Literature DB >> 22350550

[What can blind patients see in daily life with the subretinal Alpha IMS implant? Current overview from the clinical trial in Tübingen].

K Stingl1, K U Bartz-Schmidt, D Besch, F Gekeler, U Greppmaier, G Hörtdörfer, A Koitschev, T Peters, H Sachs, B Wilhelm, E Zrenner.   

Abstract

The subretinal visual implant is a scientific research approach to restore partial vision in end-stage hereditary retinal diseases by replacing the function of the degenerated photoreceptors by microelectronic chips. In a clinical trial in Tübingen these implants were tested on voluntary blind patients. By using the implants in daily living the patients reported valuable visual information. The subretinal microchip mediates subjectively useful visual information in near as well as in distant vision.

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Year:  2012        PMID： 22350550     DOI： 10.1007/s00347-011-2479-6

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN： 0941-293X            Impact factor:   1.059


  8 in total

1.  Electrical multisite stimulation of the isolated chicken retina.

Authors:  A Stett; W Barth; S Weiss; H Haemmerle; E Zrenner
Journal:  Vision Res       Date:  2000       Impact factor: 1.886

Review 2.  Will retinal implants restore vision?

Authors:  Eberhart Zrenner
Journal:  Science       Date:  2002-02-08       Impact factor: 47.728

3.  Long-term survival of retinal cell cultures on retinal implant materials.

Authors:  E Guenther; B Tröger; B Schlosshauer; E Zrenner
Journal:  Vision Res       Date:  1999-12       Impact factor: 1.886

4.  Compound subretinal prostheses with extra-ocular parts designed for human trials: successful long-term implantation in pigs.

Authors:  Florian Gekeler; Peter Szurman; Salvatore Grisanti; Ulrike Weiler; Rolf Claus; Tim-Oliver Greiner; Michael Völker; Konrad Kohler; Eberhart Zrenner; Karl Ulrich Bartz-Schmidt
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2007-02       Impact factor: 3.117

Review 5.  [Subretinal visual implants].

Authors:  K Stingl; U Greppmaier; B Wilhelm; E Zrenner
Journal:  Klin Monbl Augenheilkd       Date:  2010-12-14       Impact factor: 0.700

6.  Extraocular surgery for implantation of an active subretinal visual prosthesis with external connections: feasibility and outcome in seven patients.

Authors:  D Besch; H Sachs; P Szurman; D Gülicher; R Wilke; S Reinert; E Zrenner; K U Bartz-Schmidt; F Gekeler
Journal:  Br J Ophthalmol       Date:  2008-07-28       Impact factor: 4.638

7.  Basic quantitative assessment of visual performance in patients with very low vision.

Authors:  Michael Bach; Michaela Wilke; Barbara Wilhelm; Eberhart Zrenner; Robert Wilke
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-10-22       Impact factor: 4.799

8.  Subretinal electronic chips allow blind patients to read letters and combine them to words.

Authors:  Eberhart Zrenner; Karl Ulrich Bartz-Schmidt; Heval Benav; Dorothea Besch; Anna Bruckmann; Veit-Peter Gabel; Florian Gekeler; Udo Greppmaier; Alex Harscher; Steffen Kibbel; Johannes Koch; Akos Kusnyerik; Tobias Peters; Katarina Stingl; Helmut Sachs; Alfred Stett; Peter Szurman; Barbara Wilhelm; Robert Wilke
Journal:  Proc Biol Sci       Date:  2010-11-03       Impact factor: 5.349
  8 in total
  6 in total

Review 1.  Pulse trains to percepts: the challenge of creating a perceptually intelligible world with sight recovery technologies.

Authors:  Ione Fine; Geoffrey M Boynton
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-09-19       Impact factor: 6.237

Review 2.  Brain Machine Interfaces for Vision Restoration: The Current State of Cortical Visual Prosthetics.

Authors:  Soroush Niketeghad; Nader Pouratian
Journal:  Neurotherapeutics       Date:  2019-01       Impact factor: 7.620

3.  Safety evaluation of "retina implant alpha IMS"--a prospective clinical trial.

Authors:  Veronique B D Kitiratschky; Katarina Stingl; Barbara Wilhelm; Tobias Peters; Dorothea Besch; Helmut Sachs; Florian Gekeler; Karl Ulrich Bartz-Schmidt; Eberhart Zrenner
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-09-16       Impact factor: 3.117

Review 4.  [Visual prostheses].

Authors:  P Walter
Journal:  Ophthalmologe       Date:  2016-02       Impact factor: 1.059

Review 5.  New Vision for Visual Prostheses.

Authors:  Alexander Farnum; Galit Pelled
Journal:  Front Neurosci       Date:  2020-02-18       Impact factor: 4.677

6.  Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS.

Authors:  Katarina Stingl; Karl Ulrich Bartz-Schmidt; Dorothea Besch; Angelika Braun; Anna Bruckmann; Florian Gekeler; Udo Greppmaier; Stephanie Hipp; Gernot Hörtdörfer; Christoph Kernstock; Assen Koitschev; Akos Kusnyerik; Helmut Sachs; Andreas Schatz; Krunoslav T Stingl; Tobias Peters; Barbara Wilhelm; Eberhart Zrenner
Journal:  Proc Biol Sci       Date:  2013-02-20       Impact factor: 5.349
  6 in total

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