Literature DB >> 22363936

Chemical communication: conductors and insulators of screw-sense preference between helical oligo(aminoisobutyric acid) domains.

Thomas Boddaert1, Jordi Solà, Madeleine Helliwell, Jonathan Clayden.   

Abstract

(1)H NMR studies quantify the abilities of achiral amino acids to communicate a left-handed screw-sense preference from one helical Aib(4) domain to another: certain quaternary amino acids (e.g. Ac(6)c) act as effective conductors of conformational preference while others (e.g. diphenylglycine) acts as insulators. This journal is © The Royal Society of Chemistry 2012

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Year:  2012        PMID： 22363936     DOI： 10.1039/c2cc00060a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

Review 1.  Transmission of chirality through space and across length scales.

Authors:  Sarah M Morrow; Andrew J Bissette; Stephen P Fletcher
Journal:  Nat Nanotechnol       Date:  2017-05-05       Impact factor: 39.213

2.  End-to-end conformational communication through a synthetic purinergic receptor by ligand-induced helicity switching.

Authors:  Robert A Brown; Vincent Diemer; Simon J Webb; Jonathan Clayden
Journal:  Nat Chem       Date:  2013-09-15       Impact factor: 24.427

3.  A tendril perversion in a helical oligomer: trapping and characterizing a mobile screw-sense reversal.

Authors:  Michael Tomsett; Irene Maffucci; Bryden A F Le Bailly; Liam Byrne; Stefan M Bijvoets; M Giovanna Lizio; James Raftery; Craig P Butts; Simon J Webb; Alessandro Contini; Jonathan Clayden
Journal:  Chem Sci       Date:  2017-01-25       Impact factor: 9.825

4.  Flaws in foldamers: conformational uniformity and signal decay in achiral helical peptide oligomers.

Authors:  Bryden A F Le Bailly; Liam Byrne; Vincent Diemer; Mohammadali Foroozandeh; Gareth A Morris; Jonathan Clayden
Journal:  Chem Sci       Date:  2015-01-21       Impact factor: 9.825

5.  Bis-pyrene probes of foldamer conformation in solution and in phospholipid bilayers.

Authors:  Francis G A Lister; Natasha Eccles; Sarah J Pike; Robert A Brown; George F S Whitehead; James Raftery; Simon J Webb; Jonathan Clayden
Journal:  Chem Sci       Date:  2018-07-17       Impact factor: 9.825

Review 6.  1,4-Disubstituted 1,2,3-Triazoles as Amide Bond Surrogates for the Stabilisation of Linear Peptides with Biological Activity.

Authors:  Lisa-Maria Rečnik; Wolfgang Kandioller; Thomas L Mindt
Journal:  Molecules       Date:  2020-08-06       Impact factor: 4.411

7.  Scalable synthesis and coupling of quaternary α-arylated amino acids: α-aryl substituents are tolerated in α-helical peptides.

Authors:  Daniel J Leonard; Francis Zieleniewski; Isabelle Wellhöfer; Emily G Baker; John W Ward; Derek N Woolfson; Jonathan Clayden
Journal:  Chem Sci       Date:  2021-06-09       Impact factor: 9.825
  7 in total

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