Literature DB >> 22354129

Yoropyrazone, a new naphthopyridazone alkaloid isolated from Streptomyces sp. IFM 11307 and evaluation of its TRAIL resistance-overcoming activity.

Mohamed S Abdelfattah1, Kazufumi Toume, Masami Ishibashi.   

Abstract

A new naphthopyridazone derivative, yoropyrazone (1), has been isolated from Streptomyces sp. IFM 11307. The structure of the new compound was established on the basis of spectroscopic analyses. Compound 1 (10 μM) in combination with TRAIL moderately showed cytotoxic activity in sensitizing TRAIL-resistant human gastric adenocarcinoma (AGS) cells.

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Year:  2012        PMID： 22354129     DOI： 10.1038/ja.2012.11

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  8 in total

1.  Heliomycin and tetracinomycin D: anthraquinone derivatives with histone deacetylase inhibitory activity from marine sponge-associated Streptomyces sp. SP9.

Authors:  Mohamed Saleh Abdelfattah; Mohammed Ismail Youssef Elmallah; Ahmed Hassan Ibrahim Faraag; Ali Mohamed Salah Hebishy; Neama Hassan Ali
Journal:  3 Biotech       Date:  2018-06-01       Impact factor: 2.406

2.  Ethanolamine Catabolism in Pseudomonas aeruginosa PAO1 Is Regulated by the Enhancer-Binding Protein EatR (PA4021) and the Alternative Sigma Factor RpoN.

Authors:  Benjamin R Lundgren; Zaara Sarwar; Atahualpa Pinto; Jack G Ganley; Christopher T Nomura
Journal:  J Bacteriol       Date:  2016-08-11       Impact factor: 3.490

3.  Sharkquinone, a new ana-quinonoid tetracene derivative from marine-derived Streptomyces sp. EGY1 with TRAIL resistance-overcoming activity.

Authors:  Mohamed S Abdelfattah; Mohammed I Y Elmallah; Adal A Mohamed; Masami Ishibashi
Journal:  J Nat Med       Date:  2017-04-04       Impact factor: 2.343

4.  Sulfotanone, a new alkyl sulfonic acid derivative from Streptomyces sp. IFM 11694 with TRAIL resistance-overcoming activity.

Authors:  Mohamed S Abdelfattah; Naoki Ishikawa; Utpal K Karmakar; Masami Ishibashi
Journal:  J Nat Med       Date:  2015-11-25       Impact factor: 2.343

5.  New phenazine analogues from Streptomyces sp. IFM 11694 with TRAIL resistance-overcoming activities.

Authors:  Mohamed S Abdelfattah; Naoki Ishikawa; Utpal K Karmakar; Kazuki Yamaku; Masami Ishibashi
Journal:  J Antibiot (Tokyo)       Date:  2015-12-16       Impact factor: 2.649

6.  Chromomycins A2 and A3 from marine actinomycetes with TRAIL resistance-overcoming and Wnt signal inhibitory activities.

Authors:  Kazufumi Toume; Kentaro Tsukahara; Hanako Ito; Midori A Arai; Masami Ishibashi
Journal:  Mar Drugs       Date:  2014-06-05       Impact factor: 5.118

7.  Valosin-containing Protein is a Target of 5'-l Fuligocandin B and Enhances TRAIL Resistance in Cancer Cells.

Authors:  Midori A Arai; Shota Taguchi; Kazuhiro Komatsuzaki; Kento Uchiyama; Ayaka Masuda; Mana Sampei; Mamoru Satoh; Sayaka Kado; Masami Ishibashi
Journal:  ChemistryOpen       Date:  2016-10-24       Impact factor: 2.911

8.  The synergistic effects of low dose fluorouracil and TRAIL on TRAIL-resistant human gastric adenocarcinoma AGS cells.

Authors:  Hong Zhu; Min Huang; Daoling Ren; Jianping He; Fen Zhao; Cheng Yi; Ying Huang
Journal:  Biomed Res Int       Date:  2013-11-13       Impact factor: 3.411
  8 in total

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