Literature DB >> 22374452

Intramolecular 1,3-dipolar cycloaddition reactions in the synthesis of complex annelated quinolines, α-carbolines and coumarins.

Swarup Majumder1, Pallabi Borah, Pulak J Bhuyan.   

Abstract

In this study, we report the synthesis of several novel dihydroisoxazole-, tetrahydroisoxazole- and dihydropyrazole-fused pyrido[2,3-b]quinolines, α-carbolines, and pyrido[2,3-c]coumarins, respectively, from simple precursors and by exploring intramolecular 1,3-dipolar cycloaddition reactions involving nitrile oxides, nitrones, and nitrile imines as 1,3-dipoles.

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Year:  2012        PMID： 22374452     DOI： 10.1007/s11030-012-9358-1

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  12 in total

1.  Domino Reactions in Organic Synthesis.

Authors:  Lutz F. Tietze
Journal:  Chem Rev       Date:  1996-02-01       Impact factor: 60.622

2.  Chromeno[3,4-c]pyridin-5-ones: selective human dopamine D4 receptor antagonists as potential antipsychotic agents.

Authors:  P C Unangst; T Capiris; D T Connor; T G Heffner; R G MacKenzie; S R Miller; T A Pugsley; L D Wise
Journal:  J Med Chem       Date:  1997-08-15       Impact factor: 7.446

3.  Synthesis and antitumor activity of 4-hydroxycoumarin derivatives.

Authors:  Jae-Chul Jung; Ji-Ho Lee; Seikwan Oh; Jae-Gon Lee; Oee-Sook Park
Journal:  Bioorg Med Chem Lett       Date:  2004-11-15       Impact factor: 2.823

4.  An improved synthesis of alpha-carbolines under microwave irradiation.

Authors:  Patricia Vera-Luque; Ramón Alajarín; Julio Alvarez-Builla; Juan J Vaquero
Journal:  Org Lett       Date:  2006-02-02       Impact factor: 6.005

5.  DNA repair contributes to the drug-resistant phenotype of primary acute myeloid leukaemia cells with FLT3 internal tandem duplications and is reversed by the FLT3 inhibitor PKC412.

Authors:  C H Seedhouse; H M Hunter; B Lloyd-Lewis; A-M Massip; M Pallis; G I Carter; M Grundy; S Shang; N H Russell
Journal:  Leukemia       Date:  2006-10-26       Impact factor: 11.528

6.  Cardiopulmonary effects of antimalarial drugs. VII. Coronary vascular effects of pyridoquinolines.

Authors:  M A Ramirez; J Drimal; D M Aviado
Journal:  Toxicol Appl Pharmacol       Date:  1972-04       Impact factor: 4.219

7.  8-Methyl-4-(3-diethylaminopropylamino) pyrimido [4',5';4,5] thieno (2,3-b) quinoline (MDPTQ), a quinoline derivate that causes ROS-mediated apoptosis in leukemia cell lines.

Authors:  Sudheer Shenoy; Viraf S Vasania; M Gopal; Ashish Mehta
Journal:  Toxicol Appl Pharmacol       Date:  2007-05-04       Impact factor: 4.219

8.  Unprecedented chemical structure and biomimetic synthesis of erucalexin, a phytoalexin from the wild crucifer Erucastrum gallicum.

Authors:  M Soledade C Pedras; Mojmir Suchy; Pearson W K Ahiahonu
Journal:  Org Biomol Chem       Date:  2006-01-05       Impact factor: 3.876

9.  Phosphine-catalyzed synthesis of highly functionalized coumarins.

Authors:  Christopher E Henry; Ohyun Kwon
Journal:  Org Lett       Date:  2007-07-13       Impact factor: 6.005

10.  3-(aminoalkyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c] pyridin-5-ones as potential anticholinergic bronchodilators.

Authors:  D T Connor; P C Unangst; C F Schwender; R J Sorenson; M E Carethers; C Puchalski; R E Brown; M P Finkel
Journal:  J Med Chem       Date:  1989-03       Impact factor: 7.446
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  2 in total

1.  Iodine-catalyzed sp³ C-H bond activation by selenium dioxide: synthesis of diindolylmethanes and di(3-indolyl)selanides.

Authors:  P Seetham Naidu; Swarup Majumder; Pulak J Bhuyan
Journal:  Mol Divers       Date:  2015-05-28       Impact factor: 2.943

2.  Microwave-assisted one-pot multi-component reaction: synthesis of novel and highly functionalized 3-(pyranyl)- and 3-(dihydropyridinyl)indole derivatives.

Authors:  Pallabi Borah; P Seetham Naidu; Swarup Majumder; Pulak J Bhuyan
Journal:  Mol Divers       Date:  2014-07-11       Impact factor: 2.943
  2 in total

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