Literature DB >> 22377896

Sequencing histone-modifying enzymes identifies UTX mutations in acute lymphoblastic leukemia.

B G Mar, L Bullinger, E Basu, K Schlis, L B Silverman, K Döhner, S A Armstrong.   

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Year:  2012        PMID: 22377896      PMCID: PMC4701195          DOI: 10.1038/leu.2012.56

Source DB:  PubMed          Journal:  Leukemia        ISSN: 0887-6924            Impact factor:   11.528


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  14 in total

1.  A histone H3 lysine 27 demethylase regulates animal posterior development.

Authors:  Fei Lan; Peter E Bayliss; John L Rinn; Johnathan R Whetstine; Jordon K Wang; Shuzhen Chen; Shigeki Iwase; Roman Alpatov; Irina Issaeva; Eli Canaani; Thomas M Roberts; Howard Y Chang; Yang Shi
Journal:  Nature       Date:  2007-09-12       Impact factor: 49.962

Review 2.  Chromatin maps, histone modifications and leukemia.

Authors:  T Neff; S A Armstrong
Journal:  Leukemia       Date:  2009-03-26       Impact factor: 11.528

3.  The UTX gene escapes X inactivation in mice and humans.

Authors:  A Greenfield; L Carrel; D Pennisi; C Philippe; N Quaderi; P Siggers; K Steiner; P P Tam; A P Monaco; H F Willard; P Koopman
Journal:  Hum Mol Genet       Date:  1998-04       Impact factor: 6.150

Review 4.  Translating insights from the cancer genome into clinical practice.

Authors:  Lynda Chin; Joe W Gray
Journal:  Nature       Date:  2008-04-03       Impact factor: 49.962

5.  A method and server for predicting damaging missense mutations.

Authors:  Ivan A Adzhubei; Steffen Schmidt; Leonid Peshkin; Vasily E Ramensky; Anna Gerasimova; Peer Bork; Alexey S Kondrashov; Shamil R Sunyaev
Journal:  Nat Methods       Date:  2010-04       Impact factor: 28.547

6.  An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia.

Authors:  Klaus H Metzeler; Manuela Hummel; Clara D Bloomfield; Karsten Spiekermann; Jan Braess; Maria-Cristina Sauerland; Achim Heinecke; Michael Radmacher; Guido Marcucci; Susan P Whitman; Kati Maharry; Peter Paschka; Richard A Larson; Wolfgang E Berdel; Thomas Büchner; Bernhard Wörmann; Ulrich Mansmann; Wolfgang Hiddemann; Stefan K Bohlander; Christian Buske
Journal:  Blood       Date:  2008-08-20       Impact factor: 22.113

7.  The genetic landscape of the childhood cancer medulloblastoma.

Authors:  D Williams Parsons; Meng Li; Xiaosong Zhang; Siân Jones; Rebecca J Leary; Jimmy Cheng-Ho Lin; Simina M Boca; Hannah Carter; Josue Samayoa; Chetan Bettegowda; Gary L Gallia; George I Jallo; Zev A Binder; Yuri Nikolsky; James Hartigan; Doug R Smith; Daniela S Gerhard; Daniel W Fults; Scott VandenBerg; Mitchel S Berger; Suely Kazue Nagahashi Marie; Sueli Mieko Oba Shinjo; Carlos Clara; Peter C Phillips; Jane E Minturn; Jaclyn A Biegel; Alexander R Judkins; Adam C Resnick; Phillip B Storm; Tom Curran; Yiping He; B Ahmed Rasheed; Henry S Friedman; Stephen T Keir; Roger McLendon; Paul A Northcott; Michael D Taylor; Peter C Burger; Gregory J Riggins; Rachel Karchin; Giovanni Parmigiani; Darell D Bigner; Hai Yan; Nick Papadopoulos; Bert Vogelstein; Kenneth W Kinzler; Victor E Velculescu
Journal:  Science       Date:  2010-12-16       Impact factor: 47.728

8.  Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.

Authors:  Ryan D Morin; Nathalie A Johnson; Tesa M Severson; Andrew J Mungall; Jianghong An; Rodrigo Goya; Jessica E Paul; Merrill Boyle; Bruce W Woolcock; Florian Kuchenbauer; Damian Yap; R Keith Humphries; Obi L Griffith; Sohrab Shah; Henry Zhu; Michelle Kimbara; Pavel Shashkin; Jean F Charlot; Marianna Tcherpakov; Richard Corbett; Angela Tam; Richard Varhol; Duane Smailus; Michelle Moksa; Yongjun Zhao; Allen Delaney; Hong Qian; Inanc Birol; Jacqueline Schein; Richard Moore; Robert Holt; Doug E Horsman; Joseph M Connors; Steven Jones; Samuel Aparicio; Martin Hirst; Randy D Gascoyne; Marco A Marra
Journal:  Nat Genet       Date:  2010-01-17       Impact factor: 38.330

9.  Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.

Authors:  Gillian L Dalgliesh; Kyle Furge; Chris Greenman; Lina Chen; Graham Bignell; Adam Butler; Helen Davies; Sarah Edkins; Claire Hardy; Calli Latimer; Jon Teague; Jenny Andrews; Syd Barthorpe; Dave Beare; Gemma Buck; Peter J Campbell; Simon Forbes; Mingming Jia; David Jones; Henry Knott; Chai Yin Kok; King Wai Lau; Catherine Leroy; Meng-Lay Lin; David J McBride; Mark Maddison; Simon Maguire; Kirsten McLay; Andrew Menzies; Tatiana Mironenko; Lee Mulderrig; Laura Mudie; Sarah O'Meara; Erin Pleasance; Arjunan Rajasingham; Rebecca Shepherd; Raffaella Smith; Lucy Stebbings; Philip Stephens; Gurpreet Tang; Patrick S Tarpey; Kelly Turrell; Karl J Dykema; Sok Kean Khoo; David Petillo; Bill Wondergem; John Anema; Richard J Kahnoski; Bin Tean Teh; Michael R Stratton; P Andrew Futreal
Journal:  Nature       Date:  2010-01-06       Impact factor: 49.962

10.  Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer.

Authors:  Gijs van Haaften; Gillian L Dalgliesh; Helen Davies; Lina Chen; Graham Bignell; Chris Greenman; Sarah Edkins; Claire Hardy; Sarah O'Meara; Jon Teague; Adam Butler; Jonathan Hinton; Calli Latimer; Jenny Andrews; Syd Barthorpe; Dave Beare; Gemma Buck; Peter J Campbell; Jennifer Cole; Simon Forbes; Mingming Jia; David Jones; Chai Yin Kok; Catherine Leroy; Meng-Lay Lin; David J McBride; Mark Maddison; Simon Maquire; Kirsten McLay; Andrew Menzies; Tatiana Mironenko; Lee Mulderrig; Laura Mudie; Erin Pleasance; Rebecca Shepherd; Raffaella Smith; Lucy Stebbings; Philip Stephens; Gurpreet Tang; Patrick S Tarpey; Rachel Turner; Kelly Turrell; Jennifer Varian; Sofie West; Sara Widaa; Paul Wray; V Peter Collins; Koichi Ichimura; Simon Law; John Wong; Siu Tsan Yuen; Suet Yi Leung; Giovanni Tonon; Ronald A DePinho; Yu-Tzu Tai; Kenneth C Anderson; Richard J Kahnoski; Aaron Massie; Sok Kean Khoo; Bin Tean Teh; Michael R Stratton; P Andrew Futreal
Journal:  Nat Genet       Date:  2009-03-29       Impact factor: 38.330

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  42 in total

Review 1.  Genomics of lymphoid malignancies reveal major activation pathways in lymphocytes.

Authors:  Birgit Knoechel; Jens G Lohr
Journal:  J Autoimmun       Date:  2013-07-21       Impact factor: 7.094

Review 2.  MLL3/MLL4/COMPASS Family on Epigenetic Regulation of Enhancer Function and Cancer.

Authors:  Christie C Sze; Ali Shilatifard
Journal:  Cold Spring Harb Perspect Med       Date:  2016-11-01       Impact factor: 6.915

3.  Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization.

Authors:  Hiroyuki Kato; Kaori Asamitsu; Wendi Sun; Shojiro Kitajima; Naoko Yoshizawa-Sugata; Takashi Okamoto; Hisao Masai; Lorenz Poellinger
Journal:  Oncogene       Date:  2020-02-18       Impact factor: 9.867

4.  Epigenetic control of immunity.

Authors:  Meinrad Busslinger; Alexander Tarakhovsky
Journal:  Cold Spring Harb Perspect Biol       Date:  2014-06-02       Impact factor: 10.005

Review 5.  Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.

Authors:  Kelly Marie Arcipowski; Carlos Alberto Martinez; Panagiotis Ntziachristos
Journal:  Curr Opin Genet Dev       Date:  2016-05-03       Impact factor: 5.578

Review 6.  Chromatin modifiers and the promise of epigenetic therapy in acute leukemia.

Authors:  S M Greenblatt; S D Nimer
Journal:  Leukemia       Date:  2014-03-10       Impact factor: 11.528

7.  Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4.

Authors:  Hans-Martin Herz; Man Mohan; Alexander S Garruss; Kaiwei Liang; Yoh-Hei Takahashi; Kristen Mickey; Olaf Voets; C Peter Verrijzer; Ali Shilatifard
Journal:  Genes Dev       Date:  2012-11-19       Impact factor: 11.361

8.  UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition.

Authors:  Teresa Ezponda; Daphné Dupéré-Richer; Christine M Will; Eliza C Small; Nobish Varghese; Tej Patel; Behnam Nabet; Relja Popovic; Jon Oyer; Marinka Bulic; Yupeng Zheng; Xiaoxiao Huang; Mrinal Y Shah; Sayantan Maji; Alberto Riva; Manuela Occhionorelli; Giovanni Tonon; Neil Kelleher; Jonathan Keats; Jonathan D Licht
Journal:  Cell Rep       Date:  2017-10-17       Impact factor: 9.423

Review 9.  Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention.

Authors:  Xuejiao Tian; Saiyang Zhang; Hong-Min Liu; Yan-Bing Zhang; Christopher A Blair; Dan Mercola; Paolo Sassone-Corsi; Xiaolin Zi
Journal:  Curr Cancer Drug Targets       Date:  2013-06       Impact factor: 3.428

Review 10.  Histone-modifying enzymes: their role in the pathogenesis of acute leukemia and their therapeutic potential.

Authors:  Ly P Vu; Luisa Luciani; Stephen D Nimer
Journal:  Int J Hematol       Date:  2013-01-04       Impact factor: 2.490

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