Literature DB >> 22361713

Probe sialidase substrate specificity using chemoenzymatically synthesized sialosides containing C9-modified sialic acid.

Zahra Khedri1, Musleh M Muthana, Yanhong Li, Saddam M Muthana, Hai Yu, Hongzhi Cao, Xi Chen.   

Abstract

A library of α2-3- and α2-6-linked sialyl galactosides containing C9-modified sialic acids was synthesized from C6-modified mannose derivatives using an efficient one-pot three-enzyme system. These sialosides were used in a high-throughput sialidase substrate specificity assay to elucidate the importance of C9-OH in sialidase recognition.

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Year:  2012        PMID： 22361713     DOI： 10.1039/c2cc17393j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  18 in total

1.  Chemoenzymatic synthesis of sialosides containing C7-modified sialic acids and their application in sialidase substrate specificity studies.

Authors:  Zahra Khedri; Yanhong Li; Saddam Muthana; Musleh M Muthana; Ching-Wen Hsiao; Hai Yu; Xi Chen
Journal:  Carbohydr Res       Date:  2014-03-06       Impact factor: 2.104

Review 2.  Enzymatic labeling of proteins: techniques and approaches.

Authors:  Mohammad Rashidian; Jonathan K Dozier; Mark D Distefano
Journal:  Bioconjug Chem       Date:  2013-08-21       Impact factor: 4.774

3.  Chemoenzymatic synthesis of para-nitrophenol (pNP)-tagged α2-8-sialosides and high-throughput substrate specificity studies of α2-8-sialidases.

Authors:  Nova Tasnima; Hai Yu; Yanhong Li; Abhishek Santra; Xi Chen
Journal:  Org Biomol Chem       Date:  2016-12-20       Impact factor: 3.876

4.  Converting Pasteurella multocidaα2-3-sialyltransferase 1 (PmST1) to a regioselective α2-6-sialyltransferase by saturation mutagenesis and regioselective screening.

Authors:  John B McArthur; Hai Yu; Jie Zeng; Xi Chen
Journal:  Org Biomol Chem       Date:  2017-01-30       Impact factor: 3.876

5.  A facile microwave-assisted protocol for rapid synthesis of N-acetylneuraminic acid congeners.

Authors:  Jonel P Saludes; Dhananjaya Sahoo; I Abrrey Monreal
Journal:  New J Chem       Date:  2014-02-01       Impact factor: 3.591

6.  L. pneumophila CMP-5,7-di-N-acetyllegionaminic acid synthetase (LpCLS)-involved chemoenzymatic synthesis of sialosides and analogues.

Authors:  John B McArthur; Abhishek Santra; Wanqing Li; Anoopjit S Kooner; Ziqi Liu; Hai Yu; Xi Chen
Journal:  Org Biomol Chem       Date:  2020-01-08       Impact factor: 3.876

7.  One-pot SSA-catalyzed β-elimination: an efficient and inexpensive protocol for easy access to the glycal of sialic acid.

Authors:  Erickson M Paragas; I Abrrey Monreal; Chris M Vasil; Jonel P Saludes
Journal:  Carbohydr Res       Date:  2014-09-17       Impact factor: 2.104

8.  α2-6-Neosialidase: A Sialyltransferase Mutant as a Sialyl Linkage-Specific Sialidase.

Authors:  John B McArthur; Hai Yu; Nova Tasnima; Christie M Lee; Andrew J Fisher; Xi Chen
Journal:  ACS Chem Biol       Date:  2018-03-28       Impact factor: 5.100

9.  Enhanced Cross-Linking of Diazirine-Modified Sialylated Glycoproteins Enabled through Profiling of Sialidase Specificities.

Authors:  Janet E McCombs; Chunxia Zou; Randy B Parker; Christopher W Cairo; Jennifer J Kohler
Journal:  ACS Chem Biol       Date:  2015-11-16       Impact factor: 5.100

10.  Chemoenzymatic synthesis of Neu5Ac9NAc-containing α2-3- and α2-6-linked sialosides and their use for sialidase substrate specificity studies.

Authors:  Wanqing Li; An Xiao; Yanhong Li; Hai Yu; Xi Chen
Journal:  Carbohydr Res       Date:  2017-09-18       Impact factor: 2.104
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