BACKGROUND: Sweat contains glucose that can accurately reflect blood glucose. However, skin surface glucose can confound these measurements. METHODS: A perfusion method was used to rapidly harvest sweat from forearm sites on human subjects. The sweat samples were analyzed for glucose by high-performance liquid chromatography methods and compared with the results obtained with a blood glucose meter. RESULTS: The results of 23 different studies of seven individual subjects with diabetes show a strong correlation between sweat glucose and blood glucose. CONCLUSION: Sweat glucose, when properly harvested to prevent contamination from other sources on the skin's surface, can accurately reflect blood glucose levels.
BACKGROUND: Sweat contains glucose that can accurately reflect blood glucose. However, skin surface glucose can confound these measurements. METHODS: A perfusion method was used to rapidly harvest sweat from forearm sites on human subjects. The sweat samples were analyzed for glucose by high-performance liquid chromatography methods and compared with the results obtained with a blood glucose meter. RESULTS: The results of 23 different studies of seven individual subjects with diabetes show a strong correlation between sweat glucose and blood glucose. CONCLUSION:Sweat glucose, when properly harvested to prevent contamination from other sources on the skin's surface, can accurately reflect blood glucose levels.
Authors: Z Sonner; E Wilder; J Heikenfeld; G Kasting; F Beyette; D Swaile; F Sherman; J Joyce; J Hagen; N Kelley-Loughnane; R Naik Journal: Biomicrofluidics Date: 2015-05-15 Impact factor: 2.800
Authors: Jason Heikenfeld; Andrew Jajack; Benjamin Feldman; Steve W Granger; Supriya Gaitonde; Gavi Begtrup; Benjamin A Katchman Journal: Nat Biotechnol Date: 2019-02-25 Impact factor: 54.908
Authors: Jean-Philippe Lavigne; Albert Sotto; Catherine Dunyach-Remy; Benjamin A Lipsky Journal: Adv Wound Care (New Rochelle) Date: 2015-01-01 Impact factor: 4.730