Literature DB >> 22385954

DNA-damage-induced differentiation in hematopoietic stem cells.

Pankaj K Mandal1, Derrick J Rossi.   

Abstract

Aging of hematopoietic stem cells (HSCs) is accompanied by diminished functional potential. Wang et al. now provide evidence for an HSC-specific differentiation checkpoint mediated by the transcription factor BATF, which limits self-renewal of HSCs in response to the accumulation of DNA damage. Copyright Â
© 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 22385954     DOI： 10.1016/j.cell.2012.02.011

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  16 in total

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Review 7.  Chronic inflammation and aging: DNA damage tips the balance.

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9.  Dystrophin Deficiency Causes Progressive Depletion of Cardiovascular Progenitor Cells in the Heart.

Authors:  Sarka Jelinkova; Yvonne Sleiman; Petr Fojtík; Franck Aimond; Amanda Finan; Gerald Hugon; Valerie Scheuermann; Deborah Beckerová; Olivier Cazorla; Marie Vincenti; Pascal Amedro; Sylvain Richard; Josef Jaros; Petr Dvorak; Alain Lacampagne; Gilles Carnac; Vladimir Rotrekl; Albano C Meli
Journal:  Int J Mol Sci       Date:  2021-05-10       Impact factor: 5.923

10.  Role of reactive oxygen species in the radiation response of human hematopoietic stem/progenitor cells.

Authors:  Masaru Yamaguchi; Ikuo Kashiwakura
Journal:  PLoS One       Date:  2013-07-25       Impact factor: 3.240
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