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Literature DB >> 22359096

Family history and APOE-4 genetic risk in Alzheimer's disease.

Markus Donix¹, Gary W Small, Susan Y Bookheimer.

Abstract

Identifying risk factors for Alzheimer's disease, such as carrying the APOE-4 allele, and understanding their contributions to disease pathophysiology or clinical presentation is critical for establishing and improving diagnostic and therapeutic strategies. A first-degree family history of Alzheimer's disease represents a composite risk factor, which reflects the influence of known and unknown susceptibility genes and perhaps non-genetic risks. There is emerging evidence that investigating family history risk associated effects may contribute to advances in Alzheimer's disease research and ultimately clinical practice.

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2012 PMID： 22359096 PMCID： PMC3797601 DOI： 10.1007/s11065-012-9193-2

Source DB: PubMed Journal: Neuropsychol Rev ISSN： 1040-7308 Impact factor: 7.444

98 in total

1. Maternal age affects brain metabolism in adult children of mothers affected by Alzheimer's disease.

Authors: Lisa Mosconi; Wai Tsui; John Murray; Pauline McHugh; Yi Li; Schantel Williams; Elizabeth Pirraglia; Lidia Glodzik; Susan De Santi; Shankar Vallabhajosula; Mony J de Leon
Journal: Neurobiol Aging Date: 2011-04-22 Impact factor: 4.673

2. Increased brain activation during working memory in cognitively intact adults with the APOE epsilon4 allele.

Authors: Heather A Wishart; Andrew J Saykin; Laura A Rabin; Robert B Santulli; Laura A Flashman; Stephen J Guerin; Alexander C Mamourian; Dorothy R Belloni; C Harker Rhodes; Thomas W McAllister
Journal: Am J Psychiatry Date: 2006-09 Impact factor: 18.112

3. Functional magnetic resonance imaging and magnetoencephalography differences associated with APOEepsilon4 in young healthy adults.

Authors: Francesca M Filbey; Kelly J Slack; Trey P Sunderland; Robert M Cohen
Journal: Neuroreport Date: 2006-10-23 Impact factor: 1.837

4. Oxidative stress and amyloid-beta pathology in normal individuals with a maternal history of Alzheimer's.

Authors: Lisa Mosconi; Lidia Glodzik; Rachel Mistur; Pauline McHugh; Kenneth E Rich; Elizabeth Javier; Schantel Williams; Elizabeth Pirraglia; Susan De Santi; Pankaj D Mehta; Raymond Zinkowski; Kaj Blennow; Domenico Pratico; Mony J de Leon
Journal: Biol Psychiatry Date: 2010-11-15 Impact factor: 13.382

Review 5. Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease.

Authors: Robert W Mahley; Karl H Weisgraber; Yadong Huang
Journal: Proc Natl Acad Sci U S A Date: 2006-03-27 Impact factor: 11.205

6. Differential effects of the APOE genotype on brain function across the lifespan.

Authors: N Filippini; K P Ebmeier; B J MacIntosh; A J Trachtenberg; G B Frisoni; G K Wilcock; C F Beckmann; S M Smith; P M Matthews; C E Mackay
Journal: Neuroimage Date: 2010-08-10 Impact factor: 6.556

7. Apolipoprotein E and cognitive performance: a meta-analysis.

Authors: Brent J Small; Christopher B Rosnick; Laura Fratiglioni; Lars Bäckman
Journal: Psychol Aging Date: 2004-12

Review 8. Early-life risk factors for Alzheimer disease.

Authors: Amy R Borenstein; Cathleen I Copenhaver; James A Mortimer
Journal: Alzheimer Dis Assoc Disord Date: 2006 Jan-Mar Impact factor: 2.703

9. Heritability of magnetic resonance imaging (MRI) traits in Alzheimer disease cases and their siblings in the MIRAGE study.

Authors: Kathryn L Lunetta; Porat M Erlich; Karen T Cuenco; L Adrienne Cupples; Robert C Green; Lindsay A Farrer; Charles Decarli
Journal: Alzheimer Dis Assoc Disord Date: 2007 Apr-Jun Impact factor: 2.703

10. Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates.

Authors: Kewei Chen; Eric M Reiman; Gene E Alexander; Richard J Caselli; Richard Gerkin; Daniel Bandy; Alisa Domb; David Osborne; Nick Fox; William R Crum; Ann M Saunders; John Hardy
Journal: Am J Psychiatry Date: 2007-06 Impact factor: 18.112

17 in total

Review 1. Genetics and functional imaging: effects of APOE, BDNF, COMT, and KIBRA in aging.

Authors: Goran Papenberg; Alireza Salami; Jonas Persson; Ulman Lindenberger; Lars Bäckman
Journal: Neuropsychol Rev Date: 2015-02-10 Impact factor: 7.444

Review 2. Imaging brain effects of APOE4 in cognitively normal individuals across the lifespan.

Authors: Marine Fouquet; Florent L Besson; Julie Gonneaud; Renaud La Joie; Gaël Chételat
Journal: Neuropsychol Rev Date: 2014-08-22 Impact factor: 7.444

3. A diffusion model analysis of episodic recognition in preclinical individuals with a family history for Alzheimer's disease: The adult children study.

Authors: Andrew J Aschenbrenner; David A Balota; Brian A Gordon; Roger Ratcliff; John C Morris
Journal: Neuropsychology Date: 2016-02 Impact factor: 3.295

4. Associations between depression, sleep disturbance, and apolipoprotein E in the development of Alzheimer's disease: dementia.

Authors: Shanna L Burke; Peter Maramaldi; Tamara Cadet; Walter Kukull
Journal: Int Psychogeriatr Date: 2016-03-29 Impact factor: 3.878

5. NRG3 gene is associated with the risk and age at onset of Alzheimer disease.

Authors: Ke-Sheng Wang; Nuo Xu; Liang Wang; Lorenzo Aragon; Radu Ciubuc; Tania Bedard Arana; Chunxiang Mao; Leonora Petty; David Briones; Brenda Bin Su; Xingguang Luo; Cynthia Camarillo; Michael A Escamilla; Chun Xu
Journal: J Neural Transm (Vienna) Date: 2013-09-24 Impact factor: 3.575

6. Genetic test for the personalization of sport training.

Authors: Zakira Naureen; Marco Perrone; Stefano Paolacci; Paolo Enrico Maltese; Kristjana Dhuli; Danjela Kurti; Astrit Dautaj; Roberta Miotto; Arianna Casadei; Bernard Fioretti; Tommaso Beccari; Francesco Romeo; Matteo Bertelli
Journal: Acta Biomed Date: 2020-11-09