hulten; Shane T Ellis; David M F Anderson; Nathan Anderson; Fiora McRae; Jamil A Malik; Todd C Villines; Ahmad M Slim Journal: ISRN Cardiol Date: 2014-04-02