INTRODUCTION: The objective of this study was to determine the effects of isoproterenol infusion on level of consciousness during ablation using total intravenous anesthesia. METHODS AND RESULTS: Seven patients undergoing total intravenous anesthesia for atrial fibrillation ablation were monitored for level of consciousness using bispectral EEG levels (BIS). Isoproterenol infusion was performed after the ablation during anesthesia. BIS levels prior to, during, and post-isoproterenol infusion were recorded and correlated to isoproterenol infusion doses. In all patients, BIS levels significantly increased during isoproterenol infusion (median BIS prior to infusion, 46; during infusion, 64 (p < 0.02)). With a subsequent increase in anesthetic medication, BIS levels could again be reduced. CONCLUSION: Isoproterenol infusion alters consciousness level during total intravenous anesthesia for atrial fibrillation ablation. BIS monitoring is a novel way to modulate anesthesia during ablation to potentially optimize patient comfort and ablation success.
INTRODUCTION: The objective of this study was to determine the effects of isoproterenol infusion on level of consciousness during ablation using total intravenous anesthesia. METHODS AND RESULTS: Seven patients undergoing total intravenous anesthesia for atrial fibrillation ablation were monitored for level of consciousness using bispectral EEG levels (BIS). Isoproterenol infusion was performed after the ablation during anesthesia. BIS levels prior to, during, and post-isoproterenol infusion were recorded and correlated to isoproterenol infusion doses. In all patients, BIS levels significantly increased during isoproterenol infusion (median BIS prior to infusion, 46; during infusion, 64 (p < 0.02)). With a subsequent increase in anesthetic medication, BIS levels could again be reduced. CONCLUSION:Isoproterenol infusion alters consciousness level during total intravenous anesthesia for atrial fibrillation ablation. BIS monitoring is a novel way to modulate anesthesia during ablation to potentially optimize patient comfort and ablation success.
Authors: Luigi Di Biase; Sergio Conti; Prasant Mohanty; Rong Bai; Javier Sanchez; David Walton; Annie John; Pasquale Santangeli; Claude S Elayi; Salwa Beheiry; G Joseph Gallinghouse; Sanghamitra Mohanty; Rodney Horton; Shane Bailey; J David Burkhardt; Andrea Natale Journal: Heart Rhythm Date: 2010-11-02 Impact factor: 6.343
Authors: Michael S Avidan; Lini Zhang; Beth A Burnside; Kevin J Finkel; Adam C Searleman; Jacqueline A Selvidge; Leif Saager; Michelle S Turner; Srikar Rao; Michael Bottros; Charles Hantler; Eric Jacobsohn; Alex S Evers Journal: N Engl J Med Date: 2008-03-13 Impact factor: 91.245
Authors: Thomas Crawford; Aman Chugh; Eric Good; Kentaro Yoshida; Krit Jongnarangsin; Matthew Ebinger; Frank Pelosi; Frank Bogun; Fred Morady; Hakan Oral Journal: J Cardiovasc Electrophysiol Date: 2009-08-11
Authors: Hakan Oral; Thomas Crawford; Melissa Frederick; Nitesh Gadeela; Alan Wimmer; Sujoya Dey; Jean F Sarrazin; Michael Kuhne; Nagib Chalfoun; Darryl Wells; Eric Good; Krit Jongnarangsin; Aman Chugh; Frank Bogun; Frank Pelosi; Fred Morady Journal: J Cardiovasc Electrophysiol Date: 2008-02-04