| Literature DB >> 22368725 |
Q X Wu1, X J Jin, M Draskovic, M S Crews, K Tenney, F A Valeriote, X J Yao, P Crews.
Abstract
A new tripeptide, pre-sclerotiotide F (3), was isolated from a marine sediment-derived fungus, Aspergillus insulicola, along with five known compounds, one of which was new at the time of isolation, scerotiotide F (4). The absolute configuration elucidation of the new compound was determined using a combination of NMR, HR-ESI-MS, and optical rotation analyses. Cytotoxicities were measured in vitro against selected cancer cells. The effects of pre-sclerotiotide F (3) and sclerotiotide F (4) on LPS-induced NF-κB and iNOS expression were also measured.Entities:
Year: 2012 PMID: 22368725 PMCID: PMC3285095 DOI: 10.1016/j.phytol.2011.11.005
Source DB: PubMed Journal: Phytochem Lett ISSN: 1874-3900 Impact factor: 1.679